1,635 search results for “beadle” in the Public website
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A closer look at stimulation thresholds and spread of excitation in cochlear implants, recording aspects and clinical implications
PhD defence
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Selective fetal growth restriction in identical twins: from womb to adolescence
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Polymer‐ and Hybrid‐Based Biomaterials for delivering biotherapeutic molecules in bone and cartilage tissue
Prof. B.P.F. Lelieveldt Summary Diseases and injuries related to bone and cartilage severely affect the function of the musculoskeletal system. They affect the life quality of patients and make them unable to move. The peculiarities of bone and cartilage structures mean that the therapeutic and…
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An Algebra for Interaction of Cyber-Physical Components
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Inhibitors and activity-based probes for retaining β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
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Advanced MRI in aortic pathology and systemic interactions
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Palladium-catalyzed carbonylative synthesis of carboxylic acid anhydrides from alkenes
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Developmental effects of polystyrene nanoparticles in the chicken embryo
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Similar but not the same - methods and applications of quantitative MRI to study muscular dystrophies
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Extinguishing metaflammation
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Evidence-based treatment of central serous chorioretinopathy
Prof. C.J.F. Boon Prof. G.P.M. Luyten Summary: Dit promotieonderzoek gaat over de oogziekte centrale sereuze chorioretinopathie (serosa). Bij deze aandoening is er sprake van ophoping van vocht onder het netvlies, wat kan leiden tot een vermindering in zicht, verschil in contrastzien en soms ook vervormingen…
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Quantitative Pharmacology Approaches to Inform Treatment Strategies Against Tuberculosis
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Indistinguishable Likeness
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Women, Family, and Litigation in Nineteenth-Century Chongqing
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Safety of the Artisan iris-fixated phakic intraocular lens
Prof. G.P.M. Luyten Summary Er zijn verschillende opties om oogsterkte (refractie) afwijkingen te corrigeren. De meest bekende opties zijn een bril en contactlenzen. Sommige mensen kunnen, of willen, geen bril of contactlenzen dragen. Er bestaan ook chirurgische opties om refractieafwijkingen te corrigeren.…
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Online Radicalisation: The Use of the Internet by Islamic State Terrorists in the US (2012-2018)
Prof. E. Bakker Prof. S. Macdonald (Swansea University) Summary Online radicalisation has been highlighted by policymakers, the media, and academics as a top security priority in recent years. This thesis unpacks the concept by empirically analysing 201 Islamic State terrorist actors in the US, discerning…
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Targeting Inter-Organ Cross-Talk in Cardiometabolic Diseases
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Breaking Barriers, Personalizing Pathways - Psychological health and self-management of people with chronic kidney disease
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Evolution and development of orchid flowers and fruits
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Raising the bar for classification and outcome assessment for clinical studies in axial spondyloarthritis
Prof. D.M.F.M. van der Heijde Summary Dit proefschrift beschrijft verschillende onderzoeken naar axiale spondyloartritis, een chronische reumatische ziekte veroorzaakt door chronische ontsteking in de wervelkolom. De belangrijkste symptomen zijn chronische rugpijn (aanwezig voor ten minste 3 maanden)…
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Generalization of placebo and nocebo effects on somatosensory sensations
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Evolutionary adaptability of β-lactamase
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Multimodality imaging in patients with valvular heart disease and systemic diseases
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Kearifan Kesehatan Lokal
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Consumed by a forbidden emotion
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The Assembled Palace of Samosata
Prof. M.J. Versluys Prof. M. Blömer (Universität Münster) Summary: Dit proefschrift vormt de eerste volledige archeologische publicatie van de opgravingsresultaten van het zogenaamde ‘paleis van Samosata’, een structuur uit de 1e eeuw v. Chr. die in de periode 1978-1989 onder leiding van professor Nimet…
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Inherited retinal degenerations: clinical characterization on the road to therapy
Prof. C.J.F. Boon Prof. N.E. Schalij-Delfos Summary: Erfelijke netvliesaandoeningen behoren tot een klinisch en genetisch heterogene groep aandoendingen, die in veel gevallen uiteindelijk leiden tot slechtziendheid of blindheid. Hoe de aandoening zich uit, kan erg variëren. Deze variatie kan…
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Complementary routes towards precision urologic surgery: image guidance technologies and standardized training programmes
PhD defence
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Family Matters
This dissertation describes the findings of six studies on mental health problems in the family context, specifically focusing on the associations with the parent-child relationship, parenting behaviors and experiences of childhood maltreatment. The aim is to better understand the risk factors, development…
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The Shadow Side of Positive Organizational Change
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Improving immunotherapy for melanoma: models, biomarkers and regulatory T cells
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Mining the kinematics of discs to hunt for planets in formation
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To Detain, or Not to Detain: A Functional Approach to Non-State Armed Groups’ Activities in Non-International Armed Conflicts
Dr. R.W. Heinsch Prof.dr. C. Stahn Summary: During armed conflict, non-State armed groups (NSAGs) deprive individuals of their liberty on a regular basis. Examples can be found in Colombia, Afghanistan, Libya, Syria, Mali and the Democratic Republic of the Congo (DRC), among many others. Yet,…
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From Noise to Insight: The Functional Role of BOLD Signal Variability and Aperiodic Neural Activity in Metacontrol
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Prof. T. Hankemeier Summary Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta. A number of phenotypes, including the aggregation of misfolded proteins, mitochondrial…
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Unravelling cell fate decisions through single cell methods and mathematical models
Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset. Therefore, we first focused on the discovery of cell types by single-cell RNA-sequencing…
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Statistical modelling of time-varying covariates for survival data
Prof. M. Fiocco Samenvatting Time-varying covariates are a challenging task in clinical research, as they represent dynamic patterns which affect patient's health status and disease progression. This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying…
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Lexical Tone in Word Activation
PhD defence
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Exploring Strange New Worlds with High-Dispersion Spectroscopy
Prof. I.A.G. Snellen Summary: Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic…
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At mission's end: The long-term impact of deployment on mental health
Prof. H.G.J.M. Vermetten Summary Dat een militaire uitzending tot mentale gezondheidsproblemen bij veteranen kan leiden is bekend, maar wat de impact is op de lange termijn is nog onduidelijk. In dit proefschrift worden de resultaten besproken van het PRISMO-onderzoek waarin een groep van duizend…
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Rights Denied, Heritage Stolen
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Advancing the evaluation of graduate education
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In between looking and seeing
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Immuno-photodynamic therapy of cancer
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Functional analysis of genetic variants in PALB2 and CHEK2
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Dynamics of Despair: Examining Suicidal Ideation Using Real-Time Methodologies
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Appropriation foncière, migrations agricoles et conflits armés en Pays Dogon (Mali)
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Reproductive and sexual health care in oncology
Prof. R.C.M. Pelger Summary: Oncologische behandelingen kunnen leiden tot vermindering van seksuele functie en vruchtbaarheid. In de loop der jaren is de overleving van de meeste soorten kanker dusdanig toegenomen dat seksualiteit en vruchtbaarheid na herstel zeer relevant zijn. Hoewel in het afgelopen…