The research at The Metabolomics & Analytics Centre is centered around developing innovating analytical methods to enable metabolomics-driven systems biology in personalized health strategies.

Almost all languages of Europe and of a large part of western Asia belong to a single language family, which is called Indo-European, and which includes modern languages like English, Dutch, Russian, Farsi, but also ancient ones like Ancient Greek, Latin, Hittite and Sanskrit.

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

Relevant publications of the CIGR participants.

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

An important award like the Spinoza Prize, the 'Dutch Nobel Prize', generates lots of media attention. An overview.

Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…

A high performance computer or supercomputer owes its massive processing capacity to the fact that it chops a single overarching task into a whole series of smaller tasks. It simultaneously tackles each of those smaller problems.

Since the start of academic year 2020-2021 LUGO started working on new goals to increase the effect of our work within Leiden University. Below, the goals for the current academic year will be explained. For now, LUGO will continue to work on the accomplishment of the goal called 'Reduction of single…

Leiden Law School offers four different Bachelor’s (LLB) programmes.

High throughput microscopy

GitLab is a single application for the entire software development lifecycle. We use the Leiden University gitlab services

Leiden University supports refugee students by improving access to education, removing obstacles to academic success and encouraging contact with fellow students and staff. In doing so, we strive to contribute to an inclusive climate at Leiden University.

The guest rooms are located on the top floor of our institute.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?

Valérie Pattyn, Assistant Professor at Leiden University, researched

ASLU 13

All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.

This volume offers an innovative analysis of Roman political culture in Italy from the first to the sixth century AD on the basis of seven case studies.

The Mathematical Institute is one of the eight institutes of the Faculty of Science. The institute operates as a single unit defined by the activities of its members.

PhD defence

The quantum nature of matter and light has grown into a broad and fruitful research field for theorists and experimentalists alike. It combines foundational research with toward applications, the most well known of which is the quantum computer.

Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

Can we determine the 3D structure of a chemotaxis core complex using single-particle reconstructions via cryo-EM?

The van Exter group has an extensive history of prior research in classical and quantum optics. As former part of the group of Han Woerdman, we have studied topics as diverse as:

This minor is developed for third year students and is only accessible for bachelor students who have obtained their ‘propedeuse’, we are sorry to tell you HBO students cannot apply.

How did interests outside the scope of the Dutch chartered trading companies influence the career-paths of Dutch colonial governors?

PhD defence

How to come to valid risk stratification of alcohol use disorder?

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)

In June-August 2010 large scale excavations were executed on the cemetery belonging to the monastery, an area now termed the Paardenmarkt, by Hollandia Archeologen in cooperation with Leiden University. During the course of nine weeks, the students from the former minor Human Osteoarchaeology excavated…

Research question

North, Middle and South America together constitute the single largest area in World Archaeology that is taught as a single focus. It is also the only major world area that saw societies develop from hunter-gatherers to early empires entirely independent from developments in Eurasia & Africa. It is,…

In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…

It is advisable to open Dutch bank account once you move to The Hague (if you do not have one already), as it will allow you to get many other services such as a mobile phone contract, transportation, etc.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Exhibition

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

Scientific research is the main focus of our program. We expect new students to understand what it is and how it works.

The research program of the QO group has three leading themes: Optical Physics, Quantum Optics, and Photon-Matter Interactions. We work mostly at the boundaries between these themes with entanglement as a bridging and binding agent.

Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Lots of efforts are being made to promote open science practices in scholarly publishing. However, information on the openness of scholarly journals is highly fragmented. There are various data sources that provide information on specific aspects of openness, but there is hardly any integration of these…