697 search results for “fmri use” in the Public website
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Ellen van Reuler
Faculteit der Sociale Wetenschappen
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Karsten Wentink
Faculteit Archeologie
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Using zebrafish to target the Achilles’ heel of cancer
Exploiting metabolic vulnerabilities to identify anticancer compounds in zebrafish synthetic lethality screens.
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SAPPAO - Optimizing the flight times of airplanes using data science
The SAPPAO project aims to optimise the accuracy and reliability of predicting scheduled flight times. The full name of the project is 'A Systems Approach towards Data Mining and Prediction in Airlines Operations'.
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Unraveling cross-presentation pathways using a chemical biology approach
Is it possible for sugar patterns on cells to activate the immune system to combat cancer?
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Using smartphone behaviour to understand healthy ageing and neurological disease
Leiden University researchers and their collaborators report the development of new research frameworks that use day-to-day smartphone behavior gathered from a large sample of healthy people to help understand aging, and how aging alters with epilepsy and stroke. These reports occupy two back-to-back…
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Peptide amphiphiles and their use in supramolecular chemistry
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Anxiety traits are visible in the brain
Questionnaires or concentration tasks can be used to screen for anxiety, but so too can EEG recordings – at least indirectly. The frequent mind wandering of anxious people can also be seen on MRI scans. These are just some of the findings of clinical neuropsychologist Dana van Son. PhD defence on 24…
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Replacing fear with something new: Using novelty to unlearn fear.
This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.
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Cognition in the digital environment laboratory
To develop a new generation of brain science (and train scientists) focused on explaining complex real-world behavioural patterns.
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Figuring rural development: concepts and cases of land use, sustainability and integrative indicators
Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet
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Our team
Researchers from five different discplines work together in this interdisciplinary initiative.
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Intradermal delivery of nanoparticulate vaccines using coated and hollow microneedles
In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken
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Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
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Freedom on the Offensive: Human Rights, Democracy Promotion, and US Interventionism in the Late Cold War
In Freedom on the Offensive, William Michael Schmidli illuminates how the Reagan administration's embrace of democracy promotion was a defining development in US foreign relations in the late twentieth century.
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Why It Is Wrong to Use Student Evaluations of Professors as a Measure of Teaching Effectiveness
In this article, Eamon Aloyo argues that university supervisors should not use student evaluations of teachers as a measure of teaching effectiveness.
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Navigating the cross-contextual media landscape: Children’s digital media use and their social development
For this project we delve into children's digital media use during the transition from kindergarten to group 3 and investigate its impact on their social development.
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The use of self- and peer assessment with video in courses on professional practice
How can video on professional practices in university courses be used in a valid and useful way for assessment and feedback?
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Evaluating European imports of Asian aquaculture products using statistically supported life cycle assessments
Promotor: Prof.dr. G.R. de Snoo
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Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice
In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.
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Using a practical teaching model by beginning teachers learning to design lessons.
Beginning teachers often experience difficulties making activating lessons. This study investigates how and if the practical teaching model can offer them a hand in learning to design lessons.
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Language prescriptivism: Attitudes to usage vs. actual language use in American English
On December 18th, Viktorija Kostadinova succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Viktorija on this great result.
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Effect of Nanoparticles on Microbial Catabolism and Community Structure using Biolog techniques
1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?
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The reconstruction of the codex Añute palimpsest using hyperspectral imaging data
A technique originally developed for satellite imaging can now be used to recover pictographic texts from underneath the surface of a five hundred year old Mexican manuscript.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer
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Proper and improper uses of MCDA methods in energy systems analysis
In this article, Marco Cinelli, assistant professor at Leiden University College The Hague, examines proper and improper uses of Multiple Criteria Decision Analysis (MCDA) methods in energy systems analysis.
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Faithful Protection: The Use of Scripture in Egyptian Amulets (7th – 12th Century CE)
A selected group of unpublished amulets from various collections in the world will be studied and edited.
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Do internationally adopted children in the Netherlands use more medication than their non-adopted peers?
Adoptees in the Netherlands generally do not use more medication than their non-adopted peers.
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Surface Reactivity of Activated CO2 Selective use of energy in splitting CO2
Juurlink
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From Descriptive to Predictive Pharmacology in Children using Semi-Physiological population modelling
An integrated approach of physiological concepts, advanced statistical approaches and large clinical datasets.
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Digging in documents: using text mining to access the hidden knowledge in Dutch archaeological excavation reports
The archaeology domain produces large amounts of texts, too much to effectively read or manually search through for research. To alleviate this problem, we created a search system (called AGNES), which combines full text search with entity and geographical search.
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Microbial communities in Pampa soils; impact of land use changes, soil type and climatic conditions
Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae
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Using cryo-EM methods to uncover structure and function of bacteriophages
Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Development of an in vitro vascular network using zebrafish embryonic cells
How can we culture an artificial vascular network to support tissue development ex vivo?
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Plant occurrence in space and time: the importance of land use, habitat structure, and pollination mode
Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.
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The use of animal manure by prehistoric and early medieval farmers
Did early farmers deliberately use animal manure on their fields?
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Development of an in vitro vascular network using zebrafish embryonic cells
One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.
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Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
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enhanced by prenatal video-feedback: a randomized controlled trial using ultrasound imaging
The transition period in which men become fathers might provide an important window of opportunity for parenting interventions that may produce long-term positive effects on paternal care and, consequently, child development. Existing prenatal programs traditionally focus on maternal and infant health…
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Hieroglyphs, Pseudo-Scripts and Alphabets: Their Use and Reception in Ancient Egypt and Neighbouring Regions
The Egyptian hieroglyphic script was exceptionally versatile, as becomes clear when studying its multiple uses both within Ancient Egypt and beyond its borders.
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Conspiracy thinking and social media use are associated with ability to detect deepfakes
Deepfakes are videos that have been manipulated to replace one person’s likeness with that of another. They can be difficult to distinguish from authentic videos. In our study, we found that people who score high on conspiracy thinking and people who use social media more are better at distinguishing…
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Word processing in languages using non-alphabetic scripts: The cases of Japanese and Chinese
This thesis investigates the processing of words written in Japanese kanji and Chinese hànzì, i.e. logographic scripts.
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The use of Deep Learning in the automated detection of archaeological objects in remotely sensed data
Generally the data from remote sensing surveys - the scanning of the earth by satellite or aircraft in order to obtain information about it - is screened manually in archaeology. However, constant monitoring of the earth's surface causes a huge influx of data of high complexity and high quality. To…
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Teachers' use of progress data in planning and evaluating instruction for students with learning disabilities
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.