On 20 September 2023 Mark van de Water successfully defended a doctoral thesis and graduated.

Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Are predictive archaeological maps a reliable tool to play an important role in the spatial planning? One of the goals of this project was to develop best practices for the production and application of the models.

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Can zebrafish larvae be used as a behavioural model for screening natural products as potential neurotropic drugs?

Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…

Promotor: J.P. Abrahams, Co-Promotor: N.S. Pannu

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

This thesis studies the relationship of the town al-Fusṭāṭ, located at the southern end of the Nile delta in Egypt, and its hinterland in the period between the town’s foundation in A.D. 641 and the arrival of the Abbasids in 750.

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Description of Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT) (2004 - 2007)

The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.

PhD defence

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

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How can we further streamline the development of software for the government? Leiden University and ICTU are to investigate this in a joint research project that was launched on 6 July 2016.

Every January, students of the Minor Sustainable Development have the opportunity to put what they’ve learned over the last few months into practice in a choice of exciting and practical courses called Area Studies. This year, for the first time, there was a choice of four locations: The Netherlands,…

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Presenting case studies by both senior and emerging scholars, it makes mandatory reading for anyone interested in the challenges of governance, citizenship and development faced by the people of India’s North East.

Monday 5 September the eighth edition of the interdisciplinary Minor Sustainable Development started. With 65 students coming from more than 20 different disciplines we've a record number of students and backgrounds.

What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?

The Edinburgh Medal 2016 had been awarded to both Kevin Govender of the Office of Astronomy for Development (OAD) and the International Astronomical Union (IAU). The award is a recognition for furthering education and technological capacity worldwide through the inspirational science of astronomy. The…

The authors systematically search and review relevant definitions of Security by Design (SbD) in comparison with Privacy by Design (PbD).

Our childhood years largely determine how we will fare later in life. In the first two decades of our life, our brain is still developing, which is clearly reflected in our behaviour. By studying how the young brain develops and how children behave, researchers can learn important information about…

Visualization of biomolecules in living cells by tagging with gold nanoparticles.

The Sustainable Development minor now has its own Facebook page. Do you want to stay up to date on all activities pertaining to the minor? If so, sign up as a fan by clicking the

All the world leaders have had to choose an approach during the global Covid-19 crisis. But which approach is the most effective? André Gerrits, Professor of International Studies & Global Politics, who lectures in the BA International Studies, is observing some interesting developments. ‘Democracies…

Cardiovascular diseases are the leading cause of death across the world. Professor Johan Kuiper of Leiden University carries out research to develop a vaccine for arteriosclerosis, which is the main cause of cardiovascular diseases. With the aid of a European research grant of six million euros he is…

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Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.

Unraveling the immune-suppressive actions of drugs like prednisone.

Archaeologist Maikel Kuijpers participated in the development of the boardgame Epoch: Early Inventors. “This game is inspired by the major innovation that happened in prehistoric times. A topic that has my interest and that I teach here in Leiden.

How does the endocannabinoid system in the zebrafish function at the molecular and phenotypic levels and how is it linked to the stress axis?

The overall aim of the project is to investigate interests and their development over time in a daily life context, with particular attention for the transition from late secondary to post secondary education, and from late post secondary education to early career.

It sounds futuristic, but it is possible: the creation of miniature organs of patients in order to study them and see how diseases develop and can be treated. This is what researchers from the LUMC, Twente University (UT), UMCG, TU Delft and the Hubrecht Institute hope to achieve in the next ten years…

A new regional atlas, with information about the presence of pesticides in surface waters, has been developed by the Institute of Environmental Sciences (CML) in collaboration with Royal Haskoning DHV. The aim of the regional pesticide atlas is to support decision making at local and regional levels,…

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

As humans we have a tendency to judge certain actions as either right or wrong. Where does our moral sense come from? We found evidence that infants who are only one year old prefer those who comfort as opposed to ignore another who is sad.

Does the university value teaching less than research? Can you advance in science without academic awards? Which scholars inspire you? Does the university pay enough attention to both your academic achievements and your personal well-being?

This paper provides an initial answer to the question regarding eco-labels: ‘How can we make the development of eco-labels more structured and transparent?’

The literature indicates that teacher professional development and learning may be improved by using formative assessment procedures. This thesis focuses on a specific form of formative assessment, negotiated assessment, which is characterised by the exchange of views between assessor and assessee and…

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.