95 search results for “selection mutism” in the Public website
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Part-time silence: children with selective mutism
Livia, aged 7, was in class four. She loved to chat and was good at reading aloud. At least, at home. At school she never read aloud and she hadn't spoken a single word. What was going on? Selective mutism was the subject of the inaugural lecture by Maretha de Jonge, Professor by Special Appointment…
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Maretha de Jonge
Faculteit der Sociale Wetenschappen
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Education and Child Studies
The Leiden Institute of Education and Child Studies aims to conduct high-quality research that addresses major social issues. This inspires its BSc, MSc and PhD programmes.
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Selectivity
Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.
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Selection & Placement
The Bachelor programme Psychology will admit a limited number of students (Numerus Fixus). A selection process will determine which applicants best fit our programme. Also, it is a good way for you to discover if Psychology in Leiden is the programme for you. Please note: the selection process for…
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Selecting courses
Exchange selecting courses and projects
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Application & selection
Are you interested in participating in a PRE-Class? Then you need to write a motivation letter and complete an application form. Make sure you have permission from your school to participate.
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Application, selection and placement
Our selection and placement procedure starts with your application and ends with—hopefully—an invitation to you to enrol as an IRO student. This page tells you all you need to know about the steps to be taken in between.
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Application and selection
All applicants for LUC go through a selection process. You enter the selection process by applying in Studielink and submitting a complete application in the Leiden University application portal.
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Application and selection
You can apply for our new cohort between 1 and 30 September 2024. Fill in our form of interest to stay tuned!
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Admission and selection
Every year, the Young Academy Leiden looks for new members. We alternate between an open vacancy, to which candidates can apply, and nomination by the Faculty Boards and the Executive Board of LUMC.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Proteins in harmony: Tuning selectivity in early drug discovery
This thesis describes the importance of being able to control the selectivity of potential drug candidates.
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Discovery of selective diacylglycerol lipase β inhibitors
Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…
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Reactivity and Selectivity in Glycosylation Reactions
The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.
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Material constraints of selected energy pathways
Examining if large scale application of new energy pathways can be constrained by materials and emissions.
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Selectivity and competition between the anodic evolution of oxygen and chlorine
Sustainable energy from wind and solar is most readily available near the sea.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Selective and efficient electrochemical CO2 reduction on nanostructured catalysts
Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink
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Promoting Legal Certainty and Increasing Judicial Skills in Selected Areas
How can the legal and socio-legal research skills of Indonesian jurists be increased in order to promote legal certainty and to strengthen the capacity of the judicial training in the country?
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Bureaucratic Selection and Politics: Evidence from Teachers in Brazil
Does becoming a public sector employee change a person’s political beliefs, behaviors and interactions with the state? Do public teachers hold the same values as other professionals and the general Brazilian public?
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EU Foreign Policy in practice: selected cases from Latin America
Both Europe and Latin America face challenges globally and at home. Conflicts over land and resources have been resurgent in recent years.
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Marking the Default. Auxiliary selection in Southern Italian dialects
This dissertation focuses on the overt marking of φ features encoded on perfective active auxiliaries in a group of Southern Italian dialects.
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A Selection of the Poems of Sir Constantijn Huygens (1596-1687)
A Selection of the Poems of Sir Constantijn Huygens (1596-1687) was published in July 2015, edited and translated by Adriaan van der Weel and Peter Davidson.
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pharmacotherapy in paediatric epilepsy : the path to rational drug and dose selection
The path to rational drug and dose selection
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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On the road to justice: some selected suggestions for the future of Social Justice Research
In September 2023 Social Justice Research, a journal from Springer Nature, published a ‘Special Issue on Veteran Reflections’. Eight ‘veterans’ analysed the current status of justice research and suggested new directions and refinements. Herman Steensma, guest member of the section Social, Economic…
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Algorithm selection and configuration for Noisy Intermediate Scale Quantum methods for industrial applications
Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.
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Willem Meilink
Science
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Van Vonno, ‘Moving up or down: parliamentary activity and candidate selection’
How do parliamentarians secure their political future? Are their activities in the legislature connected to their place on the candidate list from one election to the next? Political scientists Tom Louwerse and Cynthia van Vonno examine the Dutch case. Their main finding is that speaking in the plenary…
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Surface Reactivity of Activated CO2 Selective use of energy in splitting CO2
Juurlink
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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Liposome-based vaccines for immune modulation: from antigen selection to nanoparticle design
PhD defence
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Selective electrochemical H2O2 production by a molecular copper catalyst: A crucial relation between reaction rate and mass transport
Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…
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oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)
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Adriaan IJzerman
Science
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Students selected for INET workshop
FGGA students Amber Klompmaker (Master in Public Administration) and Imogen Liu (Research Master in Political Science and Public Administration) have been selected to participate in the Political Economy of Capitalism workshop of the Young Scholars Initiative of the Institute of New Economic Thinking…
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EUniWell selected as 'European University'
EUniWell –the European University for Well-Being in which Leiden University and six other universities collaborate – is among the consortia selected for funding in the ‘European Universities Initiative’. The alliance will receive funding of 5 million euros from the European Commission.
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The hunt for selective drugs
How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…
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Sebastian Pomplun
Science
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Characterization of cancer-related somatic mutations and identification of a selectivity hotspot in adenosine receptor
G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.
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From decentral selection procedures to ICT projects
On 14 and 15 March, students can register as candidates for a place in the University Council (UR) or one of the faculty councils. But what do these participation bodies do? UR member Femke van der Meulen takes us through the agenda for the next meeting.
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First members of Young Academy Leiden selected
February 2019 will see the launch of the Young Academy Leiden (YAL). Founded by the Leiden members of De Jonge Akademie of the Royal Dutch Academy of Arts and Sciences, the YAL has been designed to support the university’s talented early career scholars.
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Olga Kepinska selected for the Merit Abstract Award
The OHBM Program Committee selected LUCL's Olga Kepinska to receive a Merit Abstract Award for the 2016 OHBM Annual Meeting in Geneva, Switzerland.
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Convergent molecular evolution of toxins in the venom of advanced snakes (Colubroidea)
The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…
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Selection architect first step new beta-campus
Leiden University has selected an architect for the realisation of its new beta-campus. As a team, Designers bureau Inbo in Rotterdam and JHK Architects have won the tender for phase 1, the new housing estate for the Faculty of Science.
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The Yenching Academy selects Honours Student of LUC The Hague
Sylvie Ramakers of Leiden University College The Hague has been accepted to the prestigious Yenching Academy of Peking University in Beijing China, making her the third LUC alumnus in five years to break the ceiling of the notoriously competitive selection.