Unfolding potential

Ideology and Christianity in Japan shows the major role played by Christian-related discourse in the formation of early-modern and modern Japanese political ideology.

This dissertation reports on the pedagogical content knowledge (PCK) of science teachers during a professional development program. This research intended to help us understand why and how teachers make their classroom decisions as they teach science.

In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, discusses the emergence and diffusion of ‘global health’ as a concept. In addition to bringing a fresh perspective on the origins of global health, the paper contributes to the globalization debates by…

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

Summary

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: Prof. dr. B. de Smit

Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…

In the near future oral polio vaccine (OPV) will be replaced by inactivated polio vaccine (IPV) as part of the eradication program of polio. For that reason, there is a need for substantial amount of safe and more affordable IPV for low-income countries. Bioneedles, which are biodegradable mini-implants,…

The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

Light obscuration (LO) is the current standard technique for subvisible particle analysis in the quality control of parenterally administered drugs, including therapeutic proteins.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

If you can't make it to Leiden University to visit us, don't worry. Our virtual tours take you around the cities of Leiden and The Hague, show you around on campus and into our classrooms.

If you can't make it to Leiden University to visit us, don't worry. Our virtual tours take you around the cities of Leiden and The Hague, show you around on campus and into our classrooms.

The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…

How Perceived (In)Visible Dissimilarity Relates to Feelings of Inclusion at Work

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

The aim of this research was to develop an effective, generative, and practical approach to enhance students’ structure-property reasoning (SPR).

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

On the 20th of June, Camil Staps successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Camil on this achievement!

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Promotor: Prof.dr. J. den Hertog

On 12 November 2019, Larissa Koupriuchina defended her thesis 'Judgmental Adjustments in Revenue Management'. The doctoral research was supervised by Prof. J.I. Van der Rest.

Nature, nurture and neural mechanisms of social emotion regulation in childhood

Modern receptions of Graeco-Roman Antiquity are important ideological markers of the ways we envisage our own twenty-first-century societies. An urgent topic of study is: what kinds of narratives – sometimes controversial – about Antiquity do people create for themselves at this moment in time, and…

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Promotor: P.M. Brakefield

Efficiently responding to others’ emotions has great survival value, especially for social species, such as primates, who establish close, long-term bonds with group members. The closest living relatives to humans are the chimpanzee and the bonobo. Studying these species, and comparing them on the exact…

How do we get to the strategic plan? The infographic below shows the path we are taking in the coming period.

The STRINGS project is mapping development pathways for science, technology and innovation that best address the UN Sustainable Development Goals. A consortium of seven universities led by Tommaso Ciarli at SPRU at the University of Sussex and the UNDP (United Nations Development Programme) have worked…

Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…

This article discusses the coevolution of several species of the tribe Phyllantheae and moths of the genus Epicephala.

Understanding others’ emotional behavior is essential for navigating daily social life. But how is such an understanding achieved? The eye-tracking study by Yung-Ting Tsou and colleagues shows that children with hearing loss adopt a unique visual strategy that makes uses of explicit visual information…

On the 27th of February, Marta Morgado successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Marta on this achievement!

Subproject of

Does an Emotional Working Memory Training show a beneficial transfer effect on emotion regulation (reappraisal) capacities in patients with Borderline Personality Disorder?

To help us shape the future and achieve our vision and ambitions at Leiden University, we need everyone at the university to show leadership.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…