Is the General Data Protection Regulation (GDPR) adequate in ensuring responsible innovation using data analytics? What is the role of ethics with regard to placing limits on technological developments? Does innovation drive business and industry transformations, or does shareholder value maximization…

Technology holds so much promise – from self-driving cars to enhanced physical performance from smart implants under the skin. But we should not let ourselves be caught off guard. That is the message of Bart Custers, Professor of Law and Data Science in his inaugural lecture on 21 May. ‘We don’t talk…

A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.

Biologist Laura Bertola argues that the traditional separation of lions into African and Asian subspecies is incorrect. She has discovered that Africa is actually home to two subspecies. Her PhD defense was on 18 March 2015.

For decades, scholars have wondered about the development and dissemination of languages around the world. What are the odds that peoples living thousands of miles apart speak varieties of Indo-European languages that are closely related? This riddle has now partly been solved thanks to an international…

Antibiotic-resistant bacteria are a major problem worldwide. Molecular biologist Changsheng Wu explored innovative methods of developing new antibiotics more simply and more easily. He also discovered a new type of antibiotic.

Using E. coli bacteria to convert a toxic compound in the soil on Mars into oxygen to make life on the planet possible. A team of thirteen Leiden students are taking part in the annual iGEM competition with an entry based on this idea. iGEM is an international competition for students where they use…

The idea that modern humans displaced Neanderthals because they were better protected against toxic smoke components is now under fire. An earlier study that put forward this suggestion has now been refuted by genetic research by scientists from Leiden and Wageningen. This new research was published…

There is greater variety in the size of men’s brains than of women’s. This could help explain why some psychiatric disorders such as ADHD and autism are more prevalent in boys. Leiden brain researcher Lara Wierenga has published an article about this in the international journal Cerebral Cortex.

Researching DNA material for genetic disorders using the most powerful apparatus. This is what GenomeScan, a company on the Leiden Bio Science Park, does. Master's student Konstantina Konstantinopoulou is doing an internship there. 'It's a world where developments happen really rapidly so it's a fantastic…

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

PhD defence

An incredible quantity of archaeological reports are stored in digital archives. If you want to search for information in them, you have to do this manually. And that is a real chore. Archaeologist Alex Brandsen has now used deep learning, a form of artificial intelligence, to develop a search engine…

Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.

Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…

Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

Lecture, Research Seminar

In a podcast of the Netherlands Internet Governance Forum (NL GF) and the Safer Internet Centre Nederland, Simone van der Hof, Professor of Law and Digital Technologies at Leiden University and Thijs Hannema, a lawyer at Kennedy van der Laan, discuss online privacy of children.

Recent developments in AI mean nobody is anonymous nowadays. The search engine PimEyes can find any photo of anyone that’s ever been placed online. No more Tinder Swindlers… or personal privacy. Everyone’s findable now. But is that even allowed?

PhD defence

As the flagship journal of the National Academy of Sciences USA, PNAS publishes several special features each year highlighting topics that are expected to engage the interest of the journal’s broad readership. Archaeologist Wil Roebroeks was invited by the Editors of PNAS to contribute a paper on the…

The Board of Governors is pleased to announce that Professor Cisca Wijmenga has been appointed by outgoing Minister of Education, Culture and Science Robbert Dijkgraaf as its new member.

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

With cancer, the immune system is a double-edged sword: it can attack tumour cells, but can also help them grow and spread. It is a question of harnessing it. This is what Professor Karin de Visser argued in her inaugural lecture on 15 November 2019.

To develop good cancer treatments, we need to know much more about how malignant tumour cells develop. Professor Ewa Snaar-Jagalska looks at not just the effect of medication on isolated cells but also the behaviour of cancer cells in their tissue environment. Inaugural lecture on 11 December.

Chris Jacobs, former PhD-student of the IBL, received the national “Dissertation Award” for best PhD thesis of the year on insects. The award was handed out last Friday, the 18th of December, by Professor Matty Berg, president of the Dutch Entomological Society.

A European consortium has provided a disruptive technological breakthrough to allow the discovery and characterization of novel enzymes for industrial biotechnology. The technology will open the way to more efficient industrial processes such as in the biofuel, animal feed and paper and pulp industr…

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

Conference, Workshop

In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Selected publications of the Cardiovascular and Metabolic Therapeutics group.

Bones contain information about people’s lives such as where they came from, their age at death and which diseases they suffered from. Researchers can deduce a lot from them about a person’s life and about human evolution. This generates leads that could help solve present-day problems, such as how…

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

The research programme Descriptive and Comparative Linguistics brings together LUCL researchers who focus mainly on descriptive and comparative linguistics.

How do we make tomorrow more sustainable, equitable, fair, and just? On the evening of 5 February scholars gathered in the conference room of Grand Café The Burcht to discuss this grand question at the Next444 Roundtable. Organized by the Young Academy Leiden as one of the final events of the Leiden…

A linguistic reconstruction of the migration of the Tocharians from Europe to China

The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

Research on the morality of life insurance. What issues are raised when insurance companies define responsibility and solidarity? Has insurance changed since the crisis of 2007?

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Lecture, This Time for Africa! Series

Lecture