617 search results for “anti-cancer die some” in the Public website
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Supramolecular Recognition of DNA and RNA Junction Structures for Anti-viral and Anti-cancer Therapy
Lecture
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Mathematics-based strategies for repairing tumour blood vessels
How does the extracellular matrix coordinate endothelial cell behavior during angiogenesis, and how do metabolic waste-products and matrix-degrading enzymes produced by the tumour modify the extracellular matrix so as the change the cellular coordination?
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Research
Research at the MCBIM group is comprised of the following research themes:
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Bioactive Molecules in Plant Sciences
Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.
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Microbial Sciences
In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.
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Opgezogen, opgespoten en opgeraapt: Vuurstenen en hardstenen artefacten van de Zandmotor en hun sedimentaire context
Voor zowel archeologen, paleontologen en geologen als vrijwilligers in de archeologie en paleontologie is het geen verrassing meer dat op de stranden van de Nederlandse kust fraaie vondsten gedaan kunnen worden. Vele artikelen, boeken, tentoonstellingen, congressen, lezingen, ‘zoekdagen’, krantenberichten,…
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When not all are created equal: Financial markets and some vexing public international law issues
Rutsel Martha, former Minister of Justice of the Dutch Antilles, former General Counsel of Interpol and alumnus of Universiteit Leiden, elaborated on the position of states and intergovernmental organizations (IGOs) in international financial law.
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Goedereede-Oude Oostdijk
Jasper de Bruin, Guus Besuijen, Hans Siemons & Jeroen van Zoolingen (2012). De romeinse nederzetting bij het tegenwoordige Goedereede heeft waarschijnlijk een belangrijke functie gehad in de overslag en distributie van diverse goederen, waaronder keramiek en voedingsgewassen. De opgraving van deze nederzetting…
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Knowledge of DNA repair in the fight against tumour cells
What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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APL 9 - Collection of Papers
Analecta Praehistorica Leidensia is the annual journal of the Faculty of Archaeology (formerly the Institute of Prehistory), Leiden University.
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Mathematical modeling of cellular stress pathways for mechanistic understanding of chemical-induced liver injury
Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…
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The role of AGC3 kinases and calmodulins in plant growth responses to abiotic signals
Promotor: Prof.dr. P. Hooykaas, Co-promotor: Dr. R. Offringa
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Order isomorphisms, order antimorphisms and their interplay with Jordan algebra structures
In dit onderzoek worden orde isomorfismen en orde antimorfisme bestudeerd in het algemene kader van partieel geordende vector ruimten.
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Join the anniversary day of Public Administration
Conference
- About this minor
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
How can cell wall engineering approaches be used to improve streptomycetes for industry to make new antibiotics?
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Bachelor Q&A
Op deze pagina vind je antwoorden op veelgestelde vragen.
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The Poetics of Patronage. Poetry as Self-Advancement in Giannantonio Campano (Turnhout: Brepols, 2013)
This study examines the system and poetics of literary patronage in the Renaissance by presenting a comprehensive analysis of the poetry of Giannantonio Campano. In this way, it addresses two themes largely overlooked by modern scholarship.
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Is Michael Meijer the Smartest Chemist of the Netherlands?
He is occupied with the home stretch of his promotion. But in between, there is another challenge: Michael Meijer is going through to the finals of ‘The Smartest Chemist of the Netherlands’. On Tuesday 9 October, he and five others fight for this title during the Evening of Chemistry. ‘I was dragged…
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Hermeneutics and the Humanities
Hermeneutics and the Humanities: Dialogues with Hans-Georg Gadamer / Hermeneutik und die Geisteswissenschaften: Im Dialog mit Hans-Georg Gadamer
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25 Years of Lethal Violence
How many men and women die per year at the hands of others? What are the motives behind these killings? Are there as many homicides today as years ago? How can we explain the rise and fall of homicides over time? And: What is the influence of (early) childhood and adolescence on the likelihood to commit…
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Exclusion and Renewal. Identity and Jewishness in Franz Kafka's 'The Metamorphosis' and David Vogels's 'Married Life'
In this study I explore literary structures of identity-formation in the works of assimilated/acculturated Jewish writers: Kafka’s novella “The Metamorphosis” (“Die Verwandlung”, 1912) and David Vogel’s Hebrew novel Married Life. 1929).
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About us
The Master Honours Classes & Challenges are part of Leiden’s honours education for master’s students. While the Honours Academy is responsible for the practical organisation, the education is coordinated by teachers of all faculties.
