With defending his thesis ‘Applications of topology to Weyl semimetals and quantum computing’, the Leiden theoretical physicist Tom O'Brien has gained the rare 'cum laude' qualification. The freshly minted PhD has started a five year research programme on quantum algorithms for quantum chemistry, funded…

Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.

An international team of laboratory astrophysicists and astrochemical modellers has shown that glycine, the simplest amino acid and an important building block of life, can form under the harsh conditions that govern chemistry in space. The results have been published this week in Nature Astronomy and…

Dementia is widely considered a progressive condition associated with changes in cognitive capacities, which promotes the idea that people with dementia need to anticipate end-of-life care preferences. There is a growing body of interventions meant to support advance care planning (ACP) for people with…

The research described in this thesis focused on the preparation of S/N functionalized carbene ligands and their transition metal complexes, and the exploration of their application as electrocatalysts for proton reduction.

On Friday 12 November Professor of Palliative Medicine Yvette van der Linden will give her inaugural lecture entitled: ‘Timeless’. How do we spend our time if illness cuts it short? According to Van der Linden much stands to be gained in the area of care during this last phase of life. Among other things,…

The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Shell cooperates with theoretical physicists and chemists of Leiden University to research how quantum computer algorithms can help simulate complex molecules.

Since February 1st, 2017 Célia Fonseca Guerra is appointed as professor at the LIC with a chair in applied theoretical chemistry. She will be a member of the Theoretical Chemistry group. Her research interests are related to bioinorganic chemistry and catalysis and her appointment at the LIC will strengthen…

Is the current existing legal framework on compulsory and voluntary care - for vulnerable young adults (between the ages of 18 to 23) - in need of revision? And if so, what kind of amendments would be advisable?

Nathaniel Martin has been appointed professor in the field of Bioorganic Chemistry within the Faculty of Science at the Institute of Biology Leiden, starting from 1 March 2018. His research focuses on using new (bio)chemical approaches to combat infectious disease, as well as on developing new molecular…

Policy plans state that children should be placed in secure youth care less often and for shorter periods. But this is problematic in practice.

Professor Hermen Overkleeft has received the esteemed Roy L. Whistler International Award in Carbohydrate Chemistry for 2024 by the International Carbohydrate Organization. The award recognises Overkleeft’s outstanding contributions to the field of carbohydrate chemistry and biochemistry.

Our educational team has been awarded an ICTO-grant of €12000 for the LACDR for flipping the Biochemistry 2 classroom.

Acute care agencies in the Netherlands are overwhelmed and this causes major problems. Physician-researcher Naomi Minderhout therefore spent the past few years at the Health Campus in The Hague researching how acute care in the Netherlands can be improved at all levels so that it remains accessible…

Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the

How do classroom demonstration experiments help students learn chemical reasoning? Marie-Jetta den Otter, PhD student at ICLON, researched this. She defends her thesis on 6 December.

As of July 1, Professor of Bio-organic Synthesis Hermen Overkleeft will be appointed as the Scientific Director of the Leiden Institute of Chemistry (LIC). He will succeed Jaap Brouwer, who has been managing the institute for the past twelve years. Overkleeft has been appointed for a period of four…

With Sylvestre Bonnet, Jeroen Codée and Remus Dame, the Leiden Institute of Chemistry (LIC) will be getting no less than three new professors. Bonnet will become professor in Bioinorganic Chemistry, Codée professor in Organic Chemistry and Dame professor in Molecular and Cellular Biochemistry.

Many parents whose children have been placed in care do not understand the basis on which the decision was taken. Dutch youth protection organisations and the Child Protection Council must better document why they request such a measure from the Juvenile Court.

During the 20th anniversary meeting of the Netherlands' Catalysis and Chemistry Conference, Marc Koper received the Netherlands Catalysis and Chemistry Award. ‘The ultimate candidate for the prize’, it says in one of the recommendation letters.

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

The Chemistry and LST master’s programmes are both structured on an individual basis and well-embedded in the research at the faculty. Those are the main conclusions of the oral report at the end of the visit of the visitation panel on October 10th.

Leiden chemist Roxanne Kieltyka is part of the 2018 Talented 12 list of the American Chemical Society. That was announced by the journal Chemical & Engineering News on 19 August.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Promotor: Prof.dr. E. Bouwman

How many children are waiting for help from youth services in the Netherlands at any given time? And exactly how long do they have to wait?

With the necessary measures, researchers restart their work in various laboratories. The Leiden Cell Observatory is one of the places where scientists resume their lab work.

A common assumption in chemistry is that the coordination number of a catalyst's surface determines the reactivity of the reaction it catalyses. Strikingly, Leiden chemists have now proven that this is not true for nature’s most simple chemical reaction: the dissociation of hydrogen. The researchers…

In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.

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Last year, chemists Dennis Wander and Hermen Overkleeft contributed to an important discovery about a widely used cancer drug. Their research has now been recognised as Finalist for the PNAS Cozzarelli Prize in the Biomedical Sciences class.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Supramolecular polymers are class of materials that are formed by non-covalent interactions such as hydrogen bonding, π-π interactions, electrostatic interactions and the hydrophobic effect.

The waiting lists in youth care are alarmingly long. This has been confirmed again by a study carried out by a Dutch foundation The Forgotten Child.

It is not possible for juvenile courts to properly assess whether it is necessary to place a child in care. This is evident from a fact sheet that has been prepared by legal scholars from Leiden University, commissioned by the Dutch House of Representatives and others.

A significant percentage of children who have spent a period in youth care institutions or foster homes since 1945 received inadequate protection from physical, psychological and sexual violence. Interventions by supervisory authorities in cases involving violence were inadequate.