523 search results for “stam cell biology” in the Staff website
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Spatio-temporal aspects of antigen cross-presentation in dendritic cells
PhD defence
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Monolayer Graphene as a Proton-Selective Membrane for Direct Methanol Fuel Cells
PhD defence
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Synthesis and application cell wall glycopolymer fragments from Staphylococci and Enterococci
PhD defence
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Integrating cellular and tissue dynamics with cell fate decisions through computational modeling
PhD defence
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‘Most students are convinced that statistics is not for them. I am here to convince them otherwise’
'Frans Rodenburg is an excellent teacher who is able to convey difficult information,' say his students. In his statistics classes, he wants to make students enthusiastic for his beloved subject. 'Most students are convinced that statistics is not for them. I am here to convince them otherwise.' Rodenburg…
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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Not wrapping but folding: Bacteria also organise their DNA (but they do it a bit differently)
Some bacteria, it turns out, have proteins much like ours that organise the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for Biology. The discovery helps us better understand…
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Chao Du
Science
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Tom van der Wel
Science
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Pingtao Ding
Science
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Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
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Improving the treatment of pathogenic fungi. ‘The process is working, but not that well…’
Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…
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Several Leiden Science students excel and win KHMW Young Talent awards
A true shower of awards for students from the Faculty of Science during the annual KHMW Young Talent Awards ceremony. On Monday, 25 November, no less than nine first-year students received a prize for the best academic results in their first year. In addition, there were graduation prizes for master’s…
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
PhD defence
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Unique ‘penis plant’ flowers at Hortus
Amorphophallus decus-silvae, or the ‘penis plant’ as it is known, has just flowered at the Hortus botanicus. It flowered for two days, and then the pollen, which the male flowers produced was collected. As far as the plant experts at the Hortus can tell, this was just the third time that this species…
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Graduate School
Welcome to the Graduate School of the Faculty of Humanities. On this website you'll find a wide range of information you might need as a PhD candidate. If you have any further questions, please contact the Graduate School Office.
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BioTherapeutics in new national AtheroNeth consortium
The Dutch Heart Foundation will fund a new nation-wide consortium, AtheroNeth, consisting of preclinical and clinical scientists in the field of atherosclerosis research. AtheroNeth aims to identify novel biomarkers that can be applied to stratify patient groups at risk for acute cardiovascular events…
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…
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Nobel Prize winner visited Leiden: 'We have hosted a scientific rockstar'
On 28 September the famous chemists Carolyn Bertozzi visited Leiden University to speak at the LED3 seminar. Just one week later, she was announced winner the 2022 Nobel Prize in Chemistry. Leiden chemists Sebastian Pomplun and Hermen Overkleeft are fan: ‘We are extremely honoured to have hosted this…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Special nanoparticles for cancer therapy! Will you help?
Developing a better treatment for patients with head and neck cancer, that is what Binanox, The 2022 iGEM Leiden team, want to achieve. They hope to raise at least 10,000 euros for this cause. Support their crowdfunding campaign today.
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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How to make an old antibiotic a hundred times more potent
Nathaniel Martin, Professor of Biological chemistry, wondered what would happen if you take an antibiotic that has been known for 70 years and try to improve it with the latest tools of modern chemistry. Turns out it can become up to a hundred times more potent and prevent the growth of some drug-resistant…
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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New professor Luca Giomi creates his own physics of living systems
Swarms of drones, pedestrians or the cells in your body. Those are all examples of active matter: materials whose building blocks can move autonomously. That’s what Luca Giomi studies. Giomi has been appointed Professor of theoretical physics in the area of soft matter and biological physics at the…
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OSCARS Grant Awarded for BIO-CODES Project
Dr. Sylvia Le Dévédec has been awarded an OSCARS grant for the project BIO-CODES. OSCARS, a four-year Horizon Europe initiative, promoting the adoption of Open Science in Europe by building on the successes of world-class European Research Infrastructures (RIs) in the ESFRI roadmap and beyond. Among…
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Hoe meer tijd, hoe beter de nier
Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.
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What DNA in droppings can reveal about an animal’s diet
Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.
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silver clusters as a multi-functional tool for applications in physics, biology and medicine
PhD defence
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Is a cancer pill a matter of time?
A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.
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Embryos of the bitterling perform a somersault. This teaches us something new about natural selection
Even embryos can become embroiled in an evolutionary arms race with another species. Leiden biologists demonstrate this with larvae of the rosy bitterling that parasitize the gills of freshwater mussels. They published their research on February 19 in PNAS.
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Annual Lecture by Megan Vaughan: Africa in the time of Coronavirus. Biology, history and politics
Lecture
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In Memoriam - Bente Hilde Bakker
Recently, our respected and talented former colleague Bente Hilde Bakker passed away after a long and brave fight with illness. She received her mathematical training at the Vrije Universiteit in Amsterdam and also obtained her PhD there under the supervision of Jan Bouwe van den Berg and Robert van…
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European grants for research on ultrathin membranes and the biological clock in bacteria
Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.
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ESOF ‘Art Exploring Science’ session will connect art and science
How can we view societal challenges from a different perspective? At the EuroScience Open Forum (ESOF), Robert Zwijnenberg, Emeritus Professor of Art and Science Interactions, will call for more collaboration between artists and scientists.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Chemotherapy without side effects? It’s possible, with light
Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.
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Revolutionizing plant protection strategies: Ding lab receives 2.4M grant to investigate plant immunity
Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…
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PhD candidate from Leiden presents international student event
From pipetting in the lab to shining in front of the camera at a global student event. With 8.000 viewers watching the livestream, Marjolein Crooijmans presented the iGEM Giant Jamboree in Paris.
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A lifeline for Leiden research – TB solution a step closer thanks to this Indonesian university
Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…
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Why arteriosclerosis looks like an autoimmune disease
Arteriosclerosis bears great similarities to autoimmune diseases. Researchers from Leiden University show this in a new study they published in the renowned scientific journal Nature Cardiovascular Research. 'This discovery suggests that treatment methods for autoimmune diseases might also be effective…
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Sarah de Rijcke participates on a $1.2M grant awarded to DORA to accelerate research assessment reform
The project will further the development of policies, practices, and capabilities in responsible academic career assessment.
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New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
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Heineken Young Scientists Award for three Leiden researchers
Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.
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How touchscreens and eye trackers can tell us something about the dating life of orangutans
Aesthetic attraction plays a big role in orangutans’ mate choice, behavioural biologist and PhD candidate Tom Roth has observed. But to discover just how big that role is, more research is needed into the emotions of the great apes.
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Human noise makes cod inactive. When it gets quiet again, they take off
She narrowly defied bureaucracy and spent days angling for cod. In the North Sea, marine biologist Inge van der Knaap discovered that noise significantly disturbs fish behaviour. ‘There is now a lot of attention for underwater noise.’
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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ICT-contact persons
For each university unit, the ICT Shared Service Centre (ISSC) has an appointed ICT contact person responsible for applying for ICT facilities for research, teaching and operational management.