304 search results for “plaats effect” in the Public website
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The new settlement for the UK within the EU and its effects on the debate on migration in Switzerland
In February 2014, the Swiss voting population accepted a constitutional initiative that aims at limiting migration through quota and, in the field of employment, national preference.
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Vocational identity among at-risk adolescents. Effectiveness of programs at lower VET aiming at continuing education or work
The overall aim of the project is to investigate effective ways to strengthen vocational identity of at-risk adolescents in order to contribute to a successful transition from late secondary to post secondary lower vocational education or to work.
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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A cross-linguistic investigation of the onset effect in reading aloud: No need to mope about the MOPE
The global population speaks approximately 7,000 different languages and approximately half of the world’s population is bilingual. The unique orthographic characteristics of different languages can help us to gain insight into the seemingly simple process of transforming written to spoken words (i.e.,…
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Stress Lessons in secondary education: The effectiveness and evaluation of a school-based psychoeducation program about stress
Does a universal psychoeducational course about stress in adolescents: I) lead to an increase in knowledge of stress?, II) affect the frequency with which stressors are experienced and the overall stress level?, III) create interest in a tier 2 level follow-up training?, and IV) appeal to students in…
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Development of an effective, safe, and painless intradermal tuberculosis vaccine based on microneedles loaded with antigen-containing nanoparticles
Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…
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The SMILE study: Sleep Mood lntervention: Live Effectively a group intervention in students with sleep problems
Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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Inaugural lecture: Data science and Ebola
Today, everybody and everything produces data. People produce large amounts of data in social networks and in commercial transactions. Medical, corporate, and government databases continue to grow. Sensors continue to get cheaper and are increasingly connected, creating an Internet of Things, and generating…
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Data Science & Artificial Intelligence
De minor Data Science & Artificial Intelligence geeft een toegankelijke introductie tot de theorie en praktijk van datawetenschap en kunstmatige intelligentie. Studenten leren de basis van data-analyse en patroonherkenning in grote gegevensverzamelingen, hoe computers leren en ook het interpreteren…
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The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes
The stratum corneum (SC) plays a fundamental role in the barrier function of the skin. The SC consists of corneocytes embedded in a lipid matrix.
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Michiel van Elk
Faculteit der Sociale Wetenschappen
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Effects of interdependency between teachers in professional learning communities on differentiated teaching based on cognitive differences of
What relationships exist between different types of PLCs and cognitive differentiated teaching?
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The individual level effect of symbolic representation: An experimental study on teacher-student gender congruence and students’ perceived abilities
Studies on representative bureaucracy have often confirmed the positive performance effects of bureaucracies mirroring the demographic characteristics of their clientele. However, little is known about the underlying individual level mechanisms leading to these outcomes.
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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APELAFICO: Acoustic ecology of PELAgic FIsh COmmunities: A study into the effects of construction and operation of wind farms
Do offshore windfarms affect the local biodiversity of the pelagic fish community and are fish deterred or attracted by sounds?
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Rebel with a cause: The effects of leadership encouragement and psychological safety on professionals' prosocial rulebreaking behaviour
This article examines leadership encouragement and psychological safety as antecedents of prosocial rule-breaking (PSRB) behaviour.
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Freezing conditions in warm disks: snowlines and their effect on the chemical structure of planet-forming disks
This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.
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Development of a consistent methodology for assessment of the combined effects of metal-based chemicals to lettuce (Lactuca sativa L.)
How to improve the method in quantifying the combined effects of metal-based chemicals?
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Research
At Leiden University, researchers from all disciplines work together to find answers and design innovations in the field of artificial intelligence.
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Kim de Jong
Faculteit der Sociale Wetenschappen
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Gert-Jan Lelieveld
Faculteit der Sociale Wetenschappen
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Pressure: Optical side-band cooling of a trampoline resonator and the effect of superconductivity on the Casimir force
This thesis consists of two subjects, that are both a consequence of radiation pressure.
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Terrorism Experts’ Predictions Regarding the Effects of the COVID-19 Pandemic on the Activities of Violent Non-State Actors
In this article, Yannick Veilleux-Lepage and Tommy van Steen, assistant professors at the Institute of Security and Global Affairs, discuss the degree of consensus within the field of terrorism studies regarding the impact of the COVID-19 pandemic on the activities of violent non-state actors.
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Erik van Geest
Science
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Thunderstorm: A small cultural history (1752-1830) (in Dutch)
More on the Dutch webpage.
