Promotor: W.T. de Groot

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Promotores: Prof. dr. G.R. (Geert) de Snoo, Dr. E. (Ester) van der Voet

How can we assist Universitas Indonesia's department of International law to improve their educational and applied research programs on Transnational Law, Asset Recovery and International Investment Arbitration, with an eye on Indonesia’s security and rule of law reform agenda and the needs of the…

-

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer

New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Wrenching poverty, global inequality, violent political and ethnic strife, deadlocked, unresponsive or even collapsing governments, growing dissatisfaction with democracy and missed opportunities for innovation – these are merely some of the challenges of governance and development with which our programme…

On 30 September 2021 Babette van Hazebroek defended her thesis 'Understanding delinquent development from childhood into early adulthood in early onset offenders'. The doctoral research was supervised by Prof. J.W. de Keijser and Prof. A. Popma (VUMC).

What are the social, cultural, and/or educational consequences and challenges linked to the introduction of the international bachelor's programme in Cultural Anthropology and Development Sociology?

On 25 January 2024 H.J. Pak successfully defended a doctoral thesis and graduated.

In this opinion article published in World Development, the authors present five research and policy priorities. While it is clear that ‘pluriversal’ designs need to guide the way forward (Kothari et al 2019), defining a set of key pillars can provide direction and purpose across this pluriversality.…

Student agency is defined as the ability to increasingly take control of the learning process. It is associated with better grades, well-being, motivation and self-confidence. This research aims to provide teachers tools to stimulate student agency and to monitor its growth.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.

This dissertation reports on the requirements for the design and development of teacher assessments, and examines the possibility of developing an assessment procedure that complies with the formulated requirements.

Dissertation

How can we culture an artificial vascular network to support tissue development ex vivo?

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.

This thesis aims to address offshore wind energy (OWE)-related environmental impacts.

This thesis reports on the influence of induction programs on beginning teachers’ well-being and professional development, and the essential characteristics of an induction program. These topics were explored by means of an interview study and large scale survey study.

Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.

How can zebrafish research help to understand and fight human cancer?

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotor: J.N. Kok, Co-promotor: F.J. Verbeek

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Drawing is one of the most unique human behaviours. Like language, drawing is a mode of communication and a cognitive tool that from an early age allows us to interact with others. Is the early development of drawing skill influenced by the social environment? If so, how?

This article discusses the coevolution of several species of the tribe Phyllantheae and moths of the genus Epicephala.

How are digital risk-profiles developed and used in practice?

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

On the 24th of October, Nurenzia Yannuar successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Nurenzia on this achievement.

Do you want to know more about Cultural Anthropology and Development Sociology and what it is like to study in Leiden? Come to our online or on campus information events.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…