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Gaining control of lipid-based nanomedicine by understanding the nano-bio interface
Dit proefschrift beschrijft een collectie aan alternatieve strategieën voor het begrijpen, ontwerpen en toepassen van lipide nanosystemen, waarin de rol van de bio-nano interacties centraal staan. In het bijzonder wordt gekeken naar de interactie van RNA-lipide nanosystemen, bekend van de toepassing…
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Vokales Instrumentalspiel in der zweiten Hälfte des 18. Jahrhunderts.
Die Aufführungspraxis italienischer Instrumentalmusik in der Auseinandersetzung mit Vokalmusik und Text: Quellen und moderne Umsetzung
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HZ Kenniscentrum Zeeuwse Samenleving
HZ Kenniscentrum Zeeuwse Samenleving doet op vraag van regionale overheden en maatschappelijke organisaties onderzoek naar actuele en maatschappelijke thema’s in de provincie Zeeland. De uitkomsten van onderzoeken en analyses worden gebruikt voor kennisopbouw en als basis voor beleidsopbouw en -ontwikkeling.…
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Elementaire deeltjes. Kunstgeschiedenis
Een nieuw boek in de reeks Elementaire deeltjes
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Meta-ethiek. Methode, theorieën, ontwikkelingen
Do objectively correct solutions to ethical dilemmas exist? Or is ethics always a matter of your opinion against my opinion? How do you know what to do? What kind of thing is ethics anyway? Can you be an expert in ethics?
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Profile 1. State formation in medieval Frisia
Politically speaking, the Frisian coastal area constitutes a special case in late medieval Europe since it was not subject to an overlord as it withstood feudalization in the 13th century. Its many sub regions, which were dominated by elites of small noblemen and freeholders, long time succeeded in…
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Sources of Meaning among organized non-religious ‘secular’ persons
Recently, studies have shown the similarities and differences in sources of meaning between religionists, ‘nones’ and atheists (see several studies of Schnell and others). The present study that will be conducted in three European countries tries to clarify the relationship between meaning giving and…
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Political Ideas of B.G. Tilak
On 12 April 2022 Alok Oak successfully defended a doctoral thesis and graduated.
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Nog meer wereldgeschiedenis van Nederland
De Nederlandse geschiedenis is nauw verbonden met die van de wereld als geheel. Door migratie, handel en kennisuitwisseling beïnvloedden mensen elkaar over grotere afstanden en intensiever dan we lang dachten. Wereldgeschiedenis van Nederland toonde in meer dan honderd verhalen hoe internationaal de…
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Rooswijk 1740
Een scheepswrak, zijn bemanning en het leven in de 18de eeuw
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Effecten van korte gevangenisstraffen en de prijs die we ervoor betalen
Lecture
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Science & Cinema
In films kunnen de meest wonderlijke acties plaatsvinden. Maar zijn die acties in de 'echte' wereld ook mogelijk? En in hoeverre houden filmmakers ons voor de gek? Tijdens het Leiden International Film Festival komen film en wetenschap samen.
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The Manichaeans of Kellis: Religion, Community, and Everyday Life
Mattias Brand defended his thesis on 10 April 2019
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Kennemerland in metaalvondsten
Duizenden metaalvondsten die door detectorzoeker wijlen Herman Zomerdijk zijn gedaan in de regio Kennemerland schetsen een uniek beeld van Noord-Holland door de eeuwen heen. Hij zocht en verzamelde decennialang historische metalen objecten in Noord-Holland en bouwde zo een unieke metaalcollectie op.
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Small molecule inhibitors of Nicotinamide N-Methyltransferase (NNMT)
NNMT wordt beschouwd als een nieuw potentieel farmacologisch doelwit in de behandeling van een verscheidenheid van kankers, stofwisselingsziekten en andere pathologieën. Het toenemend aantal publicaties waarin de rol van NNMT bij ziekten wordt opgehelderd, heeft op zijn beurt de ontwikkeling van krachtige…
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Nietzche's Rejection of Stoicism; A reinterpretation of Amor fati
Nietzsche's famous notion 'amor fati' is often associated with the Stoic maxim to 'live in accordance with nature'; we have to fully accept our fates in order to attain happiness. But is happiness really what Nietzsche's 'amor fati' is about? And how to account for all the fiercely critical remarks…
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Cancer Drug Target Discovery
In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…
- Van Onzichtbaar naar Zichtbaar / From Invisible to Visible
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Historicizing Security. Enemies of the State, 1813 until present
The research project ‘The History of National Security, 1945-present', is funded by the Netherlands Organisation for Scientific Research (NWO), the Campus The Hague/Leiden University and the Netherlands Institute for Military History (NIMH). The project will run until the summer of 2013, when we hope…
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Laura Heitman uses her expertise to fight cancer
Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.
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"Enfin, die werkt zal eten, en daarom maar vol ijver door" Brouwers Fabriek van Aarden Vaatwerk 1901-1905
PhD defence
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The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…