1,776 search results for “development disease” in the Public website
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Novel receptor concepts
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Systems pharmacology of the endocannabinoid system
What are the functions of the endocannabinoid system?
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Ayokunu Adedokun
Faculty Governance and Global Affairs
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Jacqueline Vel
Faculteit Rechtsgeleerdheid
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Carolien Rieffe
Faculteit der Sociale Wetenschappen
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Sjoerd Lopik
Faculteit Rechtsgeleerdheid
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Merijn de Bakker
Science
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Jonathan Phillips
Faculteit der Sociale Wetenschappen
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Stephanus Huijbregts
Faculteit der Sociale Wetenschappen
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Joost Visser
Science
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Jochanan Veerbeek
Faculteit der Sociale Wetenschappen
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Horst Fischer
Faculteit Rechtsgeleerdheid
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Paul van den Broek
Faculteit der Sociale Wetenschappen
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Xiaoyang Zhong
Science
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Jan Michiel Otto
Faculteit Rechtsgeleerdheid
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Maximilian König
Faculteit der Sociale Wetenschappen
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Bert Koenders
Faculty Governance and Global Affairs
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Lina van Drunen
Faculteit der Sociale Wetenschappen
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Alette Vonk
Faculty of Humanities
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Rizal Shidiq
Faculty of Humanities
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Medical Biochemistry
Medical Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University. The section is headed by Prof. Dr. Hans Aerts.
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Mapping Medieval Malaria
This research project studies the distribution and impact of medieval malaria in the Netherlands.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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The historical development of the Dutch posture-verb progressive construction
On the 22nd of February, Ami Okabe successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Ami on this achievement!
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Animal sciences and health
In the research theme ‘Animal Sciences and Health’, we work with various animal species to gain insights into fundamental biological processes in both animals and humans.
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Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
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Data Analytics and Management
Our group is part of the Metabolomics and Analytics Centre where we accompany the data from its acquisition all the way to the publication of identified associations and biomarkers for a range of human diseases. The generated data of the metabolic measurements are assessed using an in-house quality…
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Frank Schaftenaar
Science
- Leiden Academic Centre for Drug Research
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Forces and symmetries in cells and tissues
The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.
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Knowledge development of secondary school L1 teachers on concept-context rich education in an action-research setting
This thesis reports on a study that examined the development of L1 teachers’ practical knowledge when they researched and implemented concept-context rich education in an action-research setting.
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Subang: An Indigenous Institution for Sustainable Community-Based Development in the Sunda Region of West Java, Indonesia
This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.
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e-Coach: Tailored cognitive-behavioral e-Health care for patients with chronic somatic conditions
The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.
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About the programme
To maximise your personal development, we ensure tutorials are small-scale and staff members extremely accessible. In year one, you’ll have an average of 12 contact hours, half of which comprise lectures (in English) and the remainder tutorials (optionally Dutch or English).
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Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
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Bio-Pharmaceutical Sciences (MSc)
The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.
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Parkinson Protein α-Synuclein Binds Surprisingly Strong with Membrane
Α-synuclein, a protein associated with Parkinson’s disease, proves to bind with membranes in a surprisingly efficient way. It confirms scientists’ suspicion of the protein’s leading role in the transmission of neurotransmitters between nerve cells in the brain. Publication in PLoS ONE.
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Surya Tjandra defends his Ph. D thesis ‘Labour Law and Development in Indonesia’ on 4 February 2016
In his thesis Tjandra analuses the development of labour law in Indonesia. He focusses on the developments after the fall of the Soeharto regime (1998), the so called reformasi period.
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and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries)
The Power and Pains of Polysemy: Maritime Trade, Averages, and Institutional Development in the Low Countries (15th–16th Centuries) investigates the development of General Average and other so-called Averages in the Low Countries on the eve of the early modern period, showing how the various varieties…
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The synthesis of chemical tools for studying sphingolipid metabolism
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.
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Discovery of FLT3 inhibitors for the treatment of acute myeloid leukemia
The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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RE-PAIR: Unravelling the Impact of Emotional Maltreatment on the Developing Brain
What role do parent-child interactions play in the development, maintenance and treatment of depression in young people?
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The Development of the Pivot State Concept Based on Mackinder’s Heartland Theory
The research addresses the question of “what is the impact of geopolitical changes to the pivot states in the Middle East? With special focus on Turkey, Iran and Saudi Arabia.”