A liveable planet. More biodiversity. And resources which are being managed wisely. At the CML, we want to make an impact with our research and education. On this website you can read what we do to achieve that.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

PhD defence

Do large deletions represent a risk during CRISP/CAS9-mediated genome editing in plants?

Peak Performance: Collaborative Crisis Management Before and During International Summits. This comparative case study probes into conditions for collaborative governance in the security organisation of international summits.

Promotor: Prof.dr.ir. T.H. Oosterkamp, N. de Jonge

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Did early farmers deliberately use animal manure on their fields?

Since the adoption of agriculture people have cultivated fields. The project concerns all kinds of aspects related to raising crops.

Promotor: Prof.dr. G.P. van Wezel

Two Leiden research projects that focus on increasing the biodiversity of Dutch production systems for food and ornamental horticulture have started thanks to funding from the Dutch Research Council's KIC research programme.

Geology and Paleobotany of the Area surrounding the Archaeological Excavation at the Hazendonk River Dune (Western Netherlands).

Stratigraphy, Palaeoenvironment and Archaeology of the Middle and Late Pleistocene Deposits.

Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.

The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.

A special relationship between plants and fungi, which plays an important role in carbon storage in soil, has the potential to slow down climate change. However, the amount of carbon stored in soil is decreasing as a result of human activity. This is what researchers say in a publication in Nature Communications.…

Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…

The wealth of shoes, sandals and other footwear from ancient Egypt is poorly understood due to lack of research. This is remarkable, because from the very beginning of Egypt’s long history footwear served practical as well as more spiritual purposes.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

In the fall of 2021, Cleveringa professor Roméo Dallaire and world experts shared their thoughts about PTSD, children’s rights, war crimes, humanitarian law, and peacekeeping in a series of conversations about leadership and moral dilemma during times of conflict and crisis.

What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…

Following the Beirut explosion, BBC's podcast series The Foodchain explores the chemical that caused the blast: ammonium nitrate. A compound that is widely used to produce fertilizer. Professor of Environmental sustaibability Jan Willem Erisman tells about the effects of nitrogen on the environment.

How can we quantify the density of species within a community through environmental DNA concentrations?

Today’s socio-economic challenges aren’t new. In the centuries after the retreat of the Roman state people with different backgrounds and with different ways of life somehow managed to build and maintain a complex economic system in northern Gaul that would produce the ruling dynasties of Europe. By…

The worldwide race to the quantum computer is in full swing. This computer can take on computing tasks that we can only dream of today, such as finding proteins that can be used as medicines in seconds flat. Leiden physicists have discovered how the Majorana particle can be used as a building block…

PhD defence

Inaugural lecture

PhD defence

PhD defence

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.

Supervisor: P.J.J. Hooykaas

It is well-known that humans have significantly transformed ecosystems since their adoption of agriculture. However, in a deeper past, prehistoric hunter-gatherers may already have altered and modified their niche in ways that had major impacts on ecosystems.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

The book ‘Pesticides and the Environment’ gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Fieldwork is an essential part of this research and of course this part of the project is also a joint effort by citizen scientists and professional archaeologists. Discover when fieldwork will take place and how you can participate.

The overall objectives of my thesis are to investigate the dynamics of the sorghum root microbiome and to explore the beneficial effects of the root microbiome on sorghum growth and stress tolerance.

We aim to unravel the molecular mechanisms involved in the transformation of eukaryotic cells by Agrobacterium.

Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Paul Hudson, Associate Professor of Physical Geography at Leiden University College, examines human impacts on lowland rivers in his new book.