6,433 search results for “based” in the Public website
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Sustainability and Co-participation Conference
More than 30 members of Programme Committees, Faculty Councils and the University Council met online on 27 November with a mission: how can university co-participation work towards a more sustainable university in terms of education, research, and operations? The Leiden University Green Office and the…
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Energy & Sustainability
Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…
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Contribute
The editorial board of Inter-Section happily invites contributions from ambitious archaeology students, or recent graduates, of Leiden University’s Faculty of Archaeology. We welcome all sorts of article submissions, as long as they are based on the original work of the author and contribute to the…
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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The more the better? The complementarity of United Nations Institutions in the fight against torture
This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…
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Performance Requirement Prohibitions in International Investment Law
On Tuesday 17 October 2017 Alexandre Genest defended his PhD dissertation ‘Performance Requirement Prohibitions in International Investment Law’ as part of a double PhD programme at the Universities of Leiden and Ottawa. The Supervisors are Professors M.E. Koppenol-Laforce. F. Baetens (Universities…
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Unsprayed field margins: effects on environment, biodiversity and agricultural practice
A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…
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Mapping for meaning. Using concept maps to integrate clinical and basic sciences in medical education
In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?
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Post-Crimea Shift in EU-Russia Relations: From Fostering Interdependence to Managing Vulnerabilities
Ludo Block wrote the eleventh chapter of the book 'Post-Crimea Shift in EU-Russia Relations: From Fostering Interdependence to Managing Vulnerabilities'. His chapter 'Business as Usual? Police Cooperation under a Cloud of Political Animosity' can be found on page 204 of the book.
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Development of an intradermal tuberculosis vaccine by combining dissolvable microneedle arrays and Mycobacterium tuberculosis antigen-containing
Mycobacterium tuberculosis (Mtb), the pathogen causing tuberculosis (TB), is the leader among all pathogens responsible for the most human deaths today and it is considered as one of the top 10 causes of death worldwide. There is an increasing occurrence of multidrug-resistant and even totally drug-resistant…
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Research
Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.
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Governing Cyberspace: Behavior, Power and Diplomacy
Governing Cyberspace: Behavior, Power and Diplomacy is based on a selection of papers presented during The Hague Program for Cyber Norms' inaugural conference Novel Horizons: Responsible Behaviour in Cyberspace from 5-7 November 2018 in The Hague. The volume is edited by Dennis Broeders and Bibi van…
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Gold Matters
Gold Matters: Sustainability Transformations in Artisanal and Small-scale Gold Mining: A Multi-Actor and Trans-Regional Perspective.This project explores whether a transformative approach towards sustainability can arise in Artisanal and Smallscale Gold Mining (ASGM).
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Learner–learner interaction in digital learning environments: what and how are we measuring?
Galikyan’s dissertation examines how the multidimensionality of learnerlearner interaction data and the multifacetedness of learner-learner interaction itself impact the measurement of learner-learner interaction in digital learning environments.
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Design and evaluation of video portfolios: reliability, generalizability, and validity of an authentic performance assessment for teachers
The research study presented in this dissertation focuses on issues pertaining to the reliability, generalizability, and validity of authentic performance assessments of teachers.
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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Evolutionary Developmental Biology of Bitterling Fish
We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…
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Overcoming ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019)
On 1 June 2022, Bruno Braak defended his thesis entitled 'Overcoming ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019).' The doctoral research was supervised by Prof.dr. J.M. Otto, Dr.ir. C.I.M. Jacobs, and Dr. C. Leonardi…
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CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.
- Ostia Speaks
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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The Netherlands X-omics Initiative
The Netherlands X-omics Initiative is a new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.
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A Corrective Approach to Reduce Aircraft Greenhouse Gas Emissions
On Thursday 16 November 2017 Thomas Leclerc defended his PhD Dissertation ‘A Corrective Approach to Reduce Aircraft Greenhouse Gas Emissions. Contribution to the Study of Interactions between Legal Orders of International Law’. The Supervisors are Professor P. Mendes de Leon and Professor L. Grard.
