419 search results for “neurodegenerative disease” in the Staff website
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Faculty of Humanities joins 'Hidden Disabilities Sunflower'
A hidden disability can make studying a considerable challenge, partly because of the disability itself, but also because others may not realise that extra support is justified. To overcome this problem, the Faculty of Humanities is introducing the Hidden Disabilities Sunflower.
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Video lecture: What is cancer?
Cancer is still one of the most common diseases in the world. What exactly is cancer and will we one day be able to cure everyone? In a video from the Universiteit van Nederland Noel de Miranda (Tumour Immunology, LUMC) tells you about his research on new treatments.
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Dental remains shed light on drug use in 19th century Dutch village
Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.
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Why we should handle antibiotics with care
More and more people worldwide have infections caused by bacteria that are resistant to many types of antibiotic. Why is this and how big of a problem is it?
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‘A few nerves before lectures show that my work matters’
Giving an incorrect answer as a student in a packed lecture hall can be nerve-wracking. But with Pharmacology teacher Rob van Wijk, you don’t need to worry about that. ‘He creates a comfortable and safe atmosphere,’ his students say. They have nominated him for the Leiden Science Teacher Award.
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Quality of life is sometimes more important to the elderly than a cure
Geriatrics needs to radically change. This is what Simon Mooijaart will say in his inaugural lecture.
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Skin researcher calls for multidisciplinary collaboration: ‘I want to pool expertise’
In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…
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Carrot or stick: which is better motivation to exercise more?
Free cinema tickets or a step tracker paid for by your health insurance. Some insurers offer rewards to promote healthy behaviour. But does the threat of losing something like a deposit work better? And what do patients think? This is what PhD candidate David de Buisonjé researched.
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A good pedometer encourages physical activity - but not for everyone
eHealth can improve our lifestyle without the involvement of a healthcare provider. Talia Cohen Rodrigues investigated the possibilities for people with cardiovascular diseases. ‘People with a low socioeconomic status may be more difficult to reach with eHealth.’ She will defend her doctoral thesis…
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Documentary film alumna Visual Ethnography on show at Pakhuis de Zwijger
Wilke Geurds graduated from the Visual Ethnography master's programme last year with her intimate and vulnerable documentary 'F*ck Endo. More than just menstrual pain.'.
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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Medical Delta professor Jaap Harlaar: ‘This form of collaboration is in my blood’
Hundreds of thousands of Dutch people suffer from pain caused by knee osteoarthritis and the number is rising fast. Prof. Jaap Harlaar specialises in clinical biomechanics. His research is helping improve osteoarthritis treatment. Harlaar has been appointed Medical Delta Professor and now holds posts…
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Looking at the person beyond the blood clot
How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.
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Young researchers looking for partnerships in Indonesia
A number of young researchers recently took part in a knowledge mission to Indonesia, aiming to build a lasting relationship with the country. How did they find the trip, what did they do, and how are they creating new connections with scientists in Indonesia?
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University doctor
Leiden University is committed to creating a pleasant working environment for its staff. It may nevertheless happen that you find yourself unable to work due to a temporary or long-term illness or disability. The university doctors can help you reduce health risks and give you advice regarding your…
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University doctor
Leiden University is committed to creating a pleasant working environment for its staff. It may nevertheless happen that you find yourself unable to work due to a temporary or long-term illness or disability. The university doctors can help you reduce health risks and give you advice regarding your…
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Hanneke Hulst new Scientific Director Institute of Psychology
Prof. Hanneke Hulst has been appointed Scientific Director of the Institute of Psychology by the Board of the Faculty of Social and Behavioural Sciences. She will start on 1 February 2024 for a period of 3 years, succeeding Andrea Evers and interim director Serge Rombouts.
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Research projects launched into biodiversity in food and horticulture production
Two Leiden research projects that focus on increasing the biodiversity of Dutch production systems for food and ornamental horticulture have started thanks to funding from the Dutch Research Council's KIC research programme.
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Not everyone has health goals top of mind
Preventing or delaying disease often requires lifestyle changes, which turns out to be difficult. Valentijn Visch and Sandra van Dijk are researching how to help people change their behaviour.
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Nature Communications paper on therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression
Cancer immunotherapy represents a significant breakthrough in cancer treatment. However, tumors have numerous mechanisms by which they evade destruction by the immune system. It is therefore necessary to decipher and reverse these mechanisms in order to improve immunotherapies.
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Jos Raaijmakers nominated for Huibregtsenprijs 2022
The research project of Jos Raaijmakers is nominated for the Huibregtsenprijs 2022. The researcher of NIOO, with a guest appointment at the Institute of Biology Leiden (IBL), is one of six nominees. On the Evening of Science & Society (Dutch: Avond van Wetenschap & Maatschappij), 10 October 2022, the…
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Veni grants for 21 researchers from Leiden University
An impressive 21 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).
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Researchers from Leiden visit Indonesia on knowledge mission
A delegation from Leiden University recently embarked on a knowledge mission to various NGOs, universities and government organisations in Indonesia. New partnerships were formed and important knowledge exchanged, and researchers from Leiden gave guest lectures.
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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Hanneke Hulst discusses blind spots and the importance of collaboration
Hanneke Hulst explaines how she is trying to bridge the gap between science and health care. ‘For a neuroscientist to actually contribute to solutions for patients, you have to work across disciplines.’
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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Inaugural lecture: 'Connecting disciplines advances science and care’
On Friday 9 September, Jeanin van Hooft, Professor of Gastrointestinal and Liver Diseases, will deliver her inaugural lecture titled: 'The scope of connection'. She emphasises the value of collaboration and connection for scientific research. In addition, she pleads for more diversity; according to…
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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A real professor in the classroom: ‘What do you like best about your work?’
Each year on the university’s birthday, children at primary schools in Leiden and The Hague have a lesson from a professor – about children’s rights and robots in surgery, for example. The children get to do activities. And ask questions: ‘How do you become a professor?’
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Draw on behavioural science for a healthy lifestyle
Healthy lifestyle campaigns are often unsuccessful. It is hard to get people to eat healthily or do more exercise. Behavioural science expertise should be drawn on at a much earlier stage in policy development, say twelve behavioural scientists in a position paper. They will present the paper to Maarten…
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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Subsidy for development of tools for rheumatic diagnosis
Digital diagnostic tools should improve the diagnostic process of patients with musculoskeletal complaints, so that they can receive the right treatment more quickly.
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Obesity and medication: when does bodyweight matter?
How can we best treat infectious diseases in people with obesity? Hospital pharmacist and PhD researcher Koen van Rhee studied how obesity affects blood levels of two commonly used medicines. He also developed a method for pharmaceutical companies to test new drugs on this patient group.
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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From research to practice: Leiden researchers awarded European grant
Various Leiden researchers have been awarded a European grant to explore the commercial or societal potential of previous research.
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Maternal mortality in the Netherlands halved in recent years
The number of women in the Netherlands dying before, during or after childbirth has halved.
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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eLaw publishes article in Computer Law & Security Review
In healthcare, gender and sex considerations are crucial because they affect individuals' health and disease differences. Yet, most algorithms deployed in the healthcare context lack close consideration of these aspects and do not account for bias detection. In their latest paper, Eduard Fosch-Villaronga,…