Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.

Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

War and peace studies. A topic that is more relevant than ever because of the war in Ukraine. In September, the MSc Crisis and Security Management (CSM) will start a new track: War and Peace Studies. CSM’s Programme Director, Ernst Dijxhoorn, discusses the new track, how it was created and what students…

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

This study by artist Jonas Staal explores the development of propaganda art from the 20th to the 21st century.

The Central Asia Initiative in Leiden was launched by the Leiden research area Asia Modernities and Traditions (AMT) in February 2015.

From the rise and fall of Egypt’s Muslim Brotherhood, to Islamic State’s attempts to create its own currency, to the dramatic return of the Taliban in Afghanistan, this edited volume from two leading scholars of contemporary terrorism assembles an enviable array of international experts to explore these…

This PhD project analyses the politics and aesthetics of depictions of torture in American and European ‘war on terror’ films.

The Dutch universities are shocked by the Russian invasion of Ukraine and empathise with all those affected by this act of aggression. Leiden University also calls for solidarity with and support for all those affected by the war.

The impact of a ceasefire shifts over the course of a conflict, as conflict party leaders learn more about each other’s military and political aspirations and adapt their use of ceasefires accordingly. That’s the key message of the dissertation of Valerie Sticher, PhD-candidate at the Faculty of Governance…

In health care, artificial intelligence is quite normal: it is used, for example, as an aid in making diagnoses. However, artificial intelligence is not yet used as much in drug development. A new prestigious partnership is therefore going to investigate how artificial intelligence can contribute to…

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

The impact of war extends beyond destroyed buildings and torn families. In bilingual Ukraine, the ongoing war with Russia is a major driver for increasingly discarding the Russian language. What does this mean for the position of Russian in Ukraine?

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

From studying molecules in the blood of corona patients to developing a new concept for vaccines. The Leiden Academic Centre for Drug Research (LACDR) has transformed many ongoing projects into Covid research projects. Hubertus Irth, scientific director of LACDR, talks about the role of his institute…

On Friday, November 17, 2017, Assistant Professor Jens Iverson provided the Keynote for the annual symposium by the Minnesota Journal of International Law: Jus Post Bellum: Justice After the War.

The American president Trump is considering military intervention in Mexico to get rid of the drug cartels once and for all, but Mexico is not interested in other countries' interventions. According to Jelle van Buuren, Assistant Professor at the Institute of Security and Global Affairs, Trump's much…

Actin and microtubules form cellular cytoskeletal network, which mediates cell shape, motility and proliferation and are key targets for cancer therapy. Changes in cytoskeletal organization correlate with proliferative capacity and invasiveness of cancer cells. These changes expectedly lead to altered…

Tensions ran high last week after China published a list on Wednesday of $50 billion in American products that would be hit by tariffs; a direct response to the United States' decision to implement $50 billion of tariffs on Chinese products. Could this be the start of a new trade war? And if so, what…

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.

On Wednesday 9 March, a Faculty meeting about the war in Ukraine was held for staff and students in the Lorentz Lecture Hall. By the time the meeting started at 17.00 hrs, the 220 available seats in the lecture hall had been filled mainly by large numbers of students.

Adopting a largely chronological approach, Gerrits links the historiography of post-war Europe and the major theoretical approaches to nationalism with analysis of key historical developments and events.

In an essay published in three prominent European newspapers, Professor Luuk van Middelaar takes a close look at Europe’s role in the Russian invasion of Ukraine. ‘Europe shows plenty of political energy, but what is still lacking is strategic cool-headedness, in facing a nuclear power.’

According to Russian propaganda Ukrainians are Nazis and people from the West are Satanists. Egbert Fortuin thinks we should take this propaganda seriously.

Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

International pharmaceuticals company Grünenthal is to open an innovation hub on the Leiden Bio Science Park. The hub will make it easier for scientists and drug developers to work together.

Professor Ian Lilley, the Faculty of Archaeology’s Willem Willems Chair in Archaeological Heritage, was invited by Her Excellency Mrs. Marion Derckx, Ambassador of the Kingdom of the Netherlands in Australia, to present the 2022 commemoration speech for Netherlands Memorial Day on May 4th at the Netherlands-Australia…

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

On 22 June, Najib Amin defended the thesis 'State-building, lawmaking, and criminal justice in Afghanistan: a case study of the prison system’s legal mandate, and the rehabilitation programmes in Pul-e-charkhi prison'. The doctoral research was supervised by Jan Michiel Otto and Pauline Schuyt.

Conference, Public Event

When Russia invaded Ukraine at the end of February, normal life there came to a halt. To ensure that affected students and researchers can continue their studies and work, professor Ellen Rutten (UvA) and assistant professor Dorine Schellens (Leiden) set up an international mentor network.

Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.

This book underscores the interplay between religion and politics (local and global) in the production, escalation, management, mitigation, and resolution of conflict.

Starting January 18, the online exhibition Images of the Indonesian War of Independence, 1945-1949 can be viewed via the UBL website. The exhibition is the result of a collaboration between the Royal Netherlands Institute of Southeast Asian and Caribbean Studies (KITLV) and Leiden University Libraries…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…

Can drug screening for tuberculosis treatment be made more efficient?

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.