2,390 search results for “mathematics and statistical modelling” in the Public website
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mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling
Source: J Cheminform, Volume 7, Issue 1 (2015)
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Development of Generalized Squared Distance Logistic Model (GSDLM).
The objective of this project is the development of a new psychometric model, called the Generalized Squared Distance Logistic Model (GSDLM). This model is an evolution of older psychometric approaches (such as PARELLA, GHCM, and GGUM) and the Gaussian Ordination Models (GOMs) used in environmental…
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The parabolic Anderson model and long-range percolation
Promotor: Prof.dr. F. den Hollander
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Constraint-Based Analysis of Business Process Models
Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.
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Festive meeting: Vision on Statistical Science & info on the new Masters track
This September a new Masters Track
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Control theory methods for quantitative systems pharmacology models
Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.
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Why Leiden University?
The Computer Science and SCS master specialisation gives you the opportunity to combine fundamental research in computer science with different aspects of science communication.
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Why Leiden University?
The Computer Science and Education master specialisation gives you the opportunity to combine computer science research with an excellent education in becoming a teacher.
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FishForPharma: Training network on zebrafish infection models for pharmaceutical screens
How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
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Development of innovative engineered models for viral diseases
A main goal of MSBB research is to address the major bottle-necks in combatting viral diseases: the lack of experimental models that are representative of human pathology and are cost effective and versatile. Viral diseases such as those that cause viral hemorrhagic syndromes or severe acute respiratory…
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Highly sensitive analysis using 3D cell culture model
A research goal for ABS is to develop miniaturized platforms for research in (stem)cell, in-vitro systems and application in clinical and preventive research. Combined with the high throughput, this development will make it possible to study the dynamics of pathogenesis in human and cellular models…
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Proteochemometric modelling coupled to in silico target prediction
An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.
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Mathematical model helps to explain the formation of spine and ribs
Mathematical biologists from Leiden have developed a model that helps to explain how the spine and vertebrae, among other things, form during embryonic development. The same process, the other way around, plays a key role in cancer metastasis. Publication in iScience.
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Mathematics as weapon against desertification
PhD student Robbin Bastiaansen applies mathematics to get insight in practical problems. By comparing mathematical models with developments in existing ecosystems, he hopes to demystify the process of desertification. His research has been published in Proceedings of the National Academy of Sciences…
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Data Science
The ability to collect and interpret huge quantities of data has become indispensable to society and academia. Leiden University is a knowledge and expertise centre for data science that places the emphasis on interdisciplinary collaboration and innovation.
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic Species
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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Minipigs as an Animal Model for Dermal Vaccine Delivery
Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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‘Ūd Taqsīm as a Model of Pre-Composition
In this research project Rohana analyzes and reflects on taqsīm recordings by two leading figures of ‘ūd playing who were pillars of modern Arabic music, namely the Egyptians Muḥammad al-Qaṣabjī (1898-1964) and Riyāḍ al-Sunbāṭī (1906-1981).
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Alumni Career Event Methodology and Statistics Psychology
Alumni event
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Marc Spijker
Science
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Onno van Gaans
Science
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Hermen Jan Hupkes
Science
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Marcel de Jeu
Science
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Arjen Doelman
Science
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Frank den Hollander
Science
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Education
Methodology & Statistics offers bachelor's courses and a master's specialisation.
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Structural Health Monitoring Meets Data Mining
Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe
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Global Scenarios of Environmental Impacts with Structural Economic Models
To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.
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Invasive plant species, models for evolutionary change
Which traits did change due to the invasion process of plants and how do these traits contribute to the invasiveness of such species. What is the role of carbohydrate accumulation? What is the function of carbohydrate accumulation in plants? Is genetic variation depleted in invasive species under se…
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Bergson and the Aristotelian model of immanent teleology
This dissertation addresses the different use of the same philosophical model: immanent teleology. In this work Aristotle, the founder of the study of final causes, is put in relation with the modern French evolutionary thinker Henri Bergson, the philosopher of time. The dissertation tackles the two…
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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Contact
Contact details secretariat section Methodology & Statistics.
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In search of the atoms of mathematics
Combining geometry and number theory. That is what Dr Jan Vonk of the Institute of Mathematics receives a Vidi grant for today. ‘By fusing these two disciplines we may be able to solve a century-old mathematical problem.’
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Lattice models for Josephson junctions and graphene superlattices
In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.
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Deconstructing stability. Modelling changing environmental conditions and man-land relations in the Pleistocene landscape of Twente (2850 - 12
The project Deconstructing Stability aims to improve reconstructions of late prehistoric landscapes and predictive models for the purpose of archaeological heritage management.
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About Faculty of Science
The Faculty of Science is located at the Leiden Bio Science Park. It was founded more than two centuries ago and currently, more than 8000 people are working and studying at the eight institutes.
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Why Leiden University?
The programme will give you the opportunity to choose from a broad range of topics to study. You will be part of an international multidisciplinary research team at our institute.
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Death of Mathematics student Willem Obbens
With dismay we took note of the sudden death of Willem Obbens, student and student assistant in Mathematics, Leiden University.
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Contact
The programme group Research Methods and Statistics is part of the Institute of Education and Child Studies. This group is located in the Faculty of Social and Behavioural Sciences of Leiden University near Central Station.
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New section makes statistics understandable
‘Statistics? I hated that hard subject in school’, statistician Sanne Willems is often told. And that is a pity, she thinks, because statistics doesn’t necessarily have to be difficult. Together with two former fellow students, she set up a Statistics Communication section for good communication on…
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Mathematical Institute cooperates with UWV
Marta Fiocco, associate professor at the Mathematical Institute of Leiden University, has signed an agreement with the UWV (the administrative authority that implements employee insurances and provides labour market and data services) to work with their data in the research project
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About the programme
The master’s programme offers two research-oriented specialisations where you can focus on Algebra, Geometry and Number Theory or Applied Mathematics. You can also combine Mathematics with education, management or science communication.
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Why the mathematics of operations research is so fascinating – even for a layperson
Floske Spieksma will give her inaugural lecture as Professor of Mathematics of Operations Research on 1 September. A discussion about mathematical models, Venezuela, trembling knees, being the only woman, casinos, intuition and above all loving your job.
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Paul Nieuwbeerta affiliated professor at Statistics Netherlands
From April 2022, Professor Paul Nieuwbeerta will be working one day a week as affiliated professor for Statistics Netherlands (Centraal Bureau voor de Statistiek (CBS)). He is Professor of Criminology at the Institute of Criminal Law and Criminology, Leiden University.
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt