Anthe Janssen, a PhD student in the Molecular Physiology research group of Prof. Mario van der Stelt, has been awarded the Public's Choice Prize for Best Oral Presentation during the Young Medicinal Chemist Symposium '18 in Ljubljana, Slovenia.

Lecture

The Dick Stufkens Prize 2020 for the best PhD thesis of the Holland Research School of Molecular Chemistry has been awarded to Dr Mark Koenis. Koenis graduated 21 February with the distinction cum laude on his thesis 'Advanced Spectra Analysis to Determine Complex Structure and Chirality'. He describes…

Physics and Engineering Approaches to Biomedicine and Pharmacology

The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…

On this page you can find information about previous CCLS events.

Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

Koper

Research at the SBC group is comprised of the following research themes:

Promotor: H.J.M. de Groot

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.

Four of Leiden's top researchers have been awarded substantial grants by the European Research Council.

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

The CIGR comprises research groups from the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

How are the building blocks of life formed?

The lipid matrix of the skin's stratum corneum plays a key role in the barrier function, which protects the body from desiccation. The lipids that make up this matrix consist of ceramides, cholesterol, and free fatty acids, and can form two coexisting crystalline lamellar phases: the long periodicity…

Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)

How does the photoregulation mechanism work in detail?

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.

How can the combination of sound composition, astrochemistry, and epistemological analysis provide new and unexpected insights into interstellar chemical reactivity?

PhD defence

NWO Chemical Sciences has awarded a TOP-PUNT grant to a research proposal of prof. dr. Gijs van der Marel (Leiden University) and prof. dr. ir. Adriaan Minnaard (University of Groningen).

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

The Department of Biophysical Structural Chemistry studies how biological systems work at the molecular level through high-resolution structural analysis. Using state-of-the-art techniques in structural biology such as cryo-electron microscopy and X-ray crystallography we gain crucial insights into…

Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

The China Region Group develops and monitors Leiden University's cooperation with China. It is chaired by the Dean of the Faculty of Science, Prof. Jasper Knoester, and consists of representatives of Leiden University's faculties and various policy departments.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

The goal of target discovery is to identify and validate proteins and biological pathways that are involved in the disease process. Modulating these target proteins and pathways with small molecules, therapeutic proteins or other biomolecules (e.g. mRNA) could deliver an effective and safe drug or v…

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

PhD at Molecular Biology and Biochemistry Department, University of Malaga - Spain

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

Promotor: Prof.dr. E.F. van Dishoeck, Co-promotor: S. Bruderer

Lecture

Willemijn Heeren has, together with dr. Lei He (Department of Linguistics, Tübingen & Center for Forensic Phonetics and Acoustics, Zürich), received a research grant from the International Association for Forensic Phonetics and Acoustics to start a pilot project on “Between-speaker variability in dynamic…

The Dick Stufkens Prize 2021 for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Klaas van Leest for his thesis 'Open- Shell Cobalt Complexes with Redox-Active Ligands; Electronic Structure and Nitrene Transfer Reactivity'. Van Leest, who is now…

PhD defence

PhD defence

PhD defence