775 search results for “genetics he modification” in the Public website
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Role of Chemokine Gradient Sensing in Ewing Sarcoma Progression, Angiogenesis and Immune Targeting
What are the biological and biophysical mechanisms that control chemokine gradient sensing and migration of immune, endothelial, and tumour cells in tumour development?
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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Moralising Misfortune: A comparative anthropology of commercial insurance
Research on the morality of life insurance. What issues are raised when insurance companies define responsibility and solidarity? Has insurance changed since the crisis of 2007?
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Next444 Roundtable Report
How do we make tomorrow more sustainable, equitable, fair, and just? On the evening of 5 February scholars gathered in the conference room of Grand Café The Burcht to discuss this grand question at the Next444 Roundtable. Organized by the Young Academy Leiden as one of the final events of the Leiden…
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Descriptive and Comparative Linguistics
The research programme Descriptive and Comparative Linguistics brings together LUCL researchers who focus mainly on descriptive and comparative linguistics.
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The Tocharian Trek
A linguistic reconstruction of the migration of the Tocharians from Europe to China
- Admission & Application
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Programme structure
The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.
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PhD student in Plant - Microbe symbiosis
Science, Institute of Biology Leiden (IBL)
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Leiden Professor Cees van den Hondel appointed ‘Officier in de Orde van Oranje-Nassau’
Cees van den Hondel, IBL-professor and 2010 Programme director of the Fungus programme of the Kluyver Centre received the royal distinction
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National and international media attention for longevity gene
A publication in Nature Plants by a team of Leiden biologists has received national and international media attention. The researchers can have annuals flower multiple times thanks to a particular gene they discovered.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Anne Miers investigates public speaking anxiety treatments with new grant
Developmental psychologist Anne Miers of Leiden University is involved in a large-scale research project investigating the efficacy of interventions regarding social skills, resilience and insecurity. The project is funded by a grant from The Netherlands Organisation for Scientific Research - Health…
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Aart Strootman’s research outcome premieres at Spring Festival 2022
On April 4 a new composition and a new instrument by researcher Aart Strootman will see the light of day at the 55th edition of Spring Festival 2022, presented by the Royal Conservatoire’s Composition department.
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Veni grant Lucien van Beek
The Netherlands Organisation for Scientific Research has awarded dr. Lucien van Beek a Veni grant. This grant offers young researchers the possibility to develop their innovative ideas for a period of three or four years. The awarded research proposal focuses on the Ancient Greek dialects' contribution…
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Unilever Research Prize 2015 for Biologist Flor Rhebergen
On December 4th, Flor Rhebergen received the 2015 Unilever Research prize for his study achievements at the IBL for his outstanding work in the field of Evolutionary Biology. Flor Rhebergen received the “Ovum” sculpture and was awarded €2.500.
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NWA grants for interdisciplinary consortia
Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…
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Spinoza Prize for Leiden statistician Aad van der Vaart
Aad van der Vaart, professor of stochastics at Leiden University, has been awarded the NWO Spinoza Prize for his groundbreaking research in statistics. Van der Vaart conducts fundamental research on models that can help, for instance, to identify genes that play a role in cancer.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Hortus Leiden helps to protect plant diversity around the world
The Global Strategy for Plant Conservation, a world-wide effort by the botanist and plant protection community, is making considerable progress in protecting plant diversity around the world, a new report says. The Hortus botanicus Leiden is one of the partners of the project.
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Collaborating bacteria sacrifice themselves for the greater good
Like ants, termites and bees, some bacteria work together as a multicellular group. There is a strict division of labour in such colonies, to make the group more resilient to the outside world. Now researchers have found that some parts of the bacterial colony can take ‘for the greater good’ to a whole…
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Translating science into treatments of rare metabolic disorders
Leiden biotech startup Azafaros has successfully completed a funding round, raising 25 million euros of investments for developing treatments of rare metabolic disorders. The company holds exclusive license to a library of novel patented compounds discovered by experts from Leiden University.
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How fungi are helping us be more sustainable
Professor of Fungal Genetics and Biotechnology Arthur Ram explains how fungi can help us be more sustainable.
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Cities have a direct influence on evolution
A global biological study has provided the most direct evidence to date that humans, and specifically cities, are the drivers of evolutionary change on Earth. Leiden University, Naturalis and the Municipality of Leiden worked on and helped fund the study.
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How ‘sleeping’ microorganisms can determine the fate of a population
Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.
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How brain disorder models are like the Night Watch
Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.
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NWO grants two IBL-proposals by interdisciplinary research consortia
Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.
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Seventeen million for Dutch X-omics Initiative
The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.
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Cum laude PhD defence: natural seed bank drives diversity
Each year, poppies disperse seeds that grow into a new generation of flowers. Sometimes, some of the seeds postpone their germination for a few years, for example when they’re covered by a layer of sand. Only when the sand disappears, do they start to sprout. Margriet Oomen did mathematical research…
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Adapting to climate change: mutation enables flour beetles to speed up their development
Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.
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Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.
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Student team hopes to heal skin with squid protein
Eleven ambitious Leiden students hope to heal burns with a special substance from squid teeth. They are taking part in the international iGEM competition. They need to raise almost 10,000 euros to fund their project this summer.
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The whole world is studying in Leiden
An impressive 1,300 international students from 84 different nations got to know each other at the University in Orientation Week Leiden. Where do they come from and why did they choose Leiden?
- Publication highlights
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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Deciphering the link between Iron and Brain Disease
Aceruloplasminemia is a very rare, genetic disease accompagnied with iron accumulation that causes movement disorder and brain damage at early age.
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Mapping of bacterial genomes to combat infectious diseases
Mapping of bacterial genomes to combat infectious diseases
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Thomas Bäck wint IEEE Award
Thomas Bäck wins the 2015 IEEE CIS Evolutionary Computation Pioneer Award for his contributions in synthesizing evolutionary computation.
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Increase the impact of your knowledge with MOOC ‘Knowledge Exchange: Using, Protecting and Monetizing Ideas with Third Parties’
Interested in how you can transfer your knowledge from yourself or from a knowledge institute into society at large? Several experts in the fields of grant development, Intellectual property rights and knowledge brokering take you through the various processes within four weeks time in this online c…
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Material Culture, Consumption and Social Change
New Approaches to Understanding the Eastern Mediterranean during Byzantine and Ottoman Times
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Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
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Postdoctoral Researcher on the Adaptive Capacities of States to Transboundary Crises
Governance and Global Affairs, Institute of Public Administration
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YAL members
Read all about YAL membership and the members of the Young Academy Leiden.
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Evidence - fact finding
The Leiden faculty has a lively tradition in the field of criminal truth finding and evidence.
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Teaching
Research projects for students of the University of Leiden and other Dutch Universities are often available at the MacBio group. The research lines are also described in the Research section. For details of specific projects contact the supervisor (Ubbink, Dame, Boyle, Jeuken or Wentink).
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Hall of Fame 2021
In 2021 many of our students and staff won fantastic prizes and were awarded important research grants. This is our traditional review of these successes as the end of one year marks the beginning of another.
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Tracking the Tocharians from Europe to China: a linguistic reconstruction
This project intends to provide an integrated linguistic assessment of the hypothesised migration route of the Tocharians.
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…