2,030 search results for “immigratie and berger control” in the Public website
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Professional agency of beginning teachers
To what extent do beginning teachers use, create and claim agency at their school?
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Testing of a malaria vaccine gets the green light
Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Realm between Empires: The Second Dutch Atlantic, 1680-1815
Wim Klooster and Gert Oostindie present a fresh look at the Dutch Atlantic in the period following the imperial moment of the seventeenth century. This epoch (1680–1815), the authors argue, marked a distinct and significant era in which Dutch military power declined and Dutch colonies began to chart…
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Related Party Transactions and Corporate Groups: When Eastern Europe Meets the West
On 1 April 2020, Ivan Romashchenko defended his thesis 'Related Party Transactions and Corporate Groups: When Eastern Europe Meets the West'. The doctoral research was supervised by Prof. S.M. Bartman en Prof. A. Radwan (Kaunas, Lithuania).
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Taking Technological Infrastructure Seriously
On 29 June 2017, Carl Mair defended his PhD dissertation “Taking Technological Infrastructure Seriously”. The supervisors are Professor A. Schmidt and Professor G.J. Zwenne.
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PLGA-based particulate vaccine delivery systems for immunotherapy of cancer
Promotores: W. Jiskoot, F. Ossendorp
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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INFLANET - Training European Experts in Inflammation: from the molecular players to animal models and the bedside
How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?
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Dynasties - A Global History of Power, 1300–1800
For thousands of years, societies have fallen under the reign of a single leader, ruling as chief, king, or emperor. In this fascinating global history of medieval and early modern dynastic power, Jeroen Duindam charts the rise and fall of dynasties, the rituals of rulership, and the contested presence…
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Belastingbudget
On 4 March 2021, Michiel Spanjers defended his thesis 'Belastingbudget'. The doctoral research was supervised by Prof. J.P. Boer and Prof. H. Vording.
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Improving the filamentous fungus Aspergillus niger as cell factory for starch degrading enzymes
We aim to develop A. niger strains that produce more starch degrading enzymes even in the absence of starch.
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Electrical and magnetic properties of ferritin: electron transport phenomena and electron paramagnetic resonance
Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.
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Cosmic tomography with weak gravitational lensing
We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.
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Scheiding van zeggenschap en belang in de familiesfeer
On 1 October 2020, Arianne de Leeuw defended her thesis 'Scheiding van zeggenschap en belang in de familiesfeer'. The doctoral research was supervised by Prof. F. Sonneveldt and Prof. A.O. Lubbers.
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Print referencing during e-storybook reading on a SMART board for kindergartners to promote early literacy skills
This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…
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Combatting infectious diseases; nanotechnology as a platform for rational vaccine design
Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.
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Countering Terrorist Narratives: Assessing the Efficacy and Mechanisms of Change in Counter-narrative Strategies
This study presents the findings of a laboratory-based experiment testing hypothesised processes implicated in the prevention of violent radicalisation through counter-narratives. The central aims of the study were to contribute to counter-narrative theory, whilst highlighting the value of experimental…
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Rebels and Conflict Escalation: Explaining the Rise and Decline in Violence
Violence during war often involves upswings and downturns that have, to date, been insufficiently explained. Why does violence at a particular point in time increase in intensity and why do actors in war decrease the level of violence at other points? Duyvesteyn discusses the potential explanatory variables…
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Student teachers’ practical knowledge, discipline strategies, and the teacher-class relationship
Social aspects of the learning environment, also called classroom climate, are important for students’ cognitive and affective learning outcomes. In this thesis the classroom climate is operationalised by means of two components: the teacher-class relationship and classroom discipline.
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The Bosnian Tinderbox: Is Putin Holding the Wick?
In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, focus on Russia’s role in Bosnia and raise some important questions.
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Scrum in secondary chemistry education
This thesis explored the question whether Scrum methodology might function as an appropriate scaffold to enhance students’ learning and to support teachers in context-based secondary chemistry education.
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Who is Afraid of More Women in Politics, and Why? An Analysis of Public Opinion in 28 European Countries
In this paper, the authors study how individual and country-level variables interact in affecting political gender attitudes in Europe.
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Exploring Grainyhead-like 2 target genes in breast cancer
The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst
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Information battleground: Conflict perceptions motivate the belief in and sharing of misinformation about the adversary
Misinformation has emerged as a major societal concern. But why do citizens contribute to the dissemination of falsehoods online?
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Highly Efficient Activation of HCl Dissociation on Au(111) via Rotational Preexcitation
The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…
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PLATO
Platform Opleiding, Onderwijs en Organisatie Ltd (PLATO). PLATO is committed to learning, learning in schools, learning in work environments, learning in life and life.
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Research
The research of the group Learning and Behavior Problems in Education addresses learning difficulties in the areas of reading (technical reading and reading comprehension) math and writing, and examines learning-related behaviors behaviors.
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Processing Lexical Bundles
On the 4th of June, Saskia Lensink successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Saskia Lensink on this achievement!
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Solving multiplication and division problems
Latent variable modeling of students' solution strategies and performance
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Flooding and Management of Large Fluvial Lowlands
Paul Hudson, Associate Professor of Physical Geography at Leiden University College, examines human impacts on lowland rivers in his new book.
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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Are we there yet? Advances in anytime-valid methods for hypothesis testing and prediction
Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…
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Morphogenesis and heterogeneity in liquid-grown streptomyces cultures
The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.
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Intradermal delivery of nanoparticulate vaccines using coated and hollow microneedles
In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.
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Student engagement in blended learning in higher education
In what way can teachers support and enlarge student engagement in a blended learning context?
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Political exclusion and support for democratic innovations: evidence from a conjoint experiment on participatory budgeting
In this research note, Van der Does & Kantorowicz aruge that citizens that tend to experience political exclusion are often more supportive of direct and participatory forms of decision-making.
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Self-assembly of flexible and rigid structures: from colloidal molecules to lattices
Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…
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Printeger – Promoting integrity as an integral dimension of excellence in research
The mission of Printeger is to enhance research integrity by promoting a research culture in which integrity is part and parcel of what it means to do excellent research, and not just an external and restrictive control system.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Intergroup helping
What motivates people to provide help to, or seek help from other groups? And what are the psychological consequences of receiving help from another group?
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Healthcare robots and AI
Healthcare robots and AI is a project that investigates the legal and regulatory aspects of healthcare robot and Artificial Intelligence (AI) technologies