Promotor: Prof.dr. E.F. van Dishoeck, Co-promotor: S. Bruderer

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

In our lab, we investigate the physics and material properties of low-dimensional systems.

The Biology and SCS master specialisation gives you the opportunity to combine fundamental Chemistry research with different aspects of science communication.

Combine biology research with different aspects of business studies. Learn to build bridges between science and business.

On 16 January student Lisa Bruil from the Institute of Biology Leiden was awarded the annual prize from the Stichting Prof. dr. K. Bakker-Fonds for her outstanding results as BSc-student.

Projects in the department of Environmental Biology

The Leiden students who participated in the iGEM synthetic biology competition have won the prize for best production. They developed a way to have bacteria produce the substance suckerine, a protein derived from the Humboldt squid. By doing so, they want to help heal burn wounds. ‘The announcement…

The ‘Stans Prize 2010’ has been awarded to Leontien Cenin and Lisanne Daniëlle Korpelshoek for their research on impacts of landuse on three migrant harriers in northern Cameroon.

On this page you can read about our keynote speakers.

Do you have questions about the Master Biology? Please contact us!

Lecture

PhD defence

Chair of LU-European Center for Chinese Medicine and Natural Compounds, Institute of Biology, Leiden University - the Netherlands

Do you have questions about the Biology master’s programme? Please contact us.

Merijn de Bakker and colleagues of the IBL-research group of Prof. Mike Richardson provide a unique view on digit evolution in crocodiles and birds in their recent study published in Nature.

Hass

Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.

Lecturer at Leiden University, Mathematical Institute and Institute of Biology, Leiden - the Netherlands

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

Collaborators and advisors of the Plant BioDynamics Laboratory

Find out how to apply for Evolutionary Biology at Leiden University by following our step-by-step guide.

Find out how to apply for Biology at Leiden University by following our step-by-step guide.

Find out how to apply for Biology and Education at Leiden University by following our step-by-step guide.

Our education programmes span the entire spectrum of Animal Sciences, Evolution, Biodiversity and Conservation, Microbial Biotechnology and Plant Sciences.

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

Professor Fons Verbeek of the computer science and biology institutes at Leiden University has the fascination to visualize everything we can not see immediately. At SleutelstadFM he tells us that by converting 2 dimensional (2D) images to 3 dimensional (3D) structures, research is carried out into…

The Metabolomics Facility of the University of Leiden has brought together two research groups from the Faculty of Science that are well-known for their expertise in two different fields: the Biomedical Metabolomics Facility Leiden, experts in clinical metabolomics and the Natural Products Laboratory,…

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Calamus javensis is polymorphic. Morphometry and molecular approach resulted in all names used in the complex are regarded as synonyms of C. javensis except C. tenompokensis, which is retained as a distinct species. One variety is here recognized, C. javensis var. polyphyllus (including C. acuminatu…

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Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…

Dishoeck

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Source: PLoS ONE, Volume 10, Issue 3 (2015)

Grants awarded to molecular physiology research

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…