Nietzsche's most famous and infamous book Thus Spoke Zarathustra is perhaps the most read, but probably also the least understood, book in Nietzsche's oeuvre. Nietzsche considered it his highlight. He called it a symphony, a holy book, a fifth gospel and even the greatest gift ever given to humanity.…

More than 30 members of Programme Committees, Faculty Councils and the University Council met online on 27 November with a mission: how can university co-participation work towards a more sustainable university in terms of education, research, and operations? The Leiden University Green Office and the…

Sound & Score brings together music expertise from prominent international researchers and performers exploring the intimate relations between sound, score and notation, and the artistic possibilities that this relationship yields for performers, composers and listeners.

We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

Mycobacterium tuberculosis (Mtb), the pathogen causing tuberculosis (TB), is the leader among all pathogens responsible for the most human deaths today and it is considered as one of the top 10 causes of death worldwide. There is an increasing occurrence of multidrug-resistant and even totally drug-resistant…

Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.

This dissertation offers a reconstruction of the propositional contents of the writings of Karl Popper, Leo Strauss, and Hannah Arendt while bringing these into discussion with their performative meanings, such as polemical forms of reasoning, analogical and metaphorical uses of language, and hidden…

PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.

Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

“Transitional justice” is a field of practice, policy and study that focuses on the ways that societies respond to legacies of large-scale atrocities though tribunals, truth commissions, reparations, and other mechanisms.

Associates of Leiden University Center for Intercultural Philosophy

This study is a critical discourse analysis of the misogynistic narratives shared by three incel violent extremists.

Dialogue is a multi-dimensional communication mechanism whose processes can only be examined by means of an interdisciplinary approach.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

How do humanitarian organisations adapt cyber incidents to their specific priorities and needs, and how can they adapt strategies of other organisations?

An Introduction and Field Guide, Second and Revised Edition (15 December 2014)

The Brazilian economy has long been defined by its enormous potential. Over the past 30 years, some of this has at last been realised. Latin America’s largest economy has rapidly risen in global importance while poverty at home has declined. Yet, despite periods of progress, Brazil remains prone to…

On 1 July 2020, Niek Strohmaier defended his thesis 'Making Sense of Business Failure'. The doctoral research was supervised by Prof. J.A.A. Adriaanse en dr. H. Pluut.

For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food. They found…

This PhD research aims to trace the impact of the Arab conquest, both immediate and long-term, on the material and social organization of Central Asia from 651 to 821 through an “urban change” perspective in four cities: Merv, Paikent, Balkh and Samarkand.

Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?

Leiden University Centre for Intercultural Philosophy (LUCIP) is a centre housed in the Institute for Philosophy at Leiden University.

Our research deals with the deep history of Europe and Eurasia, from the inception of farming up until the beginning of the Roman Period. This was a period in which key developments took place that had a profound impact on European landscapes and society until the present day. Our research and teaching…

An investigation into how racial stereotypes were created and used in the European Middle Ages.

We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

A GIS-based study for the reconstruction and interpretation of the archaeological datasets of ancient Boeotia

In what ways can a photographic practice act as a means to confront, or even undo, the various material properties of atmospheric enclosure that so clearly put our relationship with our environment under pressure? Is it possible to devise a set of critical and artistic strategies to comprehend the ways…

How did digital intermediality symbolise and facilitate the transfer of content from popular culture into policy statements and vice versa in the period between 1945 and the new millenium?

Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?

Linguistic Choices in the Contemporary City focuses on how individuals navigate conversation in highly diversified contexts and provides a broad overview of state of the art research in urban sociolinguistics across the globe.

Maps play a crucial role in our view of the past, yet few historians are sufficiently skilled in cartography to genuinely integrate maps into their research. This project breaks down the long-standing barriers between history and cartography by inviting emerging scholars (ResMA) to reflect on maps as…

Constitutional and administrative law covers a broad area of law. It provides the rules with which issues in society can be solved by government authorities.

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.

On 29 June 2017, Doris Dull-Zessner defended her PhD dissertation “Value Congruence in a Multinational Corporation”. The supervisors are Professor J.A.A. Adriaanse and Professor J.I. van der Rest.

Religious Studies at Leiden University allows you to study a broad spectrum of religions and their manifestations.

This special issue focuses on emerging trends in the implementation of the WPS agenda. In reviewing the resolution 20 years since the passing of Resolution 1325, Newby and O'Malley have highlighted the gaps in implementation.

Research is meant to generate knowledge, in a rational and sensible way. Many research methods exist to do this, and creativity is an important factor. Our mission is to explore creative, playful, unexpected, and unconventional forms of academic research.

In the study of West-East relations, difference often takes centre stage. This holds for both culturalist and postcolonial perspectives. By contrast, in my investigation of Netherlands-Iran political relations in the 1960s and 1970s, I will focus on the role of SIMILARITY. What lay at the root of the…

Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).

From deepfakes and disinformation to killer robots, surgical robots and AI lawmaking: AI (Artificial Intelligence) is changing our world. That raises the question whether this requires some form of regulation. At eLaw, the Center for Law and Digital Technologies at Leiden University, prof. Bart Custers…

Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.

Microbial Sciences' contribution to the Bioactive Molecules research theme is to discover new bioactive molecules and enzymes and unravel their mechanisms of action, regulatory networks, and the (bio)synthetic pathways required for their production.

The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?

Microneedles represent promising tools for delivery of drugs to the skin. However, before these microneedles can be used in clinical practice, it is essential to understand the process of skin penetration by these microneedles.

To argue that people can control the relative contributions of goal-driven and stimulus-driven processes to decision-making and action selection.

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

How can we implement the technique of pharmacological resting-state fMRI to improve the diagnosis of dementia?