1,756 search results for “synthesis he molecular” in the Public website
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Youthful DNA in old age
The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing. A study of over 3,000 people shows that this is not true for everyone: there are people whose DNA appears…
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Leiden University and LUMC join Netherlands Centre for One Health
Leiden University and Leiden University Medical Center have joined the Netherlands Centre for One Health (NCOH), further strengthening the academic network in which such problems as antimicrobial resistance are studied.
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New measuring method facilitates drug research
Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.
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Bacteria that degrade plastic: Unilever Research Prize for master’s student Jo-Anne Verschoor
Jo-Anne Verschoor wins the Unilever Research Prize 2020. The master's student in Biology developed a method to test whether bacteria are capable of degrading plastic. Verschoor: 'Using specific enzymes from these bacteria, we may be able to efficiently recycle plastic in the future.
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MRI Machine at the Nanoscale Breaks World Records
A new NMR microscope gives researchers an improved instrument to study fundamental physical processes. It also offers new possibilities for medical science, for example to better study proteins in Alzheimer patients’ brains. Publication in Physical Review Applied.
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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Different medication dosage for morbidly obese patients
PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…
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Aggressiveness of cancer cells halted
Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.
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New insight into tuberculosis infection
Michiel van der Vaart with a team from Leiden University and the LUMC, led by IBL-researcher Annemarie Meijer, discovered that DRAM1 is a protein that regulates anti-bacterial autophagy, a defense mechanism against infections such as tuberculosis.
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Macrophages as drivers of an opportunistic infection
The opportunistic bacterium Burkholderia cenocepacia is feared by cystic fibrosis patients and is emerging in hospital-acquired infections. An international study sheds new light on the infection mechanism of this opportunistic pathogen that may have large implications for treatment strategies.
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Unilever Research Prize for master student Lukas Kiefer
Leiden Biology student Lukas Kiefer has won the Unilever Research Prize 2018 for his research into efficient production of a new antibiotic. Kiefer: ‘I want to make biological medicines available to people in need.'
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Fighting diseases with good bacteria
Researchers from the Institute of Biology Leiden have discovered how good intestinal bacteria regulate our innate immune system. This surprising discovery could make it possible to treat diseases related to inflammation, such as diabetes and colitis, with a cocktail of good bacteria. Publication in…
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Cost-effective catalyst converts CO2 into natural gas
A discovery made in Leiden helps not only to make natural gas from CO2 but also to store renewable energy. Research by Professor Marc Koper and PhD student Jing Shen shows how this process can be implemented in a cost-effective and controllable way. Nature Communications, 2 september 2015.
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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NWO Open Competition grants for two research projects
Two research projects from Leiden University have been awarded funding within the NWO (Dutch Research Council) Open Competition Domain Science programme. This funding finances innovative, fundamental research of high quality within the domain of Exact and Natural Sciences.
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LIC Lecture: Photoswitchable self-assembly
Lecture
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LED3 Lecture: Organoids to model human health and disease in vitro
Lecture
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How to develop cancer drugs with less side effects
Lecture, Tuesday Talks: Science Insights
- Toward understanding the interactions between liposomes and graphene for the application of lipidic structures on graphene
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Het grenzeloze leven: de fascinerende wereld van celwandloze bacteriën
Inaugural lecture
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Van Marum Colloquium: Plasma Chemistry to aid the Energy and Materials Transition in the Process Industry
Lecture
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LIC Lecture: Structure-based development of immunoproteasome inhibitors
Lecture
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25 Years Bio-Pharmaceutical Sciences: Combined fascination
25 Years ago, the Center for Bio-Pharmaceutical Sciences was founded at Leiden University; one year later, in 1985, the education program of Bio-Pharmaceutical Sciences started. On Friday September 18th, this was celebrated with a Symposium, an anniversary booklet, and a grand party.
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NWO Vidi grant for 11 Leiden researchers
Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.
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Archaeologists in action: stories from the field
During the summer, staff and students of the Faculty of Archaeology travel to all parts of the world, initiating or joining fieldwork projects. Read some of our students' stories here!
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Veni grants for 19 young Leiden researchers
Nineteen researchers who have recently been awarded their PhD are to receive a Veni grant of up to 250,000 euros. Science funding agency NWO has awarded a total of 158 Venis in this round; Leiden University's share of the awards is 12 percent.
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Leiden expands collaboration with Mexico
A delegation from Leiden University is currently visiting Mexico to initiate collaboration with universities and science funding bodies in the country and to extend and expand existing partnerships. Rector Magnificus Carel Stolker is confident enough already to call it a success.
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Making everything we know computer-readable
Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…
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LED3 & LUCID Drug Discovery Meeting
Conference
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CANCELLED: LED3 Lecture: Covalent Drug Discovery
Lecture
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Poster sessions
Speech Prosody 2024 includes several poster sessions, the description of which you can find below.
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Somayah Elsayed
Science
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Marc Koper
Science
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Mario van der Stelt
Science
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Van Marum Colloquium - The in-situ observation for electrochemical energy experiment by Operando X-ray spectroscopy
Lecture
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A Bitter Sweet Symphony
Inaugural lecture
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LED3 Lecture: Imaging and Editing the Lipidome
Lecture
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Hall of Fame 2020
In 2020, many of our staff and students have again won prestigious prizes and been awarded important research subsidies.
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MCBIM Colloquium: Supramolecular systems based on CO2 and metal waste material: from fundamental investigations to recycling plant
Lecture
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Reedijk Symposium 2024: Exploring the Nanomachinery and Substrate Functions of Mycobacterial Type VII Secretion Systems
Lecture
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How to make green hydrogen
Lecture, Tuesday Talks: Science Insights
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Prizes for research internships in Suriname and on the Spanish Costa
They were pleased enough to receive a grant from the LUF International Study Fund (LISF). That the same research internship would also win them a prize is beyond their wildest expectations. Phebe van Langevelde and Nynke Anna van der Mark won, respectively, the Janneke Fruin-Helb grant for the best…
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Parade of creative science communication products
From bedtime stories about mathematics to podcasts about microplastics and games on weeds: master students from the Science Communication & Society track presented the real-life products they developed during their final presentations on 20 December. Many of the products are already implemented by c…
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Stacked graphene layers act as a mirror for electron beams
Stacked layers of graphene can act like a mirror for beams of electrons. Physicists Daniël Geelen and colleagues discovered this using a new type of electron microscope. In an article in Physical Review Letters, they describe their results, which could lead to the development of optics for electron…
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The hunt for selective drugs
How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…
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Faculty of Science opens academic year with live stream in homely setting
From a white leather armchair, on which Barack Obama once sat, Dean Michiel Kreutzer opened the academic year. This time not with visitors, but completely corona-proof via a live stream. In a homely setting, Kreutzer spoke with several guests, including Covid-19 researcher Thomas Hankemeier and brand…
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Tunnel vision alarm in the search for more efficient hydrogen cells
A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…
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Laura Heitman uses her expertise to fight cancer
Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.
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Is there oxygen on exoplanets? New telescope finds out
To what extent does exoplanet Proxima b resemble our Earth? And is there some form of life present? Astronomers hope to find answers to these questions with the new European Extremely Large Telescope (ELT). An NWO research grant of €18 million will allow a Dutch consortium to continue building instruments…