191 search results for “replication” in the Public website
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Replicate yourself in the ‘Virtual Identity Lab’
How do humans construct their self?
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Replicated molecules reveal hiding method of bacteria
Specific fatty acid-sugar molecules allow leprosy bacteria, among others, to hide from our immune system. How exactly is not entirely clear. Hessel van Dijk, who received his PhD on 13 October, replicated the molecules, helping to solve a piece of the puzzle. Van Dijk's dissertation is titled: Synthesis…
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NWO Open Competition for replication research: 'Deals with fundamental question in my field'
Innovation through repetition. That is how university lecturer Jurriaan Witteman describes his research on the automatic processing of angry voices in the brain. The original research was conducted 20 years ago, but, with an NWO grant, Witteman is now going to see if those results are accurate.
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‘Nothing is so special about human intelligence, that it cannot be replicated in a machine’
Is the possibility of computers making decisions for us in the future realistic? Holger Hoos, professor of Machine Learning, gives his opinion about the future of artificial intelligence in the television show ‘The future is fantastic’ on NPO3.
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Jurriaan Witteman
Faculty of Humanities
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Open Science Coffee: Non-replication pathways
Lecture
- Open Science Coffee: Non-replication pathways
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High fidelity DNA replication and repair
PhD defence
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Does the human brain process angry voices automatically?
Using brain imaging to discover the area in the brain that recognizes emotion.
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Identifying and characterizing regulators of histone acylation and replication stress
PhD defence
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Control of replication associated DNA damage responses by Mismatch Repair
PhD defence
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Characterization of DNA-replication proteins and their molecular mechanisms
PhD defence
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Cellular cryo-tomography of nidovirus replication organelles
PhD defence
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Meindert Lamers
Science
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Completed Studies
Below you can read about studies we have carried out in the past.
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Bacterial Chromatin
The relative simplicity of the bacterial cell, short generation times and well defined and inexpensive culturing conditions have significantly contributed to our understanding of many complex biological systems. Yet the workings of the bacterial genome, seemingly impossibly compressed within a tiny…
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Anna van 't Veer
Faculteit der Sociale Wetenschappen
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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John van Noort Lab - Chromatin Dynamics
Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.
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Helmut Schiessel Group - Theoretical Physics of Life Processes
The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.
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Plant fiber processing in the past
Basketry, cordage and textiles made of plant fibers or bark are rarely preserved in the archaeological record. By means of experimental archaeology and microwear analysis, we obtain indirect evidence about this important craft.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Tapping into Semantic Recovery
On May 31st, Bobby Ruijgrok succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bobby on this great result.
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Radio galaxies near the epoch of reionisation
This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.
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Simple rule learning is not simple: Studies on infant and adult pattern perception and production
On December 11th, Andreea Geambasu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Andreea on this great result.
- Social and Behavioural Sciences
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Lockdowns, lethality, and laissez-faire politics. Public discourses on political authorities in high-trust countries during the COVID-19 pandemic
This study looks at population response to government containment strategies during initial stages of the COVID-19 pandemic in four high-trust Northern European countries–Denmark, Germany, the Netherlands, and Sweden–with special emphasis on expressions of governmental trust.
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Unspinning chromatin: molecular mechanisms of chromatin remodeling
How do you fit two meters of DNA in a tiny compartment and at the same time are able to access the right parts of it at the right times?
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National identity predicts public health support during a global pandemic
Honorata Mazepus and Jaroslaw Kantorowicz are assistant professors at the Institute of Security and Global Affairs. Mazepus and Kantorowicz are one of the authors of this article in Nature on the role of national identity on public health support during global pandemics.
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Software and data for circular economy assessment
This thesis investigates how the assessment of circular economy (CE) at the macro-economic level can be facilitated and promoted.
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From molecules to monitoring: Integrating genetic tools into freshwater quality assessments
Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.
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Unlock the cyber crisis: Developing the prototype of an escape room-style cooperative game for cybersecurity education
The project aims to develop an escape room-style game to teach students cyber crisis management and prepare them for real-world cybersecurity challenges
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More than the Story
Considering Mesoamerican Precolonial books as material objects
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Unfolding secrets of catalysts
To construct catalysts that can produce fuels from CO2 innumerable times, we need to learn much more about how catalysis works. Irene Groot is conducting groundbreaking research into catalysis at the atomic level.
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A PCAD-model for fish to study the impact of airgun sound exposure on free-ranging cod
We are developing the conceptual framework, which is new to this taxonomic group, and evaluate the current state of the art with respect to all critical parameters and transfer functions for a fully developed Population Consequences of Acoustic Disturbance (PCAD) model.
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Project SENSYN
Making sensitive data reusable through synthetic data generation
- Archaeology
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Role of epigenetics in long-term health effects of early life stress
Can epigenetic changes explain associations between early life stress and health outcomes?
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LIFE-GREENAPI
Development & demonstration of low environmental impact innovation and optimization practices in pharma production.
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Topic: Music and health
Music can affect how we feel, think, and behave. But how do we learn about the specifics of people's responses to music so that we can apply this to health and well-being? By looking at characteristics of the music, as well as the differences between listeners, we hope to better understand as well as…
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Research
Research of the Methodology & Statstics unit of the Institute of Psychology at Leiden University.
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Standardized and reproducible measurement of decision-making in mice
In science, it is of vital importance that multiple studies corroborate the same result. Researchers therefore need to know all the details of previous experiments in order to implement the procedures as exactly as possible. However, this is becoming a major problem in neuroscience, as animal studies…
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Personal ornaments: changing identities in the Dutch Neolithic and Bronze Age
Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.
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WIC-opvarenden (Seafarers of the Dutch West India Company)
Due to the almost complete disappearance of the archive of the Old Dutch West India Company (WIC, 1621-1674) not much is known about the ships and crews of this company. In this project we start the reconstruction of this basic information making use of new digital humanities techniques to extract this…
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Archaeology and the application of Artificial Intelligence
Case-studies on use-wear analysis of prehistoric flint tools
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Land rights and access to land survey in Timor-Leste - a tool for evidence-based policy and advocacy
Develop a tool to assess land tenure, access to land and, and land tenure conflict in Timor-Leste
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Statistical literacy: ‘It’s about how we teach, not what we can teach’
Assistant Professor Lucie Zicha at Leiden University College (LUC) in The Hague is on a mission to bring statistical literacy to all undergraduate students.
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Researchers debunk earlier study: babies may not be able to learn language rules after all
For two decades, language experts were certain that babies were able to learn language rules from as young as the age of seven months. However, recent research carried out by a consortium of four Dutch baby labs led by researchers from Leiden cast doubts on this certainty. We spoke to researchers Andreea…
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Supramolecular materials: from biosensors to cell delivery devices
The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…