1,024 search results for “single prof directeur” in the Public website
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Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes
Ceramides (CERs), cholesterol, and free fatty acids (FFAs) are the main lipid classes in human stratum corneum (SC, outermost skin layer), but no studies report on the detailed analysis of these classes in a single platform.
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Financial Market Regulation and Supervision in: The Law of the European Union
Matthias Haentjens, Jouke Tegelaar and Dorine Verheij have recently published the chapter Financial Market Regulation and Supervision in the new volume of the prestigious The Law of the European Union (previously Kapteyn and VerLoren van Themaat).
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Pharmacological resting-state fMRI in aging and dementia
How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?
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Enlightening the Primordial Dark Ages
This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.
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Public Administration: Multi-Level Governance
The public sector is increasingly a multi-level system, with interactions between public and private actors on the national, sub-national (provinces, regions) and international level and various public, semi-public and private organisations that perform public tasks. In this minor students pay attention…
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Data mining and algorithm development
Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…
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The quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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About this minor
In this minor, you will learn about the structure, working methods, and the analysis techniques used by intelligence and security agencies in the Western world.
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Kemalism in the periphery: anti-veiling campaigns and state-society relations in 1930s Turkey
This dissertations studies state-society relations in 1930s Turkey, focusing on the anti-veiling campaigns in the mid-1930s and aiming to understand the ways in which the Kemalist policies were received, interpreted, negotiated, compromised and/or resisted by various actors in the provinces.
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Necropolis journal: The Administration of an Egyptian Artisans’ Community
What was the practice of keeping the Necropolis Journal?
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Setup: Low Temperatures
A lot of our research is performed at temperatures close to absolute zero, among other reasons because this increases the sensitivity of the measurements.
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Pre-Colonial and Post-Contact Archaeology in Barbados
This volume provides one of the most comprehensive overviews of the archaeology of a single Caribbean island yet published. Drawing together scholars from the Caribbean, north America and Europe, all working from a range of disciplines within the broader scope of archaeology, and drawing upon recent…
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Neural correlates of vocal learning in songbirds and humans: cross-species fMRI studies into individual differences
Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Southeast Asian Studies (MA) (60EC)
The MA Southeast Asian Studies at Leiden University explores Southeast Asia in-depth and from the perspective of its history, literature, media, culture, religions, philosophy or philology.
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South Asian Studies (MA) (60EC)
The MA South Asian Studies at Leiden University is designed for students with an interest in studying South Asia from a range of perspectives including its history, literature, art, media, culture, religions, philosophy and philology.
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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Key publications
Key publications of the Aging and Immunity group
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The Political Narratives of Cryptocurrency Evangelists
Cryptocurrencies have exploded onto global financial markets, with the value of a single bitcoin growing from around 800 USD in 2016 to 67,000 USD in 2021.
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Co-operation with China
A delegation from Leiden University, headed by the Rector Magnificus Professor Paul van der Heijden, is currently in Xiamen, in South-East China, to conclude two agreements on intensive research and teaching collaboration with academic institutions there, and to open the first MEARC representative office…
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Triple-E lecture by Prof. Bram Büscher
Lecture
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Musika: The becoming of an artistic musical metaphysics
“Music is about everything else,” theater director Peter Sellars said upon accepting his Polar Music Prize back in 2014. Although it is about particular musical problems, Stanimiras dissertation is about ‘everything else’, too. What and how that is, could be summed up in different ways depending on…
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Computational facilities
Beowulf clusters looking for new frontiers.
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Spaces and Support for Active Learning & Teaching
Within the Vision on Teaching and Learning, one of the 8 ambitions is Activating Teaching and Learning. With the support of the Vice-Deans and Vice-Rector, Hester Bijl, the Saltswat project is working on accelerating this ambition. What is the purpose of this site? Being effective…
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TranSensusLCA
The research aims at achieving a European consensus on a harmonized LCA approach/framework to be applied in E-mobility sector. The research will focus on needs and gaps in current LCA practices in E-mobility and try to provide solutions for them based on the rich knowledge and experience represented…
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Programme structure
In the first year, the Linguistics programme will provide you with a sound basis for specialisation, while training your academic competences. In the second year, you will choose one of our four specialisations. While focusing on this track in your second and third year, you may also choose electives…
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Invited speakers
Speakers that have accepted to participate:
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UNACCOMPANIED IMPROVISATION - The Multi-textural Nature of the Guitar
Why does the textural gap between the music that one can improvise and that which one can practice and learn to play (as in completely written-out music) seem to be bigger in the case of the guitar than, for example, in that of keyboard instruments?
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Networked practices of contact
Cultural identity at the Late Prehistoric settlement of Aguas Buenas, Nicaragua, AD 500-1522
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Flora in Utopias: On Thinking Through Moving Images
How do documentary moving images and fictional narratives involve and evolve each other?
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Past Events
The Risk and Regulation Lab from organises events and workshops in Leiden and The Hague. On this page you can read reports of the events that already took place.
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Cities of the Roman Near East
The main objective of this research is to map out the cities of the Roman Near East in the imperial period, with a focus on location, city size and urban features, in order to study the form the urban system and its levels of integration.
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Development of a consistent methodology for assessment of the combined effects of metal-based chemicals to lettuce (Lactuca sativa L.)
How to improve the method in quantifying the combined effects of metal-based chemicals?
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Publications
Below you will find an overview of the publications of The Leiden Advocacy Project on Plastic.
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Terror Has Already Led to Self-Restraint
Self-censorship violates principles of a free society but few people want to take the role of the martyr.
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Packaging and accessing DNA molecules
Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.
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Ariane Briegel: 'AI literally opens new worlds for the life sciences'
Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’
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igraph - To modernize the igraph interfaces to make network analysis easier
igraph development focused on improving the most-used interfaces, which are Python, R, and Mathematica. Additionally, the developers aim to make the library and the interfaces easier to maintain, focusing on long-term sustainability. This ensures that igraph continues to be a useful tool for network…
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Mathematical modelling of adverse outcome pathways
In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.
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The Italian 'Mobile Diphthongs': A Test Case for Experimental Phonetics and Phonological Theory
This thesis investigates durational aspects of the Italian mobile diphthongs with respect to other rising diphthongs and monophthongs and it shows to what extent the monophthong/diphthong alternation still occurs in contemporary Italian.
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Versatile SNP genotyping
The SNP genotyping line offers flexible genotyping for small and large projects at affordable price and high quality. The use as SNPs as molecular markers is very versatile and can be used for a wide variety of scientific questions ranging from paternity analysis, conservatuion genetis towards QTL…
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The Százhalombatta Archaeological Expedition (SAX)
Százhalombatta-Földvar is a Bronze Age fortified tell settlement on the right bank of the river Danube, 30 km south of Budapest in Hungary. It is one of the best preserved temperate climate tells in Europe and well-known for the extraordinarily rich data it produces. Since 2014 Leiden students are welcomed…