905 search results for “michel als” in the Public website
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Technologies and social agency of painted plaster in the East Mediterranean Bronze Age
This project explored the role of material culture, in casu painted plaster and its technologies, in expressing dynamic social identities and in forging complex interwoven human relationships in the context of the Middle to Late Bronze Age of the Aegean and East Mediterranean.
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Información práctica
El X Congreso Internacional de la Asociación de Hispanistas del Benelux tendrá lugar en la Universidad de Leiden del 1 al 4 de noviembre de 2023. La conferencia será en modo presencial y se llevará a cabo en el edificio P.J Veth. El último día del congreso se llevará a cabo en la Haya.
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La Grande Roche excavation (Quinçay, France)
La Grande Roche is one of the rare archaeological sites that preserved a long sequence of deposits formed at the time of contact between late Neandertals and early Homo sapiens.
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Professional agency of beginning teachers
To what extent do beginning teachers use, create and claim agency at their school?
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Neandertal Legacy
The genetic material of currently living Europeans is partly of Neandertal origin. Were our ancestors successful because they were hybridising and interacting with the local populations they encountered when migrating into new places? Reconstructing our evolutionary trajectory is key for rethinking…
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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Sociabilidade do Brasil Neerlandês (1630 - 1654)
Painstaking research in Dutch and Portuguese archive materials, so far poorly assessed on the topic of social relations, reveals intense and intricate associations between different European individuals both in terms of ethnicity and social strata.
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nat. Comm. 2020
Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
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Minipigs as an Animal Model for Dermal Vaccine Delivery
Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.
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Global Music: recasting and Rethinking the Popular as Global
Vertrekkend vanuit een communicatief perspectief en concentrerend op mediatiseringsprocessen, formuleert deze dissertatie een alternatief voor het probleem van equivociteit binnen de studie naar populaire muziek.
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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Islamization Explored
Can we speak of a single Islamic discourse in fields like politics, militancy, economics, sustainable development, and the like, and what interaction does this Islamic though have with ‘Western’ thought?
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On the Spot: Panoramic Gaze on Istanbul, a History
This book was published in conjunction with an exhibition at the Pera Museum in Istanbul. It contains seven articles on the global panoramic visual history from the early modern to modern times and Istanbul's place within this history.
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The Ikūn-pîša Letter Archive from Tell ed-Dēr
This volume sees the publication of fifty-six early Old Babylonian letters from ca. 1880 BCE. They were found by legendary Iraqi archaeologist Taha Baqir in 1941 at the site of Tell ed-Dēr, ancient Sippar-Amnānum, in central Iraq.
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The Agro Pontino archaeological survey
ASLU 11
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The Middle Palaeolithic Occupation of Europe
Faculty of Archaeology, University of Leiden
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A community computational challenge to predict the activity of pairs of compounds
Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)
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Dutch Post-war Fiction Film through a Lens of Psychoanalysis
This week 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' by Peter Verstraten was published by Amsterdam University Press, the sequel to Humor and Irony in Dutch Post-war Fiction Film from 2016. Each chapter in his 482-page new study begins with a title of Fons Rademakers who made films…
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Modular curves, Arakelov theory, algorithmic applications
Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong
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Leiden Journal of Pottery Studies 22
Leiden Journal of Pottery Studies 22, 2006
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De eerste mensen in de Lage Landen
Nederland ligt in de periferie van het verhaal van menswording. De evolutie van onze familie vindt lang exclusief in Afrika plaats. En, als Europa eenmaal bewoond wordt door mensachtigen, ligt het zwaartepunt ten zuiden van onze streken. Toch heeft ons land een aantal interessante vindplaatsen en vondsten…
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Supporting medical teachers' learning: redesigning a program using characteristics of effective instructional development
In this research project characteristics of effective instructional development were identified that are appealing to medical teachers and relevant for medical education.
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.
