In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Delineating psychophysiological endophenotypes of social anxiety disorder

Does a moving hybrid zone leave a genomic footprint?

The portal for prospective Indonesian Students contains information about the possibilities to study at Leiden University in the Netherlands.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

Overkleeft

Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…

In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

Research into the evolutionary backgrounds of our diets can help us make the right choices in diet, health and lifestyle.

The single cell group (SCG) is part of the Metabolomics & Analytics Centre Our research is centered around developing innovating analytical methods tailored for small-volume, or single cell analysis to enable metabolomics-driven systems biology in personalized health strategies. We are always on…

In order to optimize treatment, it is necessary to closely monitor and manage the patient’s health status by means of ‘precision diagnostics, personalized prognosis and targeted therapy’. The specialisation combines the techniques and applications of these sensing (monitoring) and stimulation techniques.…

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

Doctoral Thesis

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

The master’s specialisation BioTherapeutics at Leiden University is a two-year programme which trains students in research in specific drug delivery techniques. The programme also examines the development of new therapeutic approaches to treat immune-based disorders, such as atherosclerosis, metabolic…

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

Daniela Kraft's group has succeeded in creating a network of microparticles that is both strong and completely flexible. This may sound simple, yet they are the first in the world to succeed in doing so. A real breakthrough in soft matter physics.

Scientists have developed a material that breaks one of the fundamental principles governing many physical systems. Ordinary materials transmit external forces equally, no matter where the pressure comes from. The newly developed material breaks this rule and could potentially be of interest in soft-robotics…

The research question is that unconscious perseverative cognition (UPC) is responsible for a considerable part of cardiovascular (CV) activity that occurs even in the absence of threats and other stressors that one may encounter in one’s daily life.

This research project studies the distribution and impact of medieval malaria in the Netherlands.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

YAL now has its own lecture series! In collaboration with Studium Generale, we organise ‘Young Academy Leiden lectures'.

In a lot of research on education, general didactic principles are applied to a particular area of study. ‘But every field of study also has its own ways of thinking’, argues professor Fred Janssen. ‘If you can identify those ways of thinking, then you have a lot of indicators for how you can best organise…

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

Lecture

Can thrips resistance in strawberry be explained based on secondary metabolite profiles and plant morphological traits?

With a perspective-based approach to education, students' knowledge, skills and attitude are linked.

Investigating neurobiological endophenotypes of Social Anxiety Disorder

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

Day-to-day activities are important in the development of social identities, the establishment of social standing, and the communal understanding of societal rules. This perspective is broadly referred to as practice theory and relates to the power of an overarching social structure and the individual…

Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’

Supervisor: Gerard van Westen

Supervisor: Lizi Xia

The research group Science Communication and Society has been physically within the Institute of Biology (IBL) since 2012 and has become a formal part of the institute in 2018. The mission of this group is understanding how science communication works to improve the interaction between science and s…

The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.

Supervisor: Anna Vlachodimou

Do natural soundscapes affect migratory decisions of fishes moving up and down rivers and is this process disturbed by vessel sounds?

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.

Exploring the landscapes of mental health and cardiometabolic research.

Are traces of fire use detectable in ancient hominin genomes?

proefdieren dierproeven universiteit leiden geneesmiddelonderzoek geneesmiddelen

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Five talks will be given during the Leiden Science Family Day: two children's lectures and three lectures for adults. Will you be there ?

Correctly interpreting the patterns of fire evidence in the archaeological record will illuminate the origin of human fire use.