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Pushing the envelope of nuclear magnetic resonance spectroscopy for paramagnetic systems
A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…
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Research
Research at the BPOC/SSNMR group is comprised of the following research themes:
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Consonant and lexical tone interaction: Evidence from two Chinese dialects
On the 4th of June, Menghui Shi successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Menghui Shi on this achievement!
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Social Forces, States and Hydropolitics of the River Nile: Case Studies of Egypt, Ethiopia, Sudan
This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.
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Legitimacy in Multistakeholder Global Governance at ICANN
This article explores levels and patterns of legitimacy beliefs with respect to multistakeholder global governance at ICANN. From a large and systematic evidence base, Jongen & Scholte have found that ICANN has strong legitimacy underpinnings among its staff and board, as well as quite uniformly moderate-to-high…
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Creating Global Scenarios of Environmental Impacts with Structural Economic Models
To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Right-Wing Extremism in the Military
This research paper seeks to examine the nature of the nexus between right-wing extremism and the military by surveying five potential consequences (i.e., problem areas) arising from the presence of right-wing extremists within the armed forces of twelve Western countries.
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.
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Play and Media
Play and Media is one of the six research themes of the LUCAS Modern and Contemporary cluster.
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Make it and Break it: the cycle of pottery
A study of the technology, form, function, and use of pottery from the settlements Uitgeest-Groot Dorregeest and Schagen-Muggenburg 1, Roman Period, North-Holland, the Netherlands
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Mediating Islam in Post-Suharto Indonesia: Performing Dakwah through Popular TV Shows
On the 9th of November Syahril Siddik successfully defended a doctoral thesis and graduated.
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Strategies for Mechanical Metamaterial Design
On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.
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Utopia: Universal Three-dimensiOnal Passport for process Individualization in Agriculture
Agricultural foods naturally vary in their detailed internal structure. To facilitate early detection of health hazards due to contamination or disease, predict maturity and minimize wastage, it is critical to take into account the internal characteristics of each individual product, as these enable…
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Islam in Central Asia: Shrines along the Silk Road
This programme examines cultural space, national identity and the politics of tangible and intangible heritage in Islamic Central Asia.
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STORMING THE GAMERGATE
How can video games be used as feminist tactical media to expose the root of exclusions (based on sex, gender, class, race, ability, etc.) pervasive to gaming communities?
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Vital Art: Transgender Portraiture as Visual Activism
In what ways can visual art play a vital role in countering the discriminating stigma experienced by transgender communities?
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About LLC
The Leiden Leadership Centre (LLC) at Leiden University is a platform for research and education in the field of public leadership, based in The Hague. We aim to advance knowledge and contribute to the development of public leadership - both in science and in practice.
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Was macht Hypertext mit Text? Textlinguistische Einsichten in das be- und entgrenzende Wirken von Paratext und Text in Hypertext
This dissertation focuses on the question how text and paratext contribute to the way that text in a network-like environment is clearly bordered and at the same time can easily be linked to other texts.
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Dutch Extract Library
We like to welcome you kindly to the Dutch Extract Library.
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Combining Participatory Mapping and Geospatial Analysis Techniques to Assess Wildfire Risk in Rural North Vietnam
Andrea Bartolucci is Assistant Professor at Institute of Security and Global Affairs. In this study, the scholars adopted a multidisciplinary approach to investigate wildfire risk in Van Chan district in northern Vietnam, a region where official data are sometimes difficult to collect or inconsisten…
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Spatiotemporal building stock modeling for residential decarbonization in the Netherlands
Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.
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RESTORING T-CELL HOMEOSTASIS BY IN VIVO MANIPULATION OF DENDRITIC CELLS
The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…
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The adoption of sound change
On the 13th of October, Cesko Voeten successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Cesko on this achievement!