Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Can we develop new enzymes and cell factories to upgrade current enzyme cocktails towards complete degradation of biomass?

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: B. van de Water

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Three researchers from Leiden University have received awards in the Quantum Technology programme within the National Growth Fund, organised by NWO in collaboration with Quantum Delta NL. Read more about these three futuristic projects.

During the final event of the PRE-Class Rechtsgeleerdheid, secondary school pupils organised a mock trial on the impact of artificial intelligence (AI) on society. Together with the audience, they explored the possibilities and pitfalls of AI. ‘They all did a wonderful job.’

An overview of our infrastructure at the SPP division:

About the book

Our researcher and PhD candidate Helena Ursic was interviewed with Druzina, one of the biggest weekly newspapers in Slovenia.

On Wednesday 12 December 2018, the department of Child Law, on the initiative of dr. Yannick van den Brink, dr. Stephanie Rap en prof. dr. Ton Liefaard), organized an expert meeting on ‘Equality, children’s rights and digital technologies’. The objective of the meeting was an in-depth exchange of ideas…

Cutting down global emissions of greenhouse gases to combat global warming won’t do the trick alone: we also need negative-emissions technology that can capture carbon dioxide directly out of the air. In the prestigious journal Global Environmental Change, PhD candidate Oscar Rueda and colleagues shed…

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

How and to what extent does AI affect citizen representation in public service delivery and state-citizen interactions?

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

In November 2022, at the request of the House of Representatives, the Dutch Government established the State Commission on the Rule of Law.

Psychologists Emma ter Mors, Christine Boomsma and other research partners will share results from their work on the crucial issue of societal support for delivering carbon capture, utilisation and storage (CCUS) in Europe. You're welcome to watch the free webinar.

The crisis in Iran seems to have settled and both countries are claiming victory. The Americans say that they taught Iran a lesson, but Iran projects the contradictory. Now, who is right? On Thursday 9th January, Bert Koenders commented on this on BNR News Radio.

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

Students from eLaw completed a successful work experience programme researching contact tracing apps at Privacy Company in The Hague.

Promotor: Prof.dr. E. R. Eliel, Co-Promotor: M.J.A. de Dood

For some devout Muslims, going to the cinema or viewing certain images is provocative and problematic. Ahmad Nuril Huda investigated the development Santri (young, pious Muslims) have undergone in this field over the past ten years. The Cinematic Santri is the result of his PhD research.

Researchers at Leiden University have mapped genes that cause breast cancer cells to migrate. The Leiden toxicologists Professor Bob van de Water, Dr Wies van Roosmalen, Dr Sylvia E. Le Dévédec and colleagues studied 1500 individual genes. They found eight, including the SRPK1 gene, that regulate the…

Last week, the results of the 2016 call for proposals of the European Institute of Technology Raw Materials (EIT RM) became available. Both Leiden University and Delft Unversity of Technology are partners in this Knowledge and Innovation Community, in which some 100 research institutes, industries and…

Technological developments never stop. Machines can already perform many tasks and in the future they will probably take over even more of the work we do. Which jobs could disappear and which will remain in the future? Olaf van Vliet, Professor of Economics at Leiden Law School, commented on these issues…

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotores: J. Jonkers, K.E. de Visser

Vaccination via the skin or the mucosae

Ecotox is located in an ambitious surrounding at the Leiden University. It is an initiative of both institutes Institute of Environmental Sciences (CML) and Institute of Biology Leiden (IBL).

MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

The goal of target discovery is to identify and validate proteins and biological pathways that are involved in the disease process. Modulating these target proteins and pathways with small molecules, therapeutic proteins or other biomolecules (e.g. mRNA) could deliver an effective and safe drug or v…

The objective is to develop in vitro antigen degradation assays in order to mimic the fate of the antigen in vivo.

Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Lars Jeuken, Anne Wentink, Anjali Pandit, René Olsthoorn and Alia Matysik.

The rise of populist parties, the expansion of the role of the state and now the fragmentation of the Senate and the House of Representatives: Dutch political reality has changed rapidly over recent decades. These developments are in stark contrast to Dutch constitutional law that has remained almost…

The imaging group focuses on bio-imaging, image analysis and visualization.

The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.

We investigate reaction systems, a novel computational model gleaned from the biochemical reactions taking place in living cells and information processing in nature.

How can the transport of molecules in living cells help to target medicines at exactly the right place?

How do plant defense genes get activated?

Individual traders should be at the forefront of the study of early modern world trade rather than institutions such as states and companies, argues Professor of Global Economic Networks Cátia Antunes. Inaugural lecture on 9 June.