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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HEPGAME
HEPGAME is a research project that combines the world’s fastest computer algebra system for High Energy Physics equations, FORM, with insights from artificial intelligence. The name combines High Energy Physics and Games.
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Elementaire deeltjes. Kunstgeschiedenis
Een nieuw boek in de reeks Elementaire deeltjes
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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Profile 5. The Military Orders in the Netherlands up to 1600
Fighting for the faith, caring for the sick, and praying for the soul of their benefactors were the main tasks of the military orders, who since the time of the crusades were well represented in the Netherlands in the Middle Ages, including the Frisian lands. Especially the Hospitallers and the Teutonic…
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De eerste mensen in de Lage Landen
Nederland ligt in de periferie van het verhaal van menswording. De evolutie van onze familie vindt lang exclusief in Afrika plaats. En, als Europa eenmaal bewoond wordt door mensachtigen, ligt het zwaartepunt ten zuiden van onze streken. Toch heeft ons land een aantal interessante vindplaatsen en vondsten…
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Registering with a doctor
We highly advise you to register with a doctor (GP) in Leiden or The Hague before arrival or soon after you get here.
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Elastic Leidenfrost Effect enables soft engines
Water droplets float in a hot pan because of the so-called Leidenfrost effect. Now physicists have discovered a variation: the Elastic Leidenfrost effect. It explains why hydrogel balls jump around on a hot plate making high pitched sounds. Publication in Nature Physics on July 24.
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Solution to distortion effect STM scanning
STM scanning experiments on poorly conducting materials are challenging, and can cause a distortion effect. A new model corrects for this effect, allowing physicists to better study materials in their quest to understand unconventional superconductivity. Publication in Physical Review B as Editor’s…
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Using the placebo effect for your health
Even if you have a healthy lifestyle, there's a lot to experience and learn during the Healthy University Week, from 26 to 30 October. Health psychologist Andrea Evers is enthusiastic about the week ahead. She tells us about the programme and gives us a taste of her own talk on what the placebo effect…
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‘Music has so many positive effects’
This year, Leiden University celebrates its 444th birthday – and when you’re giving a party, you need great music! Neuropsychologist Rebecca Schaefer agrees. She has been fascinated by music since she was a child, and now she studies how music can make us happy, give us energy or calm us down.
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Europese productnormen en privaatrechtelijke normstelling
On 10 June 2020, Gitta Veldt defended her thesis 'Europese productnormen en privaatrechtelijke normstelling'. The doctoral research was supervised by Prof. H.J. Snijders.
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Making Sense of Illustrated Handwritten Archives
Many handwritten and illustrated archives contain a wealth of information, but are largely underexplored because they are complex and difficult for computers to decipher. The aim of this project is to develop a digital environment that resolves this challenge and connects heterogeneous archival content…
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China, een gids voor de 21e eeuw
China wordt steeds assertiever in zijn relaties met andere landen, maar achter dit beeld gaat een opmerkelijk diverse maatschappij en politieke realiteit schuil die tal van aanknopingspunten biedt voor samenwerking en verdere integratie van China in de wereld. In China een gids voor de 21e eeuw past…
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More effective data-driven policymaking
More collaboration, combining data and asking the right questions. These are a few of the recommendations that policymakers and researchers formulated at the conference 'Data gedreven Beleidsontwikkeling' on 28 November 2017.
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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The placebo effect: first world congress in Leiden
Medicines can work even if they have no active ingredient. The first international scientific conference on placebos will take place in Leiden from 2 to 4 April. Placebo researcher Andrea Evers, who is also chairing the conference, answers some pressing questions.
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The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…
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Controlling anxiety in late life (CALL)
Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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The Effects of Legal Measures to Empower Supervisory Directors
In their article; The Effects of Legal Measures to Empower Supervisory Directors: Evidence from a Financial Distress Perspective, Santen and De Bos discuss the relationship between the corporate governance structure of a company and its financial performance. Until now studies predominantly hypothesize…
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Elastic Leidenfrost Effect on cover of Nature Physics
First author Scott Waitukaitis and principal investigator Martin van Hecke have made the cover of Nature Physics with their publication on a newly discovered effect. The Elastic Leidenfrost effect explains why hydrogel balls jump around on a hot plate making high pitched sounds.
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mRNA boosters are the most effective upon receiving Janssen vaccination
A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…