1,490 search results for “single photo director” in the Public website
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Mathematical modeling of cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
- Prof Dr Matthias Erb
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Journal Observatory – Toward integrated information about the openness of scholarly journals
Lots of efforts are being made to promote open science practices in scholarly publishing. However, information on the openness of scholarly journals is highly fragmented. There are various data sources that provide information on specific aspects of openness, but there is hardly any integration of these…
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Dirk Bouwmeester Lab - Quantum Optics and Quantum Information
The research program of the QO group has three leading themes: Optical Physics, Quantum Optics, and Photon-Matter Interactions. We work mostly at the boundaries between these themes with entanglement as a bridging and binding agent.
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M. Wang
Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands
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Gold nanorod photoluminescence: applications to imaging and temperature sensing
Promotor: M.A.G.J. Orrit
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Multi-angle DLS Facility
Multi-Angle Dynamic Light Scattering (MADLS) is a technique that is used to determine properties of particles in suspension. The measurements give the hydrodynamic size distribution of individual particles as well as particle clusters, and assists in the interpretation of the stability of the particles…
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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R-ELEVATION
How do plant defense genes get activated?
- Charge transfer-induced reduction of vibronic coupling for single terrylene molecules adsorbed onto hBN
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Supramolecular and Biomaterials Chemistry
Alexander Kros studies supramolecular systems in a biological environment. The unifying theme between the projects in my lab is specific molecular recognition, i.e. the intermolecular interaction between complementary molecules with high affinity and selectivity. Studying, imitating and dissecting processes…
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Robert Smit receives his PhD with distinction. ‘I am happy to be back in the lab’
An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.
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Photo exhibition 'People of Leiden'
Arts and culture, Fototentoonstelling
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Tom van der ReepScience
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Alumni
Former PhD, Bachelor and Master students of the Van Exter Lab
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Citizenship: historiography and identity formation
People in Asia increasingly feel the need for a strong identity. This is the consequence of developments such as globalisation and the realisation that Asian countries such as China and India are becoming new world powers. Professor Hilde De Weerdt studies how political ideas and national identity spread…
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Admission and application
Are you interested in the minor Intelligence Studies? Find out more about admission and application below.
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Decoding the molecular makeup of the human ovary through single-cell transcriptomics
PhD defence
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Unravelling cell fate decisions through single cell methods and mathematical models
PhD defence
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Key publications
Key publications of the Cardiovascular Pharmacology group
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Interreligious Encounter in a West African City: A Study of Multiple Religious Belonging and Identity Among the Yorùbá of Ogbómòsó, Nigeria
How has interreligious encounter in Ogbómòsó created multiple religious belongings and identities among individuals and groups?
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An artificial atom as qubit
With a pioneering project like the quantum computer, it’s a good idea not to place all your bets on a single horse. In Leiden’s Quantum Optics research group, instead of working on a Majorana-based qubit, people are working on a qubit based on an ‘artificial atom’. If that becomes the basis of the quantum…
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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About the programme
The academic executive master’s programme Cyber Security is multidisciplinary; the programme covers technological as well as legal, administrative, economic and psychological aspects of digital security.
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Dynamics of Single Protein Molecules by Temperature Cycling under Laser Heating
PhD defence
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The impact of one: single cell analysis of T cell states in human cancer
PhD defence
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Learning cell identities and (post)-transcriptional regulation using single- cell data
PhD defence
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Low-temperature spectroscopic studies of single molecules in 3-D and on 2-D hosts
PhD defence
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Long-Term Observation of Protein Dynamics via Thermal-Snapshot Single Molecule Spectroscopy
PhD defence
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Optically stimulated luminescence dating of Palaeolithic cave sites and their environmental context in the western Mediterranean
The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…
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Medical Systems Biophysics and Bioengineering
The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.
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Challenged by cognition
Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
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Interaction of oxygen and carbon monoxide with Pt(111) at intermediate pressure and temperature: revisiting the fruit fly of surface science
Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink
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Data Breaches and Effective Crisis Communication: A Comparative Analysis of Corporate Reputational Crises
Online data breaches are recurrent and damaging cyber incidents fors organizations worldwide. This study examines how organizations can effectively mitigate reputational damages in the aftermath of data breaches by hacking, through situational crisis communication strategies.
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The co-occurrence of child maltreatment and parental separation
Parental divorce or separation is for many children an adverse experience in itself. Particularly the transitional period just before and after the separation between parents, during which parents and children have to adapt to the disruptions in family life is stressful. Previous studies showed that…
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Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Systematic, phylogenetic and pollination studies of Specklinia (Orchidaceae)
Promotor: Prof.dr. E.F. Smets, Co-promotores: Dr. B. Gravendeel, F. Pupulin
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Dynasties - A Global History of Power, 1300–1800
For thousands of years, societies have fallen under the reign of a single leader, ruling as chief, king, or emperor. In this fascinating global history of medieval and early modern dynastic power, Jeroen Duindam charts the rise and fall of dynasties, the rituals of rulership, and the contested presence…
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Verbal art of the Fon (Benin)
This publication aims at the analysis of the performance of a corpus of Fongbe stories that I collected in three villages in the south of Benin in 1976 and 1977. The corpus consists of 37 stories (57.000 words). The stories aim at children’s education.
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The Van Manen Collection: Locating Literature, Lived Religion, and Lives in the Himalayas
ERC Starting Grant: The Van Manen Project. This five year project (2023-2028) is made possible with an ERC Starting Grant. It aims to (digitally) reunite all parts of the Van Manen Collection. This enables us to study it as a whole, helping us to understand the process of collection formation. More…
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Accurate Probabilities for Highly Activated Reaction of Polyatomic Molecules on Surfaces Using a High-Dimensional Neural Network Potential: CHD3
An accurate description of reactive scattering of molecules on metal surfaces often requires the modeling of energy transfer between the molecule and the surface phonons. Although ab initio molecular dynamics (AIMD) can describe this energy transfer, AIMD is at present untractable for reactions with…
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Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Dr. Theo Reijmers
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Cathodic corrosion
Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.