Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

Leiden University has participated in an international study carried out by the CARMENES consortium, which has discovered two small, terrestrial planets around Teegarden’s Star. The planets have masses similar to Earth and their temperatures could be mild enough to sustain liquid water on their surf…

In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

Behavioural biologist Wouter Halfwerk has been awarded a 2-year outgoing Rubicon-grant from NWO. He will be working at the Smithsonian Tropical Research Institute with bats and frogs to understand the evolution of multimodal communication.

The Institute of Psychology is committed to play a prominent role in teaching and research at the national and international level.

An essential protein that regulates our heart beat turns out to be important for cancer cells as well. The discovery might open novel treatment strategies for fighting metastasis. Publication in Science Signaling on April 4th.

Drs. Julia Hillger won the first prize for the category

A signal that is present both in the centre of our Milky Way and in distant places in the universe could reveal the origin of dark matter. This is what Leiden physicist Alexey Boyarsky concludes in an article in Physical Review Letters.

Electrical signals travel like a wave through our neural pathways. The mathematical models for these movements could not yet properly describe all the biological properties of the nerves. PhD student Willem Schouten-Straatman changed this by improving the existing models. ‘I hope that one day we will…

How do macrophages and neutrophils contribute to metastatic onset?

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

Data science is now growing fast in many places, but scholars at Leiden University have been developing data science techniques for a long time already. Thanks to their broad-based expertise, Leiden statisticians are currently combining the achievements in statistics with the latest methods of statistical…

Kros

The mission of the Plant Sciences cluster is to contribute to the sustainable production of high-quality crops, flowers and high-value bio-based products, and to contribute to the maintenance and restoration of biodiversity in natural ecosystems. This is realised by generating fundamental knowledge…

What is the Electronics Department?

The STRINGS project is mapping development pathways for science, technology and innovation that best address the UN Sustainable Development Goals. A consortium of seven universities led by Tommaso Ciarli at SPRU at the University of Sussex and the UNDP (United Nations Development Programme) have worked…

We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

Getting personal

How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?

What is the role of auxin in the initiation and process of somatic embryogenesis?

Machine learning - on classical computers- has made great progress in the past five years. Computer translation of speech and text is just one example. In Leiden, some researchers expect that machine learning, empowered by quantum systems, even if they only contain a few dozen qubits, can lead to a…

Sophia aims to create equal opportunities and promote a better working climate for female academic staff at Leiden University.

Assessing the effects of landscape and land-use changes on the visibility of archaeological landscapes in Central-Southern Italy.

A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.

The Collective Experience of Empathic Data Systems (CEEDs) consortium developed novel integrated technologies that support experiencing, analysing and understanding of very large datasets.

MRFM combines the principles of magnetic resonance and atomic force microscopy.

The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…

LION offers a PhD program in which candidates carry out independent research on a specific topic, culminating in a PhD thesis.

Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…

Digital media are everywhere and are therefore a major part of our lives and the lives of our children. The new specialisation in Digital Media in Human Development focuses on the opportunities and challenges of digital media in child rearing and education.

The Faculty of Humanities has two advisory groups for Diversty & Inclusion: one for staff members and one for students.

Using brain imaging to discover the area in the brain that recognizes emotion.

Are you a professional and do you want to reap the benefits of the educational experimental garden? Explore the possibilities for ‘mixed classrooms’ here. You also have the opportunity to organise your own education together with the Honours Academy.

The celebration of our up-and-coming science talent, that is the Psychology Science Day. Students stand proudly by their research posters and enrich the insights of fellow students, PhD candidates, postdocs and faculty with their explanations.

To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…

Who shall be responsible or liable when damage is caused by Global Navigation Satellite System (GNSS)? Is it fair enough to force a GNSS provider to bear the burden of compensation given GNSS open signals are provided free of charge? And are current international laws adequate to deal with those questions?…

For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food.

Synchronised heart rates and skin conductance tell us that people are attracted to each other. This explains why we feel a romantic ‘click’ with some people and not with others. This is the result of research by psychologist Eliska Prochazkova from the Leiden Institute for Brain and Recognition, which…