537 search results for “gene” in the Public website
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PMRA Camilla Stivers Award for Joris van der Voet Best Article in PPMG
Joris van der Voet’s article “Organizational Decline and Innovation in Public Organizations: A Contextual Framework of Cutback Management” won the 2019 Camilla Stivers Award for best article in Perspectives on Public Management and Governance.
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Joke Meijer on the Nobel Prize for the biological clock
This year's Nobel Prize for Medicine goes to the three American researchers who have unravelled the mechanism behind the biological clock. Joke Meijer, Professor of Neurophysiology and an expert in the field of the sleep-wake rhythm, explained in Dutch newspapers Trouw and NRC why this discovery is…
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Zebrafish models for disease and environmental stress
We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.
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Altering the appearance of macrophages to prevent atherosclerosis
It might be possible to prevent atherosclerosis by changing the appearance of macrophages, cells of the immune system that for example digest foreign substances. In her PhD dissertation, Baoyan Ren examined several ways to do so.
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Preventing or curing diseases with X-omics
In April, the X-omics initiative was granted 17 million euros from the Dutch Organization for Scientific Research. The subsidy is part of the National Roadmap for large-scale scientific infrastructure, intended to build or renew large-scale research facilities. What new insights will this investment…
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Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages
Publication by: Vanessa Frodermann, Janine van Duijn, Gijs van Puijvelde, Peter van Santbrink, Max Lagraauw, Margreet de Vries, Paul Quax, Ilze Bot, Amanda Foks, Saskia de Jager and Johan Kuiper. Journal of Internal Medicine. 2016;279:592-605.
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Omid Karami wins Krijn Rietveld Memorial Innovation Award
Plant scientist Omid Karami is the first winner of the Krijn Rietveld Memorial Innovation Award. The jury praises the outstanding quality of his scientific research as well as the positive societal impact and commercial potential of his work.
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Why do we like winners so much?
Hardly anyone in the Netherlands ever watches skeleton racing. But we’ll soon be glued to our TV sets when ‘our’ Kimberley Bos slides down the track at the Olympic Games. All because she stands a good chance of winning a medal. Why do we like winners so much?
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New insights into evolutionary loss of digits
Merijn de Bakker and colleagues of the IBL-research group of Prof. Mike Richardson provide a unique view on digit evolution in crocodiles and birds in their recent study published in Nature.
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Jian Wang recipient inaugural Eugene Garfield Award
The first Eugene Garfield Award for Innovation In Citation Analysis has been granted to Jian Wang, Assistant Professor in the Science Based Business Program at Leiden University.
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Sebastian Pomplun joins Oncode Institute to accelerate breakthroughs in cancer research
Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…
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Neandertal genome from Les Cottés site sequenced
On March 21 2018, a study was published in Nature, co-authored by Professor M. Soressi from the Faculty of Archaeology of Leiden University, announcing the sequencing of five new Neandertals, raising the number of high-coverage sequenced Neandertals from two to seven. A tooth lost by a Neandertal woman…
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New Master’s programme in Transfusion Medicine and Cellular and Tissue Therapies
LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.
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Leiden researchers abroad with a Rubicon subsidy
Four Leiden researchers will be gaining experience at prominent international research research institutes funded by a Rubicon subsidy from NWO. One international researcher will be coming to Leiden.
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Bioart plays with genetic building blocks
Biotechnological developments are moving fast. From genetically modified plant varieties we are now moving to cultured meat. These developments require moral interpretation - and they get it in the form of art. Lotte Pet wrote a dissertation about it.
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John van Noort appointed Professor in Biophysics
Leiden University has appointed John van Noort as Professor in Biophysics. He studies the way in which our DNA is folded and read out.
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Presentations and Lectures
Members of our research team give different types of presentations and lectures.
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Making everything we know computer-readable
Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…
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Medical Delta Professor Eline Slagboom: ‘The delta region is where everything comes together’
Professor Eline Slagboom has been studying multiple generations of families for over 20 years. She collects data on why some people age healthily and others decline early.
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PhD Theses
A full overview of BPOC/SSNMR PhD theses.
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Psychologist Bart Verkuil strikes a blow against burnout
Burnout is on the increase. It is caused by group pressure, being ‘on’ all the time and asking too much of ourselves. Clinical psychologist Bart Verkuil advises lowering our expectations.
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Here’s to the next 443 years as a bastion of freedom
‘Praesidium Libertatis is a daily responsibility.’ These were the words of Rector Magnificus Carel Stolker on 8 February during the 443rd Dies Natalis of Leiden University. The University needs to pay continuous attention to open debate if it wants to remain a bastion of freedom.
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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Aquatic eDNA: Beyond Species Presence
PhD defence
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Genome size of wild tulips determined
Leiden researcher Dr Ben Zonneveld has determined the size of the genome - the amount of DNA per nucleus - of wild tulips. His conclusion is that there are more than 87 wild species. Various possibly new species have been discovered.
