Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.

Lecture

Lecture

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

The FIGON Dutch Medicines Days is the conference where partners from industry, scientific and professional associations, universities, and government present their findings in the field of innovative drug research & development, share new scientific insights and results, exchange experiences and information,…

Lecture

Lecture

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

During the guest lecture on 9 February, Jaap de Hoop Scheffer, Rob de Wijk and Frans Osinga discussed the situation in Ukraine and Taiwan. The crises in eastern Ukraine and the increasing tensions around Taiwan highlight the challenges the West faces in deterring aggression in the new era of key dynamics…

Nicole ter Laak (Master student Biopharmaceutical sciences) has won the third price of the “Dr Saal van Zwanenberg research price”. The award ceremony is on 14 November.

Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…

This March, Jara Bouma, Cas van der Horst and Laura Heitman from the Division of Drug Discovery and Safety and Laura de Paus, Richard van den Berg, Anthe Janssen and Mario van der Stelt from the LIC joined forces to determine how some drugs can specifically target the cannabinoid CB2 receptor (CB2R)…

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…

While all European nations have condemned the Russian invasion of Ukraine, there is one country Russia can still count on: Belarus. Russia even used its territory as a stepping stone for the invasion. We spoke with Matthew Frear, Assistant Professor and expert on contemporary Belarus, to shed light…

Lecture, Book Launch

Roundtable

Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.

Through its Demonstrator Projects, the Dutch Oncode Accelerator consortium provides grants for preclinical cancer therapy development. The first call for these projects is open until September 2025.

The Ministry of Health, Welfare and Sport (VWS) submitted Pharma-NL to the R&D program of the National Growth Fund, a 20 billion euro program of the Dutch government that intends to create long-term economic growth in The Netherlands.

Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.

If you’re unsure where to refer students to for well-being support, this page should help. It provides an overview of the support available at Leiden University.

Leiden University and African Child Policy Forum hold ‘ground-breaking’ workshop on antimicrobial resistance (AMR) and human rights in Africa

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

PhD defence

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

The decolonisation war in Indonesia was violent partly because the Dutch military operated on the conviction that ‘an uprising had to be forcibly suppressed.’ This what historian Christiaan Harinck from the KITLV discovered in his PhD research.

LUMC research has shown that women who previously had a miscarriage due to COVID-19 are not at increased risk of having another miscarriage or a stillbirth. Nor are preventive drugs needed during the pregnancy.

Emeritus professor Joke Bouwstra (LACDR) will receive this year's Dr Saal van Zwanenberg Ereprijs: a tribute to her years of fundamental research on the skin and the transport of drugs through the skin. This is the first time the prize has gone to a woman.

A memorable farewell symposium and a royal distinction: Professor Joke Bouwstra could not have completed her career at Leiden with more pleasure. On Friday, 14 June, she received a Royal Honor from Leiden Mayor Peter van der Velden, who appointed Bouwstra as a Knight in the Order of the Dutch Lion for…

Rebekka Grossmann awarded Gerald Westheimer Career Development Fellowship for research on the effects of migration on visual codes of global solidarity

On Friday the 29th of October, LACDR presented highlights of its research and teaching program during an online Lunchtime Talk session at the European Medicines Agency (EMA).

Willem Jespers was awarded the international prize, worth €10,000, for pharmacy and pharmacology from the Rottendorf foundation on October 13th 2023 at the University of Münster. He was recognized for his research in the field of computer-aided drug development and the prediction of drug toxicities.…

On the 8th of December 2021, Leiden Academic Centre for Drug Research (LACDR) organized “Circuit Topology 2021”, the first international symposium on circuit topology. The focus was on the mathematical notion of Circuit Topology, and its applications to physics, chemistry and biomedicine.

On 5 May we celebrate freedom, a basic human right that should not be taken for granted. We asked international students and staff what it means to them.

Patients with skin diseases such as eczema and psoriasis, sometimes spend a lifetime searching for the right medication. To help these patients faster and better, scientists across the country are joining forces. The Next Generation ImmunoDermatology (NGID) project, with LACDR professor Robert Rissmann…

A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.

Starting February 6, the Leiden interdisciplinary research programme Global Transformations and Governance Challenges (GTGC) will host a lunch seminar series on pressing global governance issues. The series will feature researchers from various disciplines. It promises to be a trove of inspiration and…

Debate

After an extremely painful conclusion, the Western allies have left Afghanistan and the Taliban have regained supremacy. How will Afghanistan move forward, and what does the departure mean for global relations? Rob de Wijk, emeritus Professor of International Relations and Security, analyses the failure…

Dutch troops, judges and politicians collectively condoned and concealed the systematic use of extreme violence during the Indonesian War of Independence. Historians have now shown how this could happen. ‘It was scandal management rather than prevention,’ says Leiden historian and research leader Gert…

Lecture, Seminar

Lecture, European Union Seminar

‘Everyone’s talking about it, everyone thinks everyone else is doing it, but the reality is disappointing,’ says biochemist Gerard van Westen in his 3 October University lecture in the Van der Werfpark. In the full marquee, he gets a laugh with this suggestion that artificial intelligence is comparable…

The Dutch Research Council (NWO) has, within the framework of Research along Routes by Consortia (NWA-ORC), awarded the research project Next Generation Immuno-Dermatology (NGID) with a prestigious grant of 11.7 MEuro. NGID is a nationwide, large-scale project to unravel novel biomarkers for six different…

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.

Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.