10,000 search results for “studies” in the Public website
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CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Segments and rules: a comparative study into the computational mechanisms underlying language acquisition
In this project we study the properties of statistical- and rule-learning mechanisms in relation to the acquisition and evolution of language. We ask to what extent these mechanisms are unique to humans - or to human language - by comparing the acquisition of vocal structure in two species: humans (infants)…
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Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
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A Sociolinguistic Study of an Ewe-based Youth Language of Aflao, Ghana
On the 26th of September, Cosmas Rai Amenorvi successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Cosmas on this achievement!
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Synthetic peptides, nucleic acids and molecular probes to study ADP-Ribosylation
This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.
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A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context
In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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Ælfric’s Afterlives: Copying, Editing, Studying, Teaching and Remembering the Most Prolific Author of Old English
Conference
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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The SMILE study: Sleep Mood lntervention: Live Effectively a group intervention in students with sleep problems
Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?
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The development of tools to study the interplay between Ubiquitination and ADPribosylation
PhD defence
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Innovative (electro-driven) sample preparation tools for metabolomics study of muscle aging
This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.
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Towards responsible and resilient mineral supply chains, with case studies on cobalt, antimony, and zinc
PhD defence
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‘Suspect community or suspect category?‘, Journal of Ethnic and Migration Studies
Ragazzi, ‘Suspect community or suspect category?‘, Journal of Ethnic and Migration Studies
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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conservation using hyperspectral and lidar data; Oostvaardersplassen as a case study
This project aims to develop advanced data analysis methods for monitoring and increasing our understanding on biodiversity dynamics in nature reserves such as the Oostvaardersplassen.
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galaxies at low frequencies: high spatial and spectral resolution studies with LOFAR
Promotor: H.J.A. Röttgering, Co-promotor: G.K. Miley
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A mathematical three-step rocket helps biologists study tumour blood vessels
Koen Keijzer combined three mathematical models into one unified system capable of making meaningful predictions about how cells form blood vessels. This helps biologists studying the chaotic, leaky blood vessels found in and around tumours.
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Ajay Gandhi
Faculty Governance and Global Affairs
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Deniz Tat
Faculty of Humanities
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David Henley
Faculty of Humanities
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James McAllister
Faculty of Humanities
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Lena Riecke
Faculty Governance and Global Affairs
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Onur Ada
Faculty of Humanities
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Omer Kocyigit
Faculty of Humanities
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Elly Mulder
Faculty of Humanities
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Ugur Derin
Faculty of Humanities
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Towards in-cell structural study of light-harvesting complexes : an investigation with MAS-NMR
Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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Studies in Tocharian verbal morphology relevant to the cladistic position of Tocharian in Indo-European
On the 24th of September, Louise S. Friis successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Louise on this achievement!
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
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Working on Labor. Essays in Honor of Jan Lucassen | Studies in Global Social History, Volume: 9
This collection of seventeen essays takes its inspiration from the scholarly achievements of the Dutch historian Jan Lucassen. They reflect a central theme in his research: the history of labor.
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Computational, biochemical, and NMR-driven structural studies on histone variant H2A.B
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.
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Tapping into semantic recovery: an event-related potential study on the processing of gapping
This project aims to investigate the underlying (neurocognitive) linguistic processes of ellipsis resolution, particularly gapping.
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Democratic Secrecy: A Philosophical Study of the Role of Secrecy in Democratic Governance
The starting hypothesis of the project is that secrecy is not always inimical to democratic governance as conventional wisdom has it.
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi
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A study of Polish LDS (Mormon) conversion in two branches in Warsaw, Poland
On the 16th of June Patrtick Harrison successfully defended a doctoral thesis and graduated.
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Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.
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Smoothly breaking unitarity : studying spontaneous collapse using two entangled, tuneable, coherent amplifiers
The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.
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The Urban Graveyard
The urban graveyard presents several studies in which the results of older archaeological and osteoarchaeological research are compared to more recent excavation data from several Dutch, Belgian and Danish cities and towns.
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Improving PTSD treatment for adults with childhood trauma (IMPACT-study)
The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with childhood abuse related PTSD. The ultimate goal is to improve quality of care and contribute to treatment innovation for this severely ill target population.
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The Metamorphosis of Change: A Study of Plato’s Theory of change
PhD defence
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Simon van der Straten
Faculteit Archeologie
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Challenging the paradigm of filthy and unhealthy medieval towns
Mapping sanitary infrastructure in large urban societies in the Low Countries, 1200–1900
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Smart Courts, Smart Justice? Automation and Digitisation of Courts in China
On Tuesday 3 September 2024 Straton Papagianneas successfully defended a doctoral thesis and graduated.
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Lieke Bes
Faculteit Archeologie
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Jade from the other mountain: Chinese fan fiction based on English source texts
On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.
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Erik-jan Zurcher
Faculty of Humanities
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Elpine de Boer
Faculty of Humanities