How do plant defense genes get activated?

What are the conditions under which coercive diplomacy can compel a State to abandon its controversial nuclear (weapons) program? Based on the experience of the US coercive diplomacy against the nuclear programs of three countries, namely Iran, Libya and South Africa, Jean Yves Ndzana’s PhD research…

In the track Cybersecurity Governance, you will be familiarized with the breadth, depth and complexity of cybersecurity challenges. This track seeks to provide you state-of-the art with knowledge of governance and regulatory strategies available to address these challenges.

If you want to find out more about Leiden University, you can read our publications online or request a printed copy.

Which compounds and microorganisms that live near and inside plant roots are beneficial? Can we use this knowledge to improve the health and growth of crop plants?

How new media shape the communication strategies of the PRC’s official news agency Xinhua?

Vertrekkend vanuit een communicatief perspectief en concentrerend op mediatiseringsprocessen, formuleert deze dissertatie een alternatief voor het probleem van equivociteit binnen de studie naar populaire muziek.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

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Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Promotor: M. Ubbink, Co-promotor: G. Siegal

On the 4th of June, Andreas Joswig successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreas on this great result.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Central to this research is the Urban Future-project, which consists of a large archive of artworks made from 2002 until now.

This work provides a typologically oriented description of clause linkage strategies in Ket, a highly endangered language spoken in Central Siberia. It is now the only surviving member of the Yeniseian language family with the last remaining speakers residing in the north of Russia’s Krasnoyarsk pro…

The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Una Europa has identified and introduced six transversal themes as guiding principles for collaboration with the aim of supporting Una Europa staff and students to translate these themes into concrete actions.

‘We could share our knowledge more with others and apply it more widely,’ said Annetje Ottow, President of the Executive Board, while presenting the new Strategic Plan on the University’s 447th Dies Natalis. The new Strategic Plan therefore focuses on innovating and connecting, among disciplines and…

Tuberculosis bacteria and other intracellular pathogens use cells of our immune system as Trojan horses to spread into tissues. Annemarie Meijer, professor of immunobiology, explains how research into innate defence mechanisms using zebrafish inspires novel strategies for infectious disease treatmen…

For questions and remarks please contact the China Coordinator and Secretary of the China Region Group, Annemarie Montulet from the Strategy and Academic Affairs Directorate.

eLaw - Center of Law and Digital technologies from Leiden Law School, and the Vascular Surgery Department at Leiden University Medical Centre in the Netherlands, join forces to explore the use of AI for diabetes and secondary prevention of diabetic foot problems and won a prize for it.

When to launch a next-generation product in a competitive market and how much capacity should be allocated to it

What is the nature and scope of violence? Who offends, and in what context? Who are the victims? And how can we design suitable intervention and prevention strategies? In this track, you will be familiarised with the many faces of violent offending, to provide the knowledge and tools to understand,…

The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.

This volume, featuring sixteen contributions from leading Roman historians and archaeologists, sheds new light on approaches to the economic history of urban craftsmen and traders in the Roman world, with a particular emphasis on the imperial period.

This project aims at investigating the syntactic role of focus in ellipsis across languages.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

With the advent of multicore processors and data centers, computer hardware has become increasingly parallel, allowing one to run multiple pieces of software at the same time on different machines. Coordination of these pieces is best expressed in a coordination language as an explicit interaction protocol…

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer

What is the impact of Indonesia’s democratization process on everyday state-citizen relations?

This dissertation provides an account of polar questions in Italian dialects from a typological, theoretical and empirical perspective.

This dissertation focuses on the overt marking of φ features encoded on perfective active auxiliaries in a group of Southern Italian dialects.

In what ways can a photographic practice act as a means to confront, or even undo, the various material properties of atmospheric enclosure that so clearly put our relationship with our environment under pressure? Is it possible to devise a set of critical and artistic strategies to comprehend the ways…

NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…

This dissertation provides a description of the language Tadaksahak as it is spoken by the Idaksahak, a people group of about 30,000 living in the most eastern part of Mali and several isolated places in western Niger.

In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

How can Critical Raw Material policies/strategies be enhanced in the EU context?

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

This project investigates memorisation strategies that were employed in the fields of painting and calligraphy in imperial China, with a focus on the Ming (1368-1644) and Qing (1644-1911) dynasties.

Which traits and/or trade-offs determine benefits of being deciduous or evergreen?

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.