On Wednesday 16 June 2021, Karim Khan was sworn in at the International Criminal Court (ICC) in The Hague. Experts say this is no easy time to join the ICC.

A next, general pharmacological problem to be tackled is how drug-target binding kinetics in vivo, affects target occupancy as an important indicator of the time-course of drug effects.

Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price

Harm reduction in practice: a comparative analysis of the Dutch and Brazilian approach towards drug users.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Discovery of metastasis promoting candidate drug targets

The research group War, Peace and Justice brings together scholars, researchers as well as current and former practitioners to explore issues related to the drivers, nature and (new) dynamics of war and conflict, comprehensive approaches to the promotion of sustainable peace, and the role of justice…

Why do some civil wars experience quagmire, a situation in which belligerents are trapped in fighting? To explain this puzzle, Jonah Schulhofer-Wohl (Leiden University Institute of Political Science) analyses the overlapping strategic interactions between foreign powers and the warring parties. Studying…

In the track War and Peace Studies, you will gain a thorough understanding of the history, theories as well as the contemporary and future policy challenges related to war, warfare, and the multidimensional promotion of peace.

In 1940 the Germany occupiers ordered the dismissal of all Jewish staff of the university. This resulted in protest speeches by fellow academics.

On 11 April 2018, students of the Advanced Master’s in European and International Human Rights Law attended a lecture on the human rights situation in Mexico. The lecture was delivered by Dr. Víctor Avendaño Porras, who lectures and researches at Mexico’s CRESUR (Research Centre on Teaching Formation…

Lecture

Lecture

Lecture

Lecture

In Freedom on the Offensive, William Michael Schmidli illuminates how the Reagan administration's embrace of democracy promotion was a defining development in US foreign relations in the late twentieth century.

Drugs-related violence in Mexico is similar in terms of dynamics and strategy to the IS hybrid war in the West. This is the claim made by Teun Voeten. PhD defence 20 September.

This book explores the lasting legacy of the controversial project by the Congress for Cultural Freedom, funded by the CIA, to promote Western culture and liberal values in the battle of ideas with global Communism during the Cold War.

Information about the situation in Ukraine

Cigdem Oguz defended her thesis on 13 June 2018

Lecture

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Leiden University commemorates its victims of the war and pays tribute to all members of the university community who resisted injustice. Rudolph Cleveringa, for instance, the dean of the law faculty who gave a protest speech in 1940 after his Jewish colleagues were fired. We honour their memory through…

Despite the wealth of historical literature on the Second World War, the subject of religion and churches in occupied Europe has been undervalued.

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.

Can we develop a generic method for Quan/Qual analysis of small molecule drugs, their metabolites and endogenous metabolites in (pre-)clinical samples?

Although rarely considered by the pharmaceutical industry or clinicians, 24-hour rhythms in physiology are a factor of potential influence on the pharmacokinetics and pharmacodynamics of drugs.

Another research line is the development of a spatial CNS drug distribution model, by ultimately including the 3-dimensional anatomical organization of the CNS.

How can we extend the drug residence time to combat diseases more effectively?

Salvador Santino Regilme has been selected for a fellowship at the Netherlands Institute for Advanced Study (NIAS) in Amsterdam. From September 2022, he will spend 5 months at NIAS working on his research project titled 'The Normative Order of the Global War on Drugs'.

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

Writing under Wartime Conditions is a study into North and South Korean literature written during the Korean War.

A new special issue on translation and the cultural Cold War sheds light on the understudied and yet important role of translation in cultural transfer.

Studies on the Ottoman Jihad on the Centenary of Snouck Hurgronje's

During the course of drug discovery translational steps are made.

Source: ChemMedChem (2015)

Heart failure is a major health care problem with high mortality.

Can effective synergists be identified to enhance the effect of antibiotics against Gram negative pathogens?

How was anti-communism organized in the West? New volume edited by Giles Scott-Smith, Luc van Dongen and Stephanie Roulin on the aims, arguments and associations of a range of transnational anti-communist activists during the Cold War.

On 1 September 2022 Güldeniz Kibris successfully defended a doctoral thesis and graduated.

From Apartheid in South-Africa to 9/11 in the United States: there is not a single culture that is not shaped by the memory of war or conflict. The minor Cultural Memory of War and Conflict focuses on how such memory cultures influence and shape societies today.

Data analysis with Python and R are rapidly becoming essential skills for modern scientists. Therefore, we are offering courses to develop your scientific computing skills. Those courses are optional for LACDR PhD candidates.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

On the 6th of March 2023, Santino Regilme presented his work-in-progress titled 'Global Drug Wars: Contested Normative Orders of Peace, Security, and Human Rights'. If the battle against illegal drugs is construed as a war, how is victory in such a war defined and constructed? If the oppositional…

This thesis seeks to examine the emergence of Persian novels and short stories during the Iran-Iraq War (1980-1988).

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

This volume provides an authoritative, cutting-edge resource on the characteristics of both technological and social change in warfare in the twenty-first century, and the challenges such change presents to international law.