Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

Promotores: H.A. Udo De Haes, P.M. Brakefield

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

For a successful implementation of an educational reform, teachers need to regard the proposal as being practical. I used a modular, success-oriented approach to make a context-based reform practical for implemtentation in Duthc biology education. educational reform, modular, teachers, biology, success-oriented,…

Roel Wouters (24), a biology student at Leiden University, is a finalist in the election for UN youth delegate for Biodiversity and Food. The digital polls open for a week on Friday 22 October. Under-30s can vote for Roel at www.stemroel.nl.

Paul Brakefield, Professor of Evolutionary Biology at the Institute of Biology in Leiden (IBL) has been awarded an ERC Advanced Grant for his research. He will receive 2.5 million euro to develop his research programme over a period of five years.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.

Ariane Briegel has been appointed Professor in the fìeld of Ultrastructural Biology within the Faculty of Science at the Institute of Biology from the 1st of December 2015. Her expertise is in using electron cryotomography to study how microbes sense and respond to their environment.

Biology is one of the four top educational programs at Leiden University according to the national “Guide to Universities” (Keuzegids Universiteiten).

Gijs van der Velden has one of the best study results in his first college year of all science studies. With that, he won the Young Talent Incentive award and received 500 euros of the Koninklijke Hollandse Maatschappij der Wetenschappen (KHMW). The biology student remains quite nonchalantly. ‘Of course,…

A Vici grant and a Science-GROOT: scientists from the Institute of Biology Leiden have been awarded prestigious grants from the Dutch Research Council (NWO). From investigating bacteria without cell walls to harnessing plants with the help of microorganisms.

‘It was not always accepted, but I just wanted to be a researcher. Now, I am as happy as can be.’ It is one of the quotes from the International Women’s Day presentation for Biology students. Seven women, working as researchers and teachers at the CML, IBL, and Naturalis, shared their experiences with…

The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…

On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

An external visitation committee gave the Institute of Biology Leiden (IBL) an outstanding assessment. In terms of research quality and relevance to society, the IBL gets the highest score: excellent. The increase with five new female professors also receives praise from the committee.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

In 2023, many of our students and staff won great prizes and secured important research grants.

Vera van Noort has been appointed Professor in the field of Computational Biology within the Faculty of Science at the Institute of Biology from the 1st of February 2017. Van Noort’s expertise is in bioinformatics and her research focuses on the computational analysis of large-scale biological data…

On February 24, 2017, the Institute of Biology Leiden organised the first edition of the Biology Career Event. The career event for third year bachelor and master students was well received by the attendants. ‘I felt that the presenters and people doing the workshops were really trying to help us get…

As of 1 July, Professor of Mathematical Biology Roeland Merks has got a full appointment at Leiden University. Before this expansion, he worked one day a week at the Mathematical Institute (MI). Merks will work half of his full appointment at the MI and the other half at the Institute of Biology Leiden…

150 new Biology students have arrived in Leiden. This is more than ever and we seem to settle among the big three Universities for Biology in the Netherlands.

The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…