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Profile 6. Developing a parcel based historical GIS of the Netherlands
Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…
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Meaning and R/S (religion and spirituality) in medical healthcare
The project focuses on communication processes regarding spirituality and existential issues in the medical health care in the Netherlands
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Pluricentriciteit in de taalgeschiedenis
On the 19th of April, Iris van de Voorde successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Iris on this achievement!
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Rooswijk 1740
Een scheepswrak, zijn bemanning en het leven in de 18de eeuw
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Two-Prover Bit-Commitments: Classical, Quantum and Non-Signaling
This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Data Science & Artificial Intelligence
De minor Data Science & Artificial Intelligence geeft een toegankelijke introductie tot de theorie en praktijk van datawetenschap en kunstmatige intelligentie. Studenten leren de basis van data-analyse en patroonherkenning in grote gegevensverzamelingen, hoe computers leren en ook het interpreteren…
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Gorlaeus Faculty Office
Einsteinweg 55, Leiden
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Update national FameLab competition
Biologists Michelle Spierings and Ryan Bogaars will both join the Dutch Final of the FameLab Competition on April 21st in Museum Boerhaave, Leiden.
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De aanpak van ondermijning en financieel-economische criminaliteit
Deze onderzoeksgroep richt zich op het thema ondermijning en financieel-economische criminaliteit, in het bijzonder de aanpak ervan op een aantal deelterreinen.
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Letters as loot
Linguistic research on a unique collection of Dutch letters allowed us to gain access to the every-day language of people from various walks of life. Private letters by men, women and even children have been elaborately explored in the Letters as Loot researchprogramme, initiated and directed by prof.…
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Special sessions
Speech Prosody 2024 includes seven special sessions. When making a submission, authors are asked to indicate whether they want their paper to be considered for a special session. You can find descriptions of each below.
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Scholarly publications
Below are some of the scholarly works published within the context of the Institutions for Conflict Resolution programme.
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Leiden heat of FameLab Competition
Biologists Michelle Spierings and Ryan Bogaars are 2 of the 4 winners of the Leiden heat for the international FameLab competition in talking science during a public presentation.
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Onzekerheid bij Professionals in Wijkteams
De decentralisaties van de zorg aan langdurig zieken en ouderen, jeugdzorg, en werk en inkomen die vanaf 2015 zijn doorgevoerd in Nederland hebben geleid tot een transitie van een centraal naar een lokaal stelsel van zorg en welzijn. Deze transitie beoogt zorg en ondersteuning dichter bij de inwoners…
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Science & Cinema
In films kunnen de meest wonderlijke acties plaatsvinden. Maar zijn die acties in de 'echte' wereld ook mogelijk? En in hoeverre houden filmmakers ons voor de gek? Tijdens het Leiden International Film Festival komen film en wetenschap samen.
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Youth and safety
Policy studies and interventions in the field of Youth
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Crisis management
Training and Exercising in Crisis management and Emergency Control
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Kennemerland in metaalvondsten
Duizenden metaalvondsten die door detectorzoeker wijlen Herman Zomerdijk zijn gedaan in de regio Kennemerland schetsen een uniek beeld van Noord-Holland door de eeuwen heen. Hij zocht en verzamelde decennialang historische metalen objecten in Noord-Holland en bouwde zo een unieke metaalcollectie op.
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Europese productnormen en privaatrechtelijke normstelling
On 10 June 2020, Gitta Veldt defended her thesis 'Europese productnormen en privaatrechtelijke normstelling'. The doctoral research was supervised by Prof. H.J. Snijders.
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Analecta Praehistorica Leidensia 43/44
The End Of Our Fifth Decade. Corrie Bakels & Hans Kamermans (eds) (2012)
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It's just a phase: High-contrast imaging with patterned liquid-crystal phase plates to facilitate characterization of exoplanets
This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.
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The End of our Third Decade (volume I)
Papers written on the occasion of the 30th anniversary of the Institute of Prehistory, Volume I.