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The journey of our language in prehistoric times
For decades, scholars have wondered about the development and dissemination of languages around the world. What are the odds that peoples living thousands of miles apart speak varieties of Indo-European languages that are closely related? This riddle has now partly been solved thanks to an international…
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ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
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Education that connects to market needs: new course for master’s students focuses on quality in drug development
Immediately connect with the needs of industry with your master’s degree. The new course Practical Aspects of Quality Management in Pharma and Biotech provides just that. The LACDR and LUMC set up the course together with the Biotech Training Facility, located at the Leiden Bio Science Park. The first…
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Seven new Medical Delta professors
Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.
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Microbiome ecology professor Ákos Kovács' new job feels like coming home
‘Working in Leiden is a dream come true.’ Ákos Kovács studied in his birth country Hungary and worked in Germany, Denmark and Groningen. As professor of Microbiome Ecology at IBL, he immediately started working together with his new colleagues to make discoveries about the versatile bacterial species…
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Are the brains of males different from those of females? Psychologists produce a podcast on brain research and mental health
Women are more often diagnosed with depression, whereas ADHD is much more frequently detected in men. And there are other more striking differences. What role does the brain play in mental health and what is the influence of the environment? For answers to these questions, listen to the ‘(Un)gendered…
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Non-invasive DNA-labeling tool opens doors for new research
Dutch researchers have developed a new tool to label DNA for studying chromosomes in live cells. The tool is non-invasive and can be applied in culture but also in living organisms, such as zebrafish embryos. The team published their findings in the journal Nucleic Acids Research.
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On imagination in science: ‘A good researcher is also an inventor’
As far as Daniël Pijnappels, Professor of Cellular Electrophysiology, is concerned, both researching and inventing are essential for a scientist.
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Vici grants for 7 Leiden researchers
Seven Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Scientific Research (NWO).
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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Seventeen million for Dutch X-omics Initiative
The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.
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Butterflies’ wing patterns change with the seasons
Tropical butterflies adapt to their environment to improve their chances of survival. The changes are triggered by hormone signals that transmit information about temperature to the butterflies' tissues. Biologist Ana Rita Mateus shows how a complex combination of environment, physiology and genetics…
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Cosmic recipe discovered for making glycerol
A team of laboratory astrophysicists from Leiden University managed to make glycerol under conditions comparable to those in dark interstellar clouds. They allowed carbon monoxide ice to react with hydrogen atoms at minus 250 degrees Celsius. The researchers publish their findings in the Astrophysical…
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Graphene sensors detect HIV DNA
Leiden and Jülich researchers discovered an elegant and simple approach to improve the sensitivity of graphene biosensors. These so-called ‘next generation graphene electronic biochemical sensor devices’ are able to detect very low amounts of HIV DNA thanks to their very low electronic noise.
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Tracing cancer with a simple blood test
Thanks in part to the persistence of a Leiden research group, cancer could be detected in the near future with just a single drop of blood. Not only can the diagnosis be determined at an earlier stage, but the blood test is also cheap, fast and patient friendly. The first results of this method seem…
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Major European subsidy for Leiden evolutionary biology
Paul Brakefield, Professor of Evolutionary Biology at the Institute of Biology in Leiden (IBL) has been awarded an ERC Advanced Grant for his research. He will receive 2.5 million euro to develop his research programme over a period of five years.
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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Leiden breakthrough in research on nanotherapy
Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.
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Disrupted movement makes macrophages more lethal to tuberculosis bacteria
Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…
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Government pledges millions for economic growth
The government is investing 646 million euros and has set aside a further 3.5 billion to drive economic growth in the Netherlands. Much of the National Growth Fund will be used for scientific innovations. Leiden University is involved in three of the projects.
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Promising new technique to treat cancer receives NWO grant
Biological chemist Nathaniel Martin and his team received an NWO grant to examine how blocking a specific enzyme in our body, NNMT, could be helpful in the treatment of some cancers. Trials with mice have been promising, and together with the Netherlands Cancer Institute, Martin wants to take the next…
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Better, faster and earlier diagnosis with new Metabolomics Facility
On Friday 17 April Leiden Mayor Henri Lenferink will officially open the new Metabolomics Facility of Leiden University. The facility’s ultimate goal is to prevent disease and to improve health throughout the human lifespan.
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Personal chair in ‘Stress-related psychopathology’ for Bernet Elzinga
Clinical psychologist Bernet Elzinga has been appointed as Professor of a personal chair at the Faculty of Social and Behavioural Sciences. This professorship will contribute both nationally and internationally to the broader promotion of Leiden University in the field of stress and psychopathology.
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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‘A revolution is coming in treatments for neurodegenerative diseases’
Professor by Special Appointment of Clinical Neuropharmacology Geert Jan Groeneveld will deliver his inaugural lecture entitled ‘The importance of the biomarker’ on 11 March 2022. According to him, new genetic knowledge will revolutionise drug research.