Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Research projects

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Does roadside management in the mid-west USA increase invertebrate diversity similar to practices in Europe?

On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

“JARAK: the commoditization of an alternative biofuel crop in Indonesia” was a research program from 2010-2014 in which researchers from Indonesia and the Netherlands collaborated.

This thesis examines the impacts and challenges of water use of electric power system. This thesis found that there are large differences in water use of electricity technologies, with hydropower and thermal power being two large water users.

The Leiden University-European Center for Chinese Medicine and Natural Compounds (LUECCM) is a virtual research Centre bringing together research projects of many different researchers from different origin.

Agrian History, 5300 BC - AD 1000; C.C. Bakels

Dr. at the Department of organic chemistry, Wageningen University - the Nederlands

On the 23d of May, Sanne Rotmeijer successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sanne on this achievement!

This article offers a typology for organizational and institutional crisis management that portrays three sorts of crises: a crisis in an organization, a crisis to the organization and a crisis about the organization.

The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

When do we say violence was used in an incident? The answer may seem obvious at first. But interim results from a study by Jolien van Breen show that Dutch people are labelling events in increasingly broad contexts as violent.

Promotor: W. T. F. den Hollander, F. H. J. Redig

On this page you can find information about previous CCLS events.

PhD defence

Hortus botanicus Leiden is the first Dutch garden to receive an accreditation from Botanic Gardens International (BGCI). The Conservation Practitioner Accreditation is a certificate that recognizes the policy, knowledge & expertise and education with regard to plant conservation at an international…

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

Supervisor: Andrea Martella

Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology. They are staffed by scientists with vast experience in their field, ensuring that all researchers can count not only on the latest available technology…

Research at the BPOC/SSNMR group is comprised of the following research themes:

Tell Sabi Abyad is a major Late Neolithic settlement mound in Northern Syria, belonging to the seventh and early sixth millennium bc. This book presents the results of large-scale fieldwork conducted at the site between 1994 and 1999, under the auspices of the Netherlands National Museum of Antiquities…

Promotores: G.A. Persoon, H.H. de Iongh

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Is it possible to synthesize industrially relevant compounds in a sustainable manner through the use of light-capturing cyanobacteria?

We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

Our education programmes span the entire spectrum of Animal Sciences, Evolution, Biodiversity and Conservation, Microbial Biotechnology and Plant Sciences.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Hidden behind the Academy Building on the Rapenburg lies the oldest botanical garden of the Netherlands and one of the oldest gardens in the world. Founded in 1590 and expanded in the following centuries, the Hortus is the green heart of Leiden.

From 1550 onwards, a great interest in the natural world developed across Europe. This interest was not only stimulated by a growing knowledge of local flora and fauna, but also by the import of numerous exotic animal and plant species. Think, for instance, of researches and collectors like Gessner…

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Promotor: F.J. van Lunteren, E. Jorin

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

The Garden Club is a ProParte sub-group.

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology approaches. We aim to develop hybrid systems between light-harvesting nanoparticles and redox-enzymes (oxidoreductases)…

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Long-distance Trade in Early Medieval Landscapes (ca. 6th-12th centuries)

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.