The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

Research within our group revolves around the atomic structures of large bio-molecules and their complexes.

Bioactive Molecules is one of the four research themes of the Institute of Biology Leiden.

Investigating domestic crafts and subsistence activities through experiments and material analysis

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…

The explanation from physicist Scott Waitukaitis for the screaming and bouncing gel balls in a hot pan has been covered in several media, including the Washington Post.

Optimised antibiotic combinations can combat bacteria more effectively while also slowing the development of resistance. Scientists from five European countries are joining forces to identify such combinations and provide tools for others to do the same. The project is led by Professor Coen van Hasselt…

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.

A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

The Leiden Institute of Physics (LION) offers bachelor and master level education in physics at Leiden University.

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.

The quality of the care for our senior citizens could be improved. With an eye for the biological, social and management aspects, this Master’s programme provides important insights for improvements. The Master’s in Health, Ageing and Society starts you thinking, puts you to work and gives direction…

The Physics master offers you a lot of options to create your own programme. There is also the possibility to follow an internship abroad at another university or company or follow courses at another university in the Netherlands or abroad.

We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.

On an apparently normal cube a pattern of hollows and bulges appears when the cube is compressed. A method has been developed to design such three-dimensional structures and to construct these using simple building blocks. Publication in Nature.

Manufacturers produce high-end technology mostly top-down with large machinery, but small particles are able to build structures by themselves from the bottom up. A major challenge is that these particles easily clump together. Leiden physicist Daniela Kraft has developed a method to use this phenomenon…

Narrative Science examines the use of narrative in scientific research over the last two centuries.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

Promotor: G. A. van der Marel, Co-promotor: D. V. Filippov

Biological and behavioural measurements of parent-child interactions.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

How did the life course, with all its biological, social and cultural aspects, influence the lives, writings, and art of the inhabitants of early medieval England?

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

Find out about the effects of Brexit on contracts and supplies.

Research in the Jawerth lab focuses on using principles from soft condensed matter physics to understand important biological materials.

Promotor: Prof.dr. E.J.J. Groenen

Key publications of the Biomedical Microscale Analytics group.

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.

Over the past decade, several novel types of spatially resolved

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

The miniaturization of machines towards the micron and nanoscale requires the development of joint-like elements that enable and constrain motion. We developed a facile method to create colloidal joints, that is, anisotropic colloidal particles functionalized with surface mobile DNA linkers that control…

The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…

Are you interested in an interactive Master’s programme that prepares you for important roles in the innovations of our future healthcare? The Health, Ageing and Society Master’s focuses on biological, individual and social aspects of healthy ageing, as well as emphasizing on personal and professional…

Are you interested in an interactive Master’s programme that prepares you for important roles in the innovations of our future healthcare? The Health, Ageing and Society Master’s focuses on biological, individual and social aspects of healthy ageing, as well as emphasizing on personal and professional…