Health Data Science Leiden University

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

It is with great pleasure that we present to you the second volume of Inter-Section, published in 2016.

Curved single crystals provide variable, but well-defined surface structures.

We are developing biology-driven platforms to measure metabolites based on liquid chromatography-mass spectrometry (LC-MS), gas chromatography-MS (GC-MS), and capillary electrophoresis-MS (CE-MS).

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

The correctness of computational systems is of great importance to our society, since it becomes ever more reliant on the benefits of computing.

The Centre for Professional Learning (CPL) develops in-depth and challenging programmes for higher educated professionals.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

The goal is to establish an intuitive search and querying service that allows researchers to quickly retrieve the most valuable digital resources, in order to allow them to integrate and synthesise the results into a coherent narrative of the past. The current focus of the project is to implement…

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

Promotor: M.A.G.J. Orrit

We study the dynamics of individual emitters in micro cavities.

Radio jets are important to the evoultion of galaxies. However, it is still not fully understood how a radio jet can be triggered.

Multi-Angle Dynamic Light Scattering (MADLS) is a technique that is used to determine properties of particles in suspension. The measurements give the hydrodynamic size distribution of individual particles as well as particle clusters, and assists in the interpretation of the stability of the particles…

The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

The central research question focuses on identifying shifts in the urban social network in terms of private, semi-public and public space by means of mapping the spatial distributions of wells and cesspits in the town of Haarlem in the course of the pre-industrial period (1200-1800). Shifts may be indicative…

This dissertation provides a grammatical description of the Awjila language, a small Berber language spoken in the Libyan oasis of Awjila.

In the overview below you can find the LUC Newsletters that were send out during block 3 and spring break in semester 2 of academic year 2019 - 2020.

It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…

The main purpose of DNAmarkerpoint is to better understand the ecology, evolution and biodiversity through the study of ancient- and modern DNA.

The Data Science Research Programme at Leiden University combines data science with PhD projects in a wide range of disciplines. The programme has been running for over two years, and is producing the first astonishing results. A number of PhD candidates talk about their experiences and research bel…

Knowledge and culture subproject 1:

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Intelligent machines are going to make ethical decisions too. Should a self-driving car be allowed to slam into pedestrians to save its passengers from a head-on collision? Should a negotiation app be able to detect stress in your opponent’s voice? And who makes these decisions: the user, the system’s…

Speech Prosody 2024 includes three exciting tutorials. Below you will find the description as well as the recording of all three of them.

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.

What workflow of non-destructive techniques provides accurate, valuable data to improve our understanding of Caribbean archaeological landscapes? How were Amerindian settlements configured?

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars (exoplanets). They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems. This way they address…

Metabolomicshas emerged as an important discipline to study molecular and cellular processes in living cells and organisms with the ultimate aim to obtain an answer to a given biological/clinical question.

If researchers make their data FAIR, computers can link large quantities of data and identify patterns, thus greatly accelerating the process of arriving at new insights. In Leiden, the birthplace of ‘FAIR data’, Professor Barend Mons explains the meaning of this term.

MRFM combines the principles of magnetic resonance and atomic force microscopy.

This project aims to improve understanding of, and responses to, the phenomenon of lone actors through analysis of comprehensive data on cases from across Europe.

Researchers of the National University of Singapore and Leiden University have discovered that chimpanzees and bonobos share the contrasting colour pattern seen in human eyes, which makes it easy for them to detect the direction of someone’s gaze from a distance.

We explore the possibilities to combine magnetic resonance techniques with atomic force microscopy together in a single microscope: the MRI-AFM, also called Magnetic Resonance Force Microscopy (MRFM).

Detecting and combatting crime is becoming increasingly complex. Security is high on the national and international agenda. The master’s programme Crime and Criminal Justice in Leiden provides the skills to face these challenges.

Browse the latest articles and issues of Inter-Section.

PhD defence

PhD defence

PhD defence

PhD defence

Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.

Studying the underlying principles of the nature of language.

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Promotor: M.A.G.J. Orrit

Brain development in children with an extra X chromosome as compared to children with autism: evidence from MRI