Already during their bachelor’s programme, students in Pharmaceutical Sciences are presented with challenging projects. One of these is the Bachelor Research Assignment (BOO in Dutch), which is often their first real experience with scientific research. This means a lot of responsibility and failures,…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

Working towards resilient communities, transparency in science and connecting with the employment market – these are the three key themes being addressed by the departments of Social and Behavioural Sciences at Dutch universities. On 11 February, they presented a joint sector plan to Marcelis Boereboom,…

Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…

Dear Sir or Madam? Many colleagues think that sounds out of date. That is why the hundreds of thousands of automated messages sent by university help desks every year will now include a gender-neutral salutation. This change is an extensive but important ICT job, says product owner Julian van der Kr…

It often takes longer for women with heart problems to get the right diagnosis. In her Annie Romein-Verschoor Lecture, Professor Hester den Ruijter will talk about how hormones influence the heart and the importance of medical research that focuses specifically on women.

Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…

It is often thought that immigration threatens the solidarity on which redistribution relies. But looking at the post-war period, PhD candidate Emily Anne Wolff finds that this is not the case.

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…

Martina Huber, Jacqueline Labra Munoz research Alzheimer's disease. They study ferritine, iron storage in the brain. An inbalance of iron could play a role in this form of dementia.

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

Suddenly getting lost, failing to recognise family members, or forgetting words and names are well-known symptoms of Alzheimer's disease. Psychologists have now discovered that the disease also manifests in more subtle ways: through the rhythm of finger tapping.

Bird, butterfly, fish: when you look through a children’s book, you usually don’t think about the fact that humans divided these animals, depicted in bright colours, into categories. Yet, this division has been discussed for centuries. In her PhD dissertation, Didi van Trijp shows how natural scientists…

In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…

For the International Day of Women and Girls in Science, women students and researchers from physics talk about what inspires them about their work. From quantum to cosmology and biophysics, their curiosity about how nature works is what connects these women. What do these 5 scientists want to share…

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

What will it be like to study at Leiden University in 2075? Ten surprising, artistic uni-visions could be brought to life. It’s up to you to vote for your favourite.

The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.

Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

Her office is a bit tucked away in a corner of the building, but her department is always buzzing with activity. Since May 2024, Renate Rijbroek has been our new Head of Facility Management. There was no slow start: ‘We are working hard towards the official opening in September.’

Plants can’t run away from enemies. Still, it would like to keep life-threatening herbivores at a distance. This can be done with odours. Klaas Vrieling of the Institute of Biology Leiden found out with his team how plants change odour production to keep the munchers at a distance.

What does the future of quantum look like? Vedran Dunjko (Assistant professor at LIACS and LION) is co-founder of the applied quantum algorithms (aQa) leiden interdepartmental initiative research that will investigate this. They are part of the Quantum Delta NL consortium that was recently awarded substantial…

Haar hele leven wilde de geadopteerde Cindy Huijgen terug naar haar geboorteland China. Inmiddels is de alumnus Chinastudies en Journalistiek en Nieuwe Media er correspondent.

We need to dispel the arrogant and misguided idea that modern humans are superior to earlier human species. It is thanks in part to all our predecessors such as Neanderthals that we are who we are today. This is what Marie Soressi, Professor of Hominin Diversity Archaeology, will argue in her inaugural…

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

In medical and psychological sciences, little research has been specifically conducted on women. Hormonal fluctuations were considered too intricate. Yes, research into sex and gender differences is complex, acknowledge neuroscientists Ellen de Bruijn and Lara Wierenga, but that’s precisely why it's…

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…

The annual LION Image award goes to the 30 micrometer long 3D printed microboat image that went viral earlier in October 2020, submitted by Rachel Doherty of the Daniela Kraft lab.

A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.

The university is launching a campaign to focus extra attention on our smoke-free university locations. The University is using aptly named cigarette barrels to try to show clearly just how many cigarette filters are being saved from the environment. How harmful are these cigarette filters to the e…

Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

Prof. Andrea Evers is a health psychologist who studies the role of behavioural factors in health and disease. As a Medical Delta Professor, she is now affiliated with Leiden University, TU Delft and Erasmus University. In that position, she conducts research at the intersection of various disciplines.…

Give organisms like plants and animals the freedom to move, interact and meet their own needs, and they will thrive on their own, says Professor Geert de Snoo. Our interference often ends up doing more harm than good.

Moving an electron microscope of 2000 kg is a delicate challenge. The highly sensitive instrument needed to be moved to a new measurement hall, but even a tiny bump could damage it. After a few nerve-racking weeks of preparing the move and reinstalment, the researchers finally have a verdict: the instrument…

Which questions should you take to HR, and when should you contact the PSSC? How exactly does leave work, and what about career development? In this column, an HR colleague answers a different question each time. Anna is an HR advisor and knows everything about being pregnant while working.

Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…

‘By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia,’ predicts Professor John van Noort. Together with four leading biophysics research groups, he has written a review article in…

Democracy may lead to more deforestation in the tropics. So write environmental scientist Joeri Morpurgo and his colleagues in the prominent scientific journal Biological conservation. They found that competitive elections are associated with more loss of tropical rainforest than elections without competition.…

How do opinions form and change in large groups of people? That's not just a sociological question, it's a mathematical one. PhD candidate Federico Capannoli studied opinion dynamics. He defended his thesis on November 19.

Fossil teeth can preserve remarkable information, much like a biological identity card with data about the lives of individuals tens of thousands of years ago. By analyzing teeth, a new study published in Science Advances reconstructed the life history of four straight-tusked elephants (Palaeoloxodon…

While the Netherlands was in lockdown because of the coronavirus, PhD candidate Koen Rijpkema began his research into the same virus. In the lab, he developed molecules that can inhibit an important viral enzyme.