368 search results for “breast centre” in the Public website
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Knowledge centre Anxiety & Stress in Youth
Our mission is to recognise and treat stress and anxiety in children as early as possible, by connecting scientific research, clinical practice and education.
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How oxygen deprivation causes cancer cells to spread
In breast cancer, metastasis rather than the primary tumour is the cause of death. A lack of oxygen in the tumour cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. PhD candidate Qiuyu Liu investigated these alterations to get more knowledge about the actionable…
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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LUCIS - Centre for the Study of Islam and Society
LUCIS promotes high-quality research on Islam and Muslim societies and actively communicates the insights and findings of that research to the larger public.
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Supporting women with breast cancer in making an informed decision about immediate breast reconstruction
PhD defence
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Accelerated Partial Breast Irradiation in elderly patients with early-stage breast cancer
PhD defence
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The path to individualised breast cancer screening
PhD defence
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Dissecting the immune microenvironment of breast cancer
PhD defence
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Mickler, Parliamentary Committees in a Party-Centred Context
Beyond the immediately visible plenum, parliaments are highly complex institutions. They work through various venues in which decisions are prepared or even taken. The two main institutions in this regard are parliamentary party groups, which comprise legislators who are elected under the same party…
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Genetic and lifestyle factors in breast cancer prognostication
PhD defence
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XIV Annual Convention of the Austrian and Central European Centres in Leiden
Impressions by Wouter Baas and Caroline Schep
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Prediction of contralateral breast cancer - Statistical aspects and performance assessment
PhD defence
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X Anniversary Convention of the Centre of Austrian Studies in November 2016 in Jerusalem
Impressions by Martin Küster, Master of Arts.
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Cancer and heredity
Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.
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Grotius Centre contributes to ICC ASP Expert Discussion on Effectiveness and Efficiency
On 24 November 2015, Prof. Carsten Stahn participated as external expert in a special plenary session of the Assembly of States Parties on the efficiency and effectiveness of Court proceedings, chaired by the co-chairs of the Study Group on Governance of the Assembly.
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Transversal Democracy Projection in the Mediterranean: A De-centred Practice Analysis
This book expands on the existing literature on the international dimension of democratization by introducing the concept of democracy projection. Democracy projection is defined as the projection of (democratic) norms through the every-day practice of interactions-beyond any donor-recipient relationship-between…
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Unravelling cancer drug resistance mechanisms
Mechanisms fro drug resistance
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Evaluation of synergistic effects of Chinese herbal medicine and natural compounds on cancers
What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?
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Refining individualized treatment in older patients with breast cancer
PhD defence
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Breaking barriers: unraveling response mechanisms to immunotherapy in breast cancer
PhD defence
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Predicting outcomes of breast cancer treatment in older patients
PhD defence
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Science for Society
By carrying out fundamental research and providing excellent education, universities become a breeding ground for innovation and entrepreneurship.
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Discovery of metastasis promoting candidate drug targets
Discovery of metastasis promoting candidate drug targets
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Ariane BriegelScience
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Peter BouwmanScience
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Cancer Drug Target Discovery
We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.
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Regulation of signal transduction pathways by hypoxia in breast cancer subtypes
PhD defence
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Calendar Academic Language Centre
Important dates in the Academic Language Centre calendar
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Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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Dual PhD Centre
December marks the 15th anniversary of the Dual PhD Centre (DPC). Director Johannes Tromp and associate professor Mark Dechesne look back and ahead. Dechesne: ‘The DPC forms a 'community of knowledge' in which science and society are connected.’
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Research
An overview of the research at the Biologics Formulation group
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BRCA1-associated breast cancer: finding new weapons for an old villain
PhD defence
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
PhD defence
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Immunosuppression in breast cancer: a closer look at regulatory T cells
PhD defence
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Attitude Switch: unraveling breast cancer cell-intrinsic mechanisms that manipulate the immune system
PhD defence
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Unraveling Multifaceted Roles of Grainyhead-like Transcription Factor- 2 in Breast Cancer
PhD defence
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A community effort to assess and improve drug sensitivity prediction algorithms
Source: Nature Biotechnology, Volume 2014, Issue June (2014)
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It began with William of Orange
Leiden University was founded in 1575, thanks to William of Orange. According to tradition, he founded the University to reward the citizens of Leiden for their resistance to the Spanish occupiers.
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Computational modeling of cellular dynamics in tumor cell migration
Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.
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Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
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4D Picture project
Helping cancer patients with treatment choices.
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Sports Centre celebrates 50 years
Online competitions, online sports, dietary advice for staff and students and 'What do they eat for lunch?' The first 'volunteer' is Vice-Rector Hester Bijl. What does her lunch usually consist of? The University Sports Centre is celebrating its fifty-year anniversary with a whole - corona-proof - programme…
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Leiden Leadership Centre Summer Café
Last Friday, June 3rd, students, professionals and academics put their knowledge to the test during the Leiden Leadership Pubquiz/Leiden Leadership Summer Café. The pubquiz, hosted by Eduard Schmidt, touched upon public leadership in the news, posed statements about remarkable leadership research, and…
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and properties of dark matter using the stellar kinematics in the centres of ultra-faint dwarf galaxies
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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2011 Leiden Centre for Global Heritage
A Centre for Global Heritage will be set up at Leiden University, that integrates the unique global breadth and quality of academic expertise at the University and the Leiden Museums with the global infrastructure of practical consultancy expertise built up over the past years by the Centre for International…
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Topic: The placebo and nocebo effects of communication
We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…
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New strategy LDE Centre for BOLD Cities
The Leiden-Delft-Erasmus Centre for BOLD Cities uses multidisciplinary big data research to help find solutions for urban problems. ‘BOLD’ stands for ‘Big, Open and Linked Data’. Data science is one of the Centre’s main disciplines.