1,442 search results for “lipid china last” in the Public website
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Impact and innovation
In developing cooperation on research and education with China, Leiden University focuses on projects that promote innovation, have an impact on science, and benefit society
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Cooperation
Leiden University has long had a special interest in and relationship with China.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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Structure and regulation in photosynthesis
Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…
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Freud and China
Lecture
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Frank Dikötter to receive honorary doctorate at Dies Natalis 2017
Historian Frank Dikötter will receive an honorary doctorate from Leiden University for his work on the history of the Chinese Republican period and the People's Republic of China under Mao. He will be awarded the honorary degree during the university's Dies Natalis celebrations on 8 February 2017.
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Student lectures for senior citizens: ‘You can learn a lot from other generations’
Connecting generations, reducing loneliness and slowing mental decline: these are goals of the Oud Geleerd Jong Gedaan foundation’s lectures, which are given by students. What is it like to be a student giving these lectures? And what do the seniors think of them?
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Chinese and Dutch Teachers of English have different opinions about cultures associated with the English language
Teachers of English as a foreign language in China and the Netherlands have different notions of themselves as teachers in relation to cultures associated with the English language. This is stated in the doctoral thesis of Dadi Chen, who graduates from the Leiden University Graduate School of Teaching…
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Innovating China: Governance and Mobility in China’s New Economy
PhD defence
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Fetal laser surgery as a last resort
For his dissertation, Joost Akkermans searched for areas of improvement for delicate fetal laser surgery with Twin Transfusion Syndrome (TTS). This syndrome occurs in the Netherlands 60 to 70 times a year among single-egg twins sharing one placenta. Treatment is possible, but not without risk. Inaugural…
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Last ILS Lunch Seminar of 2018 on Global Tax Governance
Last Thursday, the final ILS Lunch Seminar of 2018 took place. Irma Mosquera Valderrama, Adrián Grant and Frederik Heitmüller gave two very insightful presentations on Global Tax Governance, part of the EU-ERC project ‘A New Model of Global Governance in International Tax Law Making’ (GLOBTAXGOV).
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The last ILS Lunch Seminar of 2019 in hindsight
On Thursday 12 December, the last ILS Lunch Seminar of 2019 took place. Cecily Rose and Eduard Fosch Villaronga gave two very insightful presentation on their current and future research.
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Cardiovascular and Metabolic Therapeutics
This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…
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LED3 Drug Discovery Case Studies
To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.
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Systematic investigations into the role of ceramide subclass composition on lipid organization and skin barrier
PhD defence
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Lipid signaling and inflammation: metabolomics for better diagnosis and treatment strategy
PhD defence
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
PhD defence
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Regulation of the immune response by unsaturated lipid mediators in the context of the osteoarthritic joint
PhD defence
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Biomarker discovery in diabetes mellitus and lipid metabolism: Multi-platform glyco(proteo)mic approaches
PhD defence
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Natural Products Lab
We focus on natural products research, traditional medicine, ethnobotany and phytochemistry.
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LACDR PhD Portal
The objective of the PhD Education and Supervision program is to educate PhD candidates in becoming professionals who are competent to conduct scientific research in the field of the pharmaceutical sciences independently.
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Intradermal delivery of nanoparticulate vaccines using coated and hollow microneedles
In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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Biological, Soft and Complex Systems
We study the physics of a broad range of biological and soft materials
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Formulation of influenza T cell peptides: In search of a universal influenza vaccine
Promotoren: G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Systems pharmacology of the endocannabinoid system
What are the functions of the endocannabinoid system?
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Cholesterol metabolism and hematopoiesis interaction in atherothrombosis
Cardiovascular disease is the leading cause of death worldwide.
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax
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New polymyxin antibiotics for old problems: addressing nephrotoxicity and resistance
Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…
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Barrier properties of an N/TERT based human skin equivalent
Human skin equivalents (HSEs) can be a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings.
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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Research
Leiden University seeks to bring knowledge, academic top talents, and resources from Leiden and China together in mutually beneficial joint research projects that are content-driven, based on existing excellent research.
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Study in Leiden
Leiden University offers many possibilities to Chinese students that want to study abroad.
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About the programme
The two-year MA in Chinese Studies, a specialisation of Leiden University’s master's in Asian Studies, combines content courses with intensive and advanced language training, outstanding teaching, and world-class resources to bring you the only qualification of its calibre offered in the Netherlands…
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Daniela Stockmann awarded Goldsmith Book Prize
Leiden University political scientist Daniela Stockmann has been awarded the 2015 Goldsmith Book Prize for best academic book in the field of media, politics, and public policy. Stockmann's 'Media Commercialization and Authoritarian Rule in China' (Cambridge University Press, 2013) was acknowledged…
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Politics: Chinese migration
Chinese organisations increasingly operate across the borders of China, and growing numbers of people from outside China are coming to live there. Professor Frank Pieke believes these movements have a significant effect on central and local government policy in China.
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Chinese Premier Li Keqiang pays lightning visit to Leiden University
During his two-day visit to the Netherlands, the Chinese Prime Minister paid an unexpected visit to Leiden on 16 October. Li Keqiang spoke with Rector Carel Stolker, Chinese PhD candidates and students of China Studies.
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Coats, glasses and gloves, your last line of defense
Marie Curie once said: I have no dress except the one I wear every day. If you are going to be kind enough to give me one, please let it be practical and dark so that I can put it on afterwards to go to the laboratory.
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Global China’s Human Touch?
PhD defence
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Poster sessions
Speech Prosody 2024 includes several poster sessions, the description of which you can find below.