From nanoparticles to colliding ice planets and from biological origami to new x-ray scanner techniques: this year again, our scientists have made wonderful discoveries. From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, take a look at each institute's…

In the spirit of 'unity in diversity', our objective is to promote insight into and appreciation for the wonder that the same physical laws and mathematical concepts apply to the whole of nature, from the largest to the smallest energy and length scales. We strive for the application of abstract theoretical…

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.

Leiden University linguist Lisa Cheng speaks two Chinese languages, as well as English and Dutch. She is a strong supporter of the European Commission's wish that every European citizen learns to speak several languages. ‘Speaking three languages is not that difficult.’

Some examples of AI-research done at Leiden.

How can video on professional practices in university courses be used in a valid and useful way for assessment and feedback?

The research programme Formal Theoretical and Experimental Linguistics brings together LUCL researchers who focus mainly on formal theoretical and experimental linguistics.

Three of the four Heineken Young Scientists Awards for 2022 have gone to researchers from Leiden: chronobiologist Laura Kervezee, physicist Jordi Tura i Brugués and health psychologist Liesbeth van Vliet.

The explanation from physicist Scott Waitukaitis for the screaming and bouncing gel balls in a hot pan has been covered in several media, including the Washington Post.

Female and male songbirds sing equally elaborate songs in some species, but in others, females do not sing like males or not at all. How did such pronounced differences in male and female communication evolve?

The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.

The skin has recently gained attention within body studies for its many specific cultural and social associations, in addition to its biology. This project aims to examine the different layers of meaning and the functions invested in the skin in ancient Greece: how did ancient Greek literary and medical…

The MSc programme Physics offers 5 research-oriented specialisations where you can focus on Theoretical Physics, Quantum Matter and Optics, Biological and Soft Matter, or Cosmology. You can also combine Physics with education, management or science communication.

The research master's specialisation Clinical and Health Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.

Research within our group revolves around the atomic structures of large bio-molecules and their complexes.

This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

Bioactive Molecules is one of the four research themes of the Institute of Biology Leiden.

Investigating domestic crafts and subsistence activities through experiments and material analysis

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.

On an apparently normal cube a pattern of hollows and bulges appears when the cube is compressed. A method has been developed to design such three-dimensional structures and to construct these using simple building blocks. Publication in Nature.

Manufacturers produce high-end technology mostly top-down with large machinery, but small particles are able to build structures by themselves from the bottom up. A major challenge is that these particles easily clump together. Leiden physicist Daniela Kraft has developed a method to use this phenomenon…

The Royal Netherlands Academy of Arts and Sciences (KNAW) has appointed 26 new members. Three of them are Leiden professors: Luuk de Ligt, Lisa Cheng and Marc Koper. The new Academy professors will be installed on 8 June.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…

Following their application to system biological models, control theory techniques have further potential to aid in the understanding and application of quantitative systems pharmacology models.

We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.

The Leiden Institute of Physics (LION) offers bachelor and master level education in physics at Leiden University.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

Combining different disciplines, researchers work together to formulate innovative solutions to societal problems.

Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.

The quality of the care for our senior citizens could be improved. With an eye for the biological, social and management aspects, this Master’s programme provides important insights for improvements. The Master’s in Health, Ageing and Society starts you thinking, puts you to work and gives direction…

The Physics master offers you a lot of options to create your own programme. There is also the possibility to follow an internship abroad at another university or company or follow courses at another university in the Netherlands or abroad.

We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.