How can zebrafish research help understanding human diseases?

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…

We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…

Leiden University, the LUMC and Janssen have signed a partnership agreement stating that they will collaborate in different areas, including infectious disease prevention, clinical tests, drug production and e-health. By joining forces, the three partners will be able to provide better, more innovative…

What is the role of auxin in the initiation and process of somatic embryogenesis?

On Wednesday 25 January, the British Embassy, the Global Transformations and Governance Challenges (GTGC) programme at Leiden University and Women in International Security Netherlands (WIIS-NL) were hosting a round table with Professor Bina D’Costa to discuss the prevention of conflict related sexual…

On 2 and 3 October 2017, a delegation of the Child Law Department has participated in the 15th European regional conference of the International Society for the Prevention of Child Abuse and Neglect in The Hague.

An international team of scientists, including Xander Tielens of Leiden Observatory, has used space telescope Hubble and the ALMA observatory to show that UV radiation from massive stars can prevent planets from forming. The researchers publish their findings on 1 March in the journal Science.

The Metabolomics Facility of Leiden University is now officially in operation to prevent disease and to improve health throughout the human lifespan.

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

Can positive peer feedback break the cycle of negative self-relevant cognitive processes and reduce self-reported anxiety in early adolescents?

Bacteria in the teeth tell us a lot about nutrition and disease in our ancestors. It also tells us more about the immune system. This provides clues for treating modern diseases and allergies. For a long time archaeologists were irritated by tartar on the teeth of excavated skulls. They thought that…

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

Heart failure is a major health care problem with high mortality.

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.

Edwin Bakker is one of the speakers during the

Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.

Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

Source: Mol Psychiatry (2015)

The Social Resilience & Security interdisciplinary programme broadens its scope by embedding two research projects lead by Dr. Joanne Mouthaan. The projects adress suicide prevention skills and mental health of Ukraine refugees. Both projects will be integrated in the programme with the aim to improve…

What is the role of cell wall-deficiency in the persistence of tuberculosis?

As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.

Which plant leaf characteristics are involved in thrips resistance in tomato?

Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.

Professor Anne Meuwese is calling on governments to show more vulnerability when it comes to providing information about how they function.

Professor Tom Huizinga (LUMC) specialises in rheumatoid arthritis. He joined forces with alumni and the Natuurwetenschappelijk Gezelschap Leiden, a society that aims to share knowledge of the natural sciences and medicine, to explore the symptoms of the disease. With this form of arthritis the fluid…

Alastair Reed, Assistant professor at the Institute of Security and Global Affairs (ISGA) is interviewed by Devex, the media platform for the global development community.

Steering soil microbiomes for better crop quality: the holy grail to improve human health?

On 1 and 2 December 2022, Vincent Delhomme and Carina van Os participated (Europe Institute) in the workshop ‘The European Health Union - Setup, challenges and global outlook’, held at the Max Planck Institute for Comparative Public Law and International Law in Heidelberg. Vincent had the opportunity…

Memory loss and confusion are signs of Alzheimer’s disease. Physicists Serge Rombouts and Martina Huber have developed new methods to help medical science get to the bottom of this insidious disease.

Amanda Foks (Division of BioTherapeutics) has been awarded a Horizon 2020, ERA-CVD joint transnational cardiovascular research grant. She will lead a consortium consisting of early career European scientists (Dimitrios Tsiantoulas, Medical University of Vienna, Austria; Julia Polansky-Biskup, Charité…