This pioneering project will answer this question by examining migrants through the eyes of the courts between 1600 and 1900. It aims to reveal patterns of continuity and change in: 1. Treatment of migrants by criminal courts; 2. Violence and conflicts between migrants and native born.

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

In the specialisation Health and Medical Psychology, part of the Master in Psychology, you will acquire knowledge on clinical and scientific topics in health promotion and disease prevention as well as practical training on clinical skills and behaviour change.

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

PhD defence

Peter Rodrigues, Professor of Immigration Law, has been appointed as a deputy member of the Netherlands Institute for Human Rights for a period of eighteen months.

Professor Tom Huizinga (LUMC) specialises in rheumatoid arthritis. He joined forces with alumni and the Natuurwetenschappelijk Gezelschap Leiden, a society that aims to share knowledge of the natural sciences and medicine, to explore the symptoms of the disease. With this form of arthritis the fluid…

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

Subproject of

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

The chairman of an allotment garden association in the Dutch town of Helmond has come under fire as its regulations contain a controversial rule that a maximum of five plots can be rented by one single nationality.

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We work on clinical problems that require further mechanistic understanding and strive for ultimate benefit to patients.

Four Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Academic Research (NWO).

Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.

PhD defence

Which criteria do ED patients and therapists evaluate as most relevant for recovery? Do patients and therapists differ in their evaluations? Do eating disorder patients differ from a healthy control group in their scores on the Recovery Scale?

Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments. We apply our technology and methods to find biomarkers for key disease pathways and toxicity in clinical studies and in…

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.

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The modification of risk factors and related health behaviors lies at the very core of adequate cardiovascular risk management, yet evidence shows that the majority of people with cardiovascular disease (CVD) fail to achieve a healthy lifestyle in the long term. The main objective of this project is…

In the specialisation Clinical Neuropsychology, part of the Master in Psychology, you will focus on fostering clinical and scientific skills based on a solid theoretical background as well as practical training in neuropsychology and (clinical) neuropsychological research.

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

PhD defence

Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.

Development of Comprehensive and High-throughput metabolomics techniques and Clinical applications of (pharmaco)metabolomics

Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…

In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).

Only one in five young people with emotional health problems such as an anxiety disorder receives appropriate professional help. GPs often fail to properly recognise the signals in children and young people, according to psychologist Semiha Aydin. How can we improve this? PhD defence 23 February.

Toward optimal measurement and greater understanding of youth cognition in school refusal and cognitive behavioural therapy outcome

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Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Leiden University social scientists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.

This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

Analysis of neuroimaging data requires multiple steps where statistics play a crucial role. The MRI methods research group develops new statistical methods that are accurate, transparent and easy to use.

Leiden University neuropsychologists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

Commercial enterprises who want to make use of the expertise and facilities are referred to LAB , the commercial unit responsible for specialized laboratory work.

We carry a profound responsibility for our research animals and strive to provide them with the best possible quality of life. In our studies, we make every effort to avoid and minimise discomfort for the animals. Below, you can learn more about how this is put into practice.

Grants awarded to molecular physiology research

While many healthcare professionals indicate that they frequently use placebo effects and their mechanisms, there is little formal training on how to deal with placebo and nocebo effects in clinical practice. This project aims to address this gap between scientific knowledge on placebo and nocebo effects…

We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…