In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

Lecture, Workshop

One of the highlights during the fieldwork in Schoningen lead by Prof. dr. Thijs van Kolfschoten in 2013 was the opening of the museum and research center paläon on June 24. To the realisation of the museum, the Faculty of Archaeology made ​​a significant contribution. Many of the results of the research…

A team of researchers at the Institute of Biology Leiden, in collaboration with scientists from Utrecht University, has discovered a novel approach to improve the production of antibiotics and enzymes in the soil bacteria Streptomycetes.

Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…

The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Research from the Living Lab is important for society. For example, scientists from the Living Lab discovered that the pesticide thiacloprid is up to 2,500 times more harmful to insects than was thought on the basis of regular lab research. Partly because of this discovery, the European Commission decided…

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

On Friday, 29 October 2021 (15.15-17.00), this year’s lecture will be delivered by Prof. Howard Louthan, (University of Minnesota, Minneapolis, USA) at the Faculty Club of Leiden University. It will be titled ‘Revisiting a Renaissance Classic: Theuerdank, Maximilian I (1486-1519) and the Discovery of…

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…

The Drug Discovery and Safety specialisation consists of compulsory and optional components.

In this project the already developed parcel based historical GIS (HISGIS) for the Dutch province of Friesland (Frisia) will be extended with a series of crucial datasets and map layers.

This book connects labour history, global history and the institutional or political history of international organisations.

Antoni van Leeuwenhoek, the father of microbiology, died 300 years ago. 2023 has therefore been designated the Antoni van Leeuwenhoek year. The new Unimaginable exhibition in Rijksmuseum Boerhaave is about the amazing world that Van Leeuwenhoek made visible. What was so special about the way he worked?…

In this year in review we show you various projects we're very proud of. Driven by our values at the Faculty of Social and Behavioural Sciences.

Supervisor: Maarten Doornbos

The International Labour Organisation (ILO) was established in 1919 based on the premise that social justice is a condition for lasting peace. On February 2019 the ILO celebrated its 100th anniversary with an international symposium to consider the future of the ILO.

How have British cities changed in the years since the Second World War? And what drove this transformation? This innovative new history traces the development of the post-war British city, from the 1940s era of reconstruction, through the rise and fall of modernist urban renewal, up to the present-day…

The Leiden Academic Centre for Drug Research (LACDR) is responsible for the research and education in Bio-Pharmaceutical Sciences carried out at Leiden University.

A Leiden and Mainz (Germany) based team studies the activities of early humans in a 125,000 years old Last Interglacial ecosystem, formerly exposed in a large open cast brown coal pit near Halle (Germany). The Last Interglacial is an important warm-temperate period, showing the full flora and fauna…

Life Sciences Artificial Intelligence Data Science

Festival

Leiden University is 444 years old this year! And we have big plans to celebrate this special birthday in 2019 - together with the people of Leiden and The Hague.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

Supervisor: Anna Vlachodimou

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.

PhD defence

At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.

This book covers the story of Greece and its central role in our understanding of European civilization, from the Palaeolithic era (400,000 BP) to the early modern period (1950 AD).

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Promotor: Prof.dr. M.K. Richardson

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Find out how to apply for Drug Discovery and Safety at Leiden University by following our step-by-step guide.

Key publications of the Computational Drug Discovery group

Do you have questions about the Bio-Pharmaceutical Sciences master’s programme or the specialisation Drug Discovery and Safety? Please contact us.

The Faculty of Science celebrated the Chinese New Year on 26 January, with an event that was organised together with the Leiden Science China community. After a warm welcome and New Year Wishes by Dean Geert de Snoo, visitors could participate in various activities, such as a calligraphy lesson.

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

As a critical commemoration of its centenary, this book presents a mosaic of one hundred carefully curated fragments by expert authors, shedding light on politics, economy, society, culture, gender, and arts in a hundred years of Turkey.

On this page you can find information about previous CCLS events.