1,238 search results for “computational modelling” in the Public website
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Yujie Li
Science
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Interview with Jaap van den Herik by BNVKI
Recently, Jaap van den Herik, professor emeritus Law and IT, was interviewed by the BNVKI (Benelux Association for Artificial Intelligence).
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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Let's Play Quantum Games
Lecture
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Assessing the safety of chemicals and medicines without laboratory animals
One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Preclinical and ‘near-patient’ models for the evaluation of experimental therapy in prostate and bladder cancer
PhD defence
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Vidi grant for Angus Mol: ‘Historical games are like time machines’
How do games help shape our perception of the past? Associate Professor Angus Mol receives a Vidi grant to answer this question.
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Enhanced coinduction
Promotores: J.J.M.M. Rutten, F.S. de Boer, Co-promotor: M.M. Bonsangue
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Pascal Professor 2015
In 2015 the Pascalchair of the Faculty of Science, Universiteit Leiden and in particular of Leiden Institute of Advanced Computer Science, is held by Prof. Dr. Natasa Jonoska, University of South Florida, Tampa, USA.
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Unraveling the Role of SOCS1 and HNRNPK through Genetically Engineered Mouse Models
PhD defence
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Engineering of new 2D materials phases not existing in nature / Surface computational astrochemistry on the formation and destruction of HCN and HNC-MSCA
Lecture
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615 million euros for quantum research
Quantum Delta NL, a research programme in which Leiden University participates, has been awarded 615 million euros from the National Growth Fund to help develop the Netherlands into a top player in quantum technology. This has been announced at the presentation of the honoured proposals in The Hague…
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Two young chemists win Marie Curie subsidy
The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…
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Cells with stress: predicting drug-induced liver and kidney damage
How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.
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Discoverer of the Year Paul Behrens: ‘We’re running out of time’
Earlier this year, the public voted environmental scientist Paul Behrens Discoverer of the Year 2018. Behrens is an interdisciplinary scientist who wants to understand our impact on the planet. ‘Unfortunately, we are not doing enough. Huge changes are underway and we’re running out of time to avoid…
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Awards for three Leiden Partnership projects with industry sector
NWO is funding three partnership projects with the industry sector. The projects relate to speeding up the search for new medicines, studying the changes in proteins as medicine and developing analytical techniques for research on the building blocks of life.
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New protein inhibitors against cancer? Unilever Research Prize for Aukje Beers
Aukje Beers combined theory and practice, as well as chemistry, biology, and computer models. In this way, she discovered two protein inhibitors during her master’s project that could contribute to the development of a new cancer drug. For her research, Beers received the Unilever Research Prize on…
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AI application in pathology reveals novel insights in endometrial cancer diagnostics
Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…
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New project uses artificial intelligence in drug development
In health care, artificial intelligence is quite normal: it is used, for example, as an aid in making diagnoses. However, artificial intelligence is not yet used as much in drug development. A new prestigious partnership is therefore going to investigate how artificial intelligence can contribute to…
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Rubicon (NWO) awarded to Dr. Quentin Bourgeois
A Rubicon Grant is awarded to dr Quentin Bourgeois for his reserach project
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Tomb 45 (Luxor, Egypt): some recent results on geo-referenced 3D modelling
Lecture
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Can Wang
Science
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How China will reduce its carbon impact
Rong Yuang, PhD candidate from the Institute of Environmental Sciences investigated the impact of the renewable energy expansion on China’s carbon emission. On 17 May, she will defend her thesis. China is investing heavily in the development of low-carbon electricity sources, like nuclear, hydro-,…
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Exploring the Universe
Astronomers want to understand the Universe, from the Big Bang to the present day, and what the future will hold. In Leiden they focus on two key questions: ‘How did stars and planets originate’ and ‘How were galaxies and black holes formed in the young Universe?’ A new generation of telescopes – just…
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Estimation and Optimization of the Performance of Polyhedral Process Networks
Promotor: E.F.A. Deprettere, Co-Promotor: A.C.J. Kienhuis
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Sizing up protoplanetary disks
This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.
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What do PAHs do in space?
Xander Tielens, Professor of Physics and Chemistry of the Interstellar Space, has been awarded an ERC Advanced Grant to study polycyclic aromatic hydrocarbons (PAHs) in space. The combination of astronomical observations, computer models and lab research makes the research highly interdisciplinary.
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The scent of the universe
Former PhD student Cameron Mackie will been awarded not one, but two dissertation prizes for his thesis on the aromatic universe. His work could provide us with a virtual sniff of space. ‘These molecules in space likely smell like a big charcoal grill!’
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This is how physicists use light to build complex structures
Petr Steindl works on quantum dots in microcavities for his PhD research. He manipulates single-photons to create complex structures of light. Applications could include quantum communication and gates for quantum computers.
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Chemistry can change the ingredients in planet formation
Which molecules go into forming planets? PhD candidate Christian Eistrup and his colleagues have created new models to research this question. Their findings could change our idea of which molecules were forming Jupiter or even Earth.
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Quantum optics for asylum seekers
The Clinical Epidemiology department at the LUMC has set up a series of lectures for asylum seekers. The series has become a huge success.
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Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists
Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)
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Public Lecture ‘The Role of the Humanities in an Information Age’ by Ted Underwood, Visiting Scaliger Professor
Leiden University Libraries invites you to the public lecture by Ted Underwood, Visiting Scaliger Professor. This lecture will be held on Thursday 21 November, from 16.00-17.00 in the Lipsius building, Room 0.19, Cleveringaplaats 1, Leiden. Afterwards, you can meet the new Visiting Scaliger Professor…
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Understanding metastasis: Science Groot grant for Erik Danen
A team led by Erik Danen from the Leiden Academic Centre for Drug Research has received a 3 million euros NWO Science Groot grant to unravel the first steps of metastasis. Danen will work together with biologists and theoretical and experimental physicists from Dutch Universities. ‘Understanding these…
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The Old Observatory Leiden in LEGO? You can make it happen!
Every week, Uwe Hensch walks past the Old Observatory in Leiden. In corona times, he decided to make a LEGO design of the historic building. His design is now finished and might go into production. You can help to make it happen.
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No humans needed: Neanderthals possibly responsible for their own extinction
Scientists remain puzzled by the sudden extinction of Neanderthals, some 40,000 years ago. New research by scientists from Eindhoven University of Technology, Leiden University and Wageningen University now suggests we might have been too quick in attributing the demise of Neanderthals to invasions…
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Mariska Kriek is back – but this time as a professor
She left Leiden after her PhD and now, 14 years later, she returns as Professor of Extragalactic Astronomy. Mariska Kriek investigates how galaxies originate and evolve. And she is eagerly awaiting the launch for the new James Webb telescope: ‘The coolest things we are going to find are those we’re…
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More-than-Planet exhibition gives perspective
What is Planet A? A new exhibition in the Old Observatory sheds light on how we all have different perceptions of earth. In five art installations, visitors are confronted with their own beliefs and how these differ from those of others.
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De Lange appointed Professor of Predictive pharmacology
As of 1 March 2018, Elizabeth (Liesbeth) de Lange has been appointed as Professor of Predictive pharmacology at the Leiden Academic Centre for Drug Research (LACDR). She is head of the research group Predictive Pharmacology and mainly aims at developing mathematical models that can predict the effect…
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Nienke van der Marel receives New Horizons Prize
Nienke van der Marel has been awarded the New Horizons Prize in physics for her pioneering research on planet formation. This prize is given to young, promising researchers in physics or mathematics. The astronomer and her colleagues found the first observational evidence for 'dust traps' in disks around…
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FameLab: all about blood vessels in 180 seconds
PhD candidates in medicine, Wouter Jan Geelhoed and Nan van Geloven, are the winners of the Leiden preliminary round of FameLab. They are through to the final on 22 April.
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Elena Maria Rossi continues her search for the origins of the largest black holes, but now as a professor
Elena Maria Rossi is fascinated by black holes. Her appointment as a professor was a long-held wish, partly because there are so few female professors in her field. ‘My appointment is also a milestone for the Leiden Observatory.’
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Leiden Medicinal Chemistry researcher Andreas Bender receives prestigious EFMC Prize
Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the
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New substances inhibit inflammation in the brain
Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…
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Erik Danen appointed as Professor of Cancer drug target discovery
As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.
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AI and Scientific Evidence: Rodrigo Ochigame's Transformative Research
Rodrigo Ochigame’s project explores how AI redefines scientific evidence, aiming to help scientists critically navigate these transformations with the Veni grant.
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Planet formation starts before a star is fully grown
A team of European astronomers under Leiden leadership has discovered that dust particles around a star already coagulate before the star is fully grown. These agglomerated dust particles are the first step in the formation of planets. The research publish their discovery in the journal of Nature As…
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Mismatched timing: how climate change challenges bird migration
How does climate change affect the migration routes of birds? Mainly negatively, according to a new study from Yali Si from the CML. ‘It changes the timing of natural events differently in each region,’ she explains. ‘This can lead to a growing mismatch between the availability of food and the supposed…
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Producing all our food nationally: is it even possible?
According to a new study, for half of the world population the answer would be yes. For the other half: maybe? Leiden environmental researcher and head author Nicolas Navarre explains: ‘With improvements to crop yields, reductions in food waste, and changes in consumption patterns, 90% of people could…