905 search results for “michel als” in the Public website
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Attentional processing of itch and pain
This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.
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COVID-crisis of COVID-kans? Adaptief en lerend bestuur in het LUMC en de regio
Covid-19 is een disruptieve ontwikkeling die hier en nu veel vraagt van zorgprofessionals, bestuurders en managers. Hoewel de crisis nog volop bezig is, is nu al duidelijk dat het Coronavirus een blijvende impact zal hebben op zorginstellingen en fundamentele vragen oproept over hoe we onze zorg optimaal…
- Book Chapters
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Research Paradigms and Instruments
Our team is involved in the translation and adaptation of several questionnaires, for research purposes. Information about each questionnaire is listed below.
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Does the human brain process angry voices automatically?
Using brain imaging to discover the area in the brain that recognizes emotion.
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Certificate Dutch as a Foreign Language
The CNaVT exam is the official, international exam of Dutch as a Foreign Language for all who learn Dutch all over the world. The Catholic University of Leuven organizes the exam. The Dutch Language Union has commissioned this collaboration.
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The role of hearing signers in the development of channel specific structures in sign languages of deaf communities
In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.
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Praktische zaken - Toelating en aanmelding
Een medewerker van Frontoffice Studentenzaken legt uit waar je vooral rekening mee moet houden als je je wilt aanmelden bij de Universiteit Leiden.
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Next generation lipopeptide antibiotics
This thesis describes the evaluation of novel natural products with antibacterial activity enabled by total chemical synthesis.
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Gaining control of lipid-based nanomedicine by understanding the nano-bio interface
Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…
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De stad en de dood
Het is een wijdverbreid idee dat (post-)middeleeuwse steden een sterfteoverschot hadden en zij slechts in leven konden blijven door de toestroom van migranten; een fenomeen dat bekend staat als het ‘urban graveyard’-effect. Over details valt te twisten, maar duidelijk is dat de stad en de dood dichter…
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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Profile 1. State formation in medieval Frisia
Politically speaking, the Frisian coastal area constitutes a special case in late medieval Europe since it was not subject to an overlord as it withstood feudalization in the 13th century. Its many sub regions, which were dominated by elites of small noblemen and freeholders, long time succeeded in…
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HZ Kenniscentrum Zeeuwse Samenleving
HZ Kenniscentrum Zeeuwse Samenleving doet op vraag van regionale overheden en maatschappelijke organisaties onderzoek naar actuele en maatschappelijke thema’s in de provincie Zeeland. De uitkomsten van onderzoeken en analyses worden gebruikt voor kennisopbouw en als basis voor beleidsopbouw en -ontwikkeling.…
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Music Cognition
Knowledge and culture subproject 1:
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Parking garage Gorlaeus Building
, Wassenaarseweg 76, 2333 AL, Leiden
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Contact
Contact information & address
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Democratie, deugden, docentschap
On 8 November, Jordi Wiersma defended the thesis 'Democratie, deugden, docentschap: de docent als gids in de democratie'. The doctoral research was supervised by Andreas Kinneging and Paul van Geest.
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Reports
Overview of the CML reports
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Jubileumcongres Belgisch-Nederlands Boekbandengenootschap
Op 22 november vindt in Nijmegen een feestelijk congres plaats ter ere van het 40-jarig bestaan van het Belgisch-Nederlands Boekbandengenootschap. Voor onderzoekers organiseren het Belgisch-Nederlands Boekbandengenootschap en de Radboud Universiteit bovendien op donderdag 21 november 2024 de workshop…
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MicroGRICE: Greenhouse Gas Reduction in RICE: MICRO-biome climate smart applications
Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?
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Toward curriculum reform: an empirical research about the implementation of national mathematics curriculum reform in China
This is a research project on the implementation of national mathematics curriculum reform in Chinese junior high school. The research is expected to provide insight into the ways and reasons of mathematics teachers in Chinese junior high school for implementing national curriculum reform.
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Small molecule inhibitors of Nicotinamide N-Methyltransferase (NNMT)
NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…
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Phenoconversion
Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…
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Epistemological Inquiry into Islam’s Moral Economic Teachings, Legal Discourse, and Islamization Process
Mr. S. Al Daghistani defended his thesis on 30 November 2017
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Die Ersten Bauern Mitteleuropas
Eine Archäobotanische untersuchung zu Umwelt und Landwirtschaft der Ältesten Bankkeramik.
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The shadow side of positive organizational change: practitioners’ experience navigating dialectical tensions in appreciative inquiry
On 23 April, Sheila Haji defended the thesis 'The shadow side of positive organizational change: practitioners’ experience navigating dialectical tensions in appreciative inquiry'. The doctoral research was supervised by Jan Adriaanse, Mark Dechesne and Renee Heath.
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e-Coach: Tailored cognitive-behavioral e-Health care for patients with chronic somatic conditions
The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.
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Publications
Disclaimer: Manuscripts related to the Resilience Center are for academic purposes only and are not intended for mass distribution or copying. Please refer to applicable laws for fair use, including copyright holders' restrictions on publications.
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Correlates of Complexity
Essays in Archaeology and Assyriology Dedicated to Diederik J.W. Meijer in Honour of his 65th Birthday
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Spectacle and Surveillance: The Making and Unmaking of Collective Visual History
What is the iconography of propaganda specifically as it relates to the historical development of political ideologies in modern Egypt and how was/is this propaganda disseminated among creative fields such as cinema, art, monuments, architecture, and literature?
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Body and Ki in GiCheon: Practices of Self-Cultivation in Contemporary Korea
Yeonhwa Jeon defended her thesis on 6 July 2017.
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From Technological Humanity to Bio-technical Existence
Explores the relationship between technics and humanity, tracing the emergence of a bio-technical conception of existence in contemporary continental philosophy. Suny Press
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“Solidarity” and “Truth” in the work of the Jewish Author and Poet Jacob Israël de Haan (1881-1924)
How De Haan is using language in general and his specific style of language in particular to provide truth, solidarity and justice for both the individual and the collective?
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Management Team and Daily Board
Daily management at the Institute of Biology Leiden is executed by the Scientific Director, the Director of Education, the Director of Operations and the Management Assistant. Research and education are managed collaboratively, with strategic input from various representatives and gremia, including…
- Lectures
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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Integrated life cycle assessment and life cycle costing of concrete recycling in the Netherlands
Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…
- Italian 1
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Trends in social assistance, minimum income benefits and income polarization in an international perspective
Social assistance and minimum income benefits are important instruments as a safeguard against low income and poverty. There have been major developments in minimum income benefits both in developed and developing countries over the last decades. Our study collects several empirical studies regarding…
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The use of self- and peer assessment with video in courses on professional practice
How can video on professional practices in university courses be used in a valid and useful way for assessment and feedback?
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A three-step approach to supporting patient self-management in clinical practice
The aim of this project is to develop, evaluate, and multicentre implement a blended form of cardiac rehabilitation that uses a theory-based approach to guide patients to full self-management.
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Of marks and meaning : a palaeographic, semiotic-cognitive, and comparative analysis of the identity marks from Deir el-Medina
Kyra van der Moezel defended her thesis on 7 September 2016.
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Leiden physicists detect single nanoparticles in motion
It's pretty hard to spot a single 5 nanometer particle. Leiden physicists pulled it off by turning a 120 nm gold rod into a detector.
- Italian 3
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Biomolecular analyses of skeletal remains in the circum-Caribbean across the historical divide (A.D. 1000-1800)
As part of the NEXUS1492 project, this project will use ancient DNA techniques to shed new light on the demographic and health history of the Caribbean and the impact of European colonization on indigenous communities in the region.
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Low-Resource Chat-based Conversational Intelligence (LESSEN)
Access to information is a human right (United Nations, 1948). Information technology, such as search engines and recommender systems, has become the key mediator and facilitator to connect people to information (White, 2016). Conversational artificial intelligence (AI) technology is increasingly being…
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Handbook on life cycle assessment
Writing an operational guide to the ISO standards for LCA and related sub-projects.
- Italian 4