Drawing is one of the most unique human behaviours. Like language, drawing is a mode of communication and a cognitive tool that from an early age allows us to interact with others. Is the early development of drawing skill influenced by the social environment? If so, how?

ADHD&ME aims to explore how enhancing self-esteem can break the relation between ADHD symptoms and comorbid disorders, such as anxiety and depression. In this study we assess the effectiveness of a Cognitive Behavioural Therapy (CBT) program called Competitive Memory Training (COMET) for improving self-esteem…

The new CML minor Sustainable Development started on Monday 7 September 2009 with an official opening by the Vice-Rector Prof. Rietje van Dam.

The most famous monument of the Dutch Golden Age is undoubtedly the Amsterdam Town Hall by architect Jacob van Campen inaugurated in 1655.

This article discusses the coevolution of several species of the tribe Phyllantheae and moths of the genus Epicephala.

How are digital risk-profiles developed and used in practice?

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

On the 24th of October, Nurenzia Yannuar successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Nurenzia on this achievement.

For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food.

Do you want to know more about Cultural Anthropology and Development Sociology and what it is like to study in Leiden? Come to our online or on campus information events.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Imami Shiʿism was a key part of the turbulent thesis and antithesis which formed Islam, and it remains greatly influential today. The aim of the ImBod project is to write the first comprehensive social history of the Imamate.

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Can we develop new enzymes and cell factories to upgrade current enzyme cocktails towards complete degradation of biomass?

The potential of liposomal cancer vaccines

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Religion, Class, and the Postwar Development of the Dutch Welfare State. Dennie Oude Nijhuis.

EU foreign policy has become increasingly politicised over the past years, amongst others as a consequence of the succession of crises. Crises may engender processes of crisis framing and contestation. This article focuses on how the policy demands being voiced in these processes of contestation are…

The Netherlands Organisation for Scientific Research (NWO) has made a subsidy of 17 million euros available to further develop a Netherlands network for electron microscopy (NEMI). The network comprises five UMCs and eight universities, with Utrecht in the coordinating role. From Leiden, the Institute…

On the 22nd of February, Ami Okabe successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Ami on this achievement!

